| Full name: zinc finger DHHC-type containing 22 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 283576 | HGNC ID: HGNC:20106 | Ensembl Gene: ENSG00000177108 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC22:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC22 | 283576 | 229805_at | 0.0526 | 0.8229 | |
| GSE26886 | ZDHHC22 | 283576 | 229805_at | 0.3161 | 0.0030 | |
| GSE45670 | ZDHHC22 | 283576 | 229805_at | 0.0898 | 0.3715 | |
| GSE53622 | ZDHHC22 | 283576 | 81032 | -0.0136 | 0.8130 | |
| GSE53624 | ZDHHC22 | 283576 | 81032 | -0.0384 | 0.6662 | |
| GSE63941 | ZDHHC22 | 283576 | 229805_at | 0.0158 | 0.9213 | |
| GSE77861 | ZDHHC22 | 283576 | 229875_at | -0.0487 | 0.7155 | |
| GSE97050 | ZDHHC22 | 283576 | A_23_P355447 | -0.1143 | 0.6404 | |
| TCGA | ZDHHC22 | 283576 | RNAseq | -1.0619 | 0.3164 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZDHHC22 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC22:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC22 | 283576 | 8 | 3 | 19 | |
| GSE20123 | ZDHHC22 | 283576 | 8 | 3 | 19 | |
| GSE43470 | ZDHHC22 | 283576 | 8 | 3 | 32 | |
| GSE46452 | ZDHHC22 | 283576 | 16 | 3 | 40 | |
| GSE47630 | ZDHHC22 | 283576 | 11 | 8 | 21 | |
| GSE54993 | ZDHHC22 | 283576 | 3 | 8 | 59 | |
| GSE54994 | ZDHHC22 | 283576 | 19 | 4 | 30 | |
| GSE60625 | ZDHHC22 | 283576 | 0 | 2 | 9 | |
| GSE74703 | ZDHHC22 | 283576 | 7 | 3 | 26 | |
| GSE74704 | ZDHHC22 | 283576 | 3 | 3 | 14 | |
| TCGA | ZDHHC22 | 283576 | 33 | 15 | 48 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of ZDHHC22:
Generating mutation plots.
Highly correlated genes for ZDHHC22:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC22 | CASC15 | 0.768409 | 3 | 0 | 3 |
| ZDHHC22 | OR2T27 | 0.715915 | 3 | 0 | 3 |
| ZDHHC22 | GPR150 | 0.697697 | 3 | 0 | 3 |
| ZDHHC22 | PVALB | 0.695997 | 3 | 0 | 3 |
| ZDHHC22 | PRDM16 | 0.689095 | 3 | 0 | 3 |
| ZDHHC22 | LYG1 | 0.672263 | 3 | 0 | 3 |
| ZDHHC22 | MYOD1 | 0.671972 | 3 | 0 | 3 |
| ZDHHC22 | OR2T1 | 0.67177 | 3 | 0 | 3 |
| ZDHHC22 | LRRIQ3 | 0.664383 | 3 | 0 | 3 |
| ZDHHC22 | NPPB | 0.658008 | 4 | 0 | 4 |
| ZDHHC22 | OR13G1 | 0.656604 | 3 | 0 | 3 |
| ZDHHC22 | SYCE1L | 0.655019 | 3 | 0 | 3 |
| ZDHHC22 | ROM1 | 0.654764 | 3 | 0 | 3 |
| ZDHHC22 | CHMP6 | 0.653481 | 4 | 0 | 3 |
| ZDHHC22 | ATXN7L2 | 0.647204 | 4 | 0 | 3 |
| ZDHHC22 | SERPINA10 | 0.645627 | 4 | 0 | 3 |
| ZDHHC22 | CHRAC1 | 0.644375 | 3 | 0 | 3 |
| ZDHHC22 | PLA2G12B | 0.641722 | 4 | 0 | 3 |
| ZDHHC22 | LINC00454 | 0.632085 | 3 | 0 | 3 |
| ZDHHC22 | SCN2A | 0.631046 | 4 | 0 | 4 |
For details and further investigation, click here
