| Full name: chordin like 2 | Alias Symbol: BNF1 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 25884 | HGNC ID: HGNC:24168 | Ensembl Gene: ENSG00000054938 | OMIM ID: 613127 |
| Drug and gene relationship at DGIdb | |||
Expression of CHRDL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHRDL2 | 25884 | 223987_at | -0.3417 | 0.7894 | |
| GSE26886 | CHRDL2 | 25884 | 223987_at | 0.4253 | 0.0072 | |
| GSE45670 | CHRDL2 | 25884 | 223987_at | -0.2260 | 0.3468 | |
| GSE53622 | CHRDL2 | 25884 | 40804 | -0.4900 | 0.0383 | |
| GSE53624 | CHRDL2 | 25884 | 40804 | -0.2978 | 0.1195 | |
| GSE63941 | CHRDL2 | 25884 | 223987_at | -2.6383 | 0.0000 | |
| GSE77861 | CHRDL2 | 25884 | 223987_at | -0.2026 | 0.0473 | |
| GSE97050 | CHRDL2 | 25884 | A_23_P13548 | 1.3491 | 0.1470 | |
| SRP064894 | CHRDL2 | 25884 | RNAseq | 1.2344 | 0.0096 | |
| SRP133303 | CHRDL2 | 25884 | RNAseq | -0.0283 | 0.9659 | |
| SRP159526 | CHRDL2 | 25884 | RNAseq | 0.8095 | 0.4223 | |
| SRP219564 | CHRDL2 | 25884 | RNAseq | 2.3577 | 0.0275 | |
| TCGA | CHRDL2 | 25884 | RNAseq | -0.3047 | 0.4212 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by CHRDL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHRDL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHRDL2 | 25884 | 7 | 8 | 15 | |
| GSE20123 | CHRDL2 | 25884 | 7 | 7 | 16 | |
| GSE43470 | CHRDL2 | 25884 | 5 | 4 | 34 | |
| GSE46452 | CHRDL2 | 25884 | 7 | 22 | 30 | |
| GSE47630 | CHRDL2 | 25884 | 6 | 14 | 20 | |
| GSE54993 | CHRDL2 | 25884 | 8 | 3 | 59 | |
| GSE54994 | CHRDL2 | 25884 | 8 | 15 | 30 | |
| GSE60625 | CHRDL2 | 25884 | 4 | 3 | 4 | |
| GSE74703 | CHRDL2 | 25884 | 4 | 3 | 29 | |
| GSE74704 | CHRDL2 | 25884 | 5 | 3 | 12 | |
| TCGA | CHRDL2 | 25884 | 23 | 32 | 41 |
Total number of gains: 84; Total number of losses: 114; Total Number of normals: 290.
Somatic mutations of CHRDL2:
Generating mutation plots.
Highly correlated genes for CHRDL2:
Showing top 20/290 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHRDL2 | SYDE1 | 0.730431 | 3 | 0 | 3 |
| CHRDL2 | P2RY8 | 0.73019 | 3 | 0 | 3 |
| CHRDL2 | CCL19 | 0.724957 | 3 | 0 | 3 |
| CHRDL2 | CCDC102B | 0.711238 | 4 | 0 | 3 |
| CHRDL2 | IGF1 | 0.706384 | 6 | 0 | 6 |
| CHRDL2 | PVRIG | 0.701601 | 3 | 0 | 3 |
| CHRDL2 | RFTN1 | 0.689598 | 3 | 0 | 3 |
| CHRDL2 | BGN | 0.688541 | 3 | 0 | 3 |
| CHRDL2 | FAM124A | 0.686602 | 3 | 0 | 3 |
| CHRDL2 | FAM8A1 | 0.683126 | 3 | 0 | 3 |
| CHRDL2 | RARRES2 | 0.682685 | 4 | 0 | 4 |
| CHRDL2 | SLC43A3 | 0.677597 | 3 | 0 | 3 |
| CHRDL2 | STAM | 0.67751 | 3 | 0 | 3 |
| CHRDL2 | PDGFRB | 0.676794 | 4 | 0 | 3 |
| CHRDL2 | FHL3 | 0.675615 | 3 | 0 | 3 |
| CHRDL2 | CLEC11A | 0.675607 | 3 | 0 | 3 |
| CHRDL2 | DZIP1L | 0.674341 | 3 | 0 | 3 |
| CHRDL2 | PPEF1 | 0.672176 | 3 | 0 | 3 |
| CHRDL2 | GPC6 | 0.671685 | 4 | 0 | 3 |
| CHRDL2 | XKR8 | 0.671348 | 3 | 0 | 3 |
For details and further investigation, click here
