| Full name: XK related 8 | Alias Symbol: FLJ10307 | ||
| Type: protein-coding gene | Cytoband: 1p35.3 | ||
| Entrez ID: 55113 | HGNC ID: HGNC:25508 | Ensembl Gene: ENSG00000158156 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of XKR8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XKR8 | 55113 | 218753_at | 0.0203 | 0.9454 | |
| GSE20347 | XKR8 | 55113 | 218753_at | -0.0640 | 0.3878 | |
| GSE23400 | XKR8 | 55113 | 218753_at | -0.0005 | 0.9914 | |
| GSE26886 | XKR8 | 55113 | 218753_at | 0.1100 | 0.3685 | |
| GSE29001 | XKR8 | 55113 | 218753_at | -0.0368 | 0.8509 | |
| GSE38129 | XKR8 | 55113 | 218753_at | -0.1082 | 0.1086 | |
| GSE45670 | XKR8 | 55113 | 218753_at | 0.0344 | 0.6897 | |
| GSE53622 | XKR8 | 55113 | 27506 | 0.0305 | 0.7113 | |
| GSE53624 | XKR8 | 55113 | 27506 | 0.0613 | 0.2673 | |
| GSE63941 | XKR8 | 55113 | 218753_at | -0.0886 | 0.6542 | |
| GSE77861 | XKR8 | 55113 | 218753_at | -0.0506 | 0.5812 | |
| GSE97050 | XKR8 | 55113 | A_23_P149496 | 0.2232 | 0.4104 | |
| SRP007169 | XKR8 | 55113 | RNAseq | -1.7713 | 0.0000 | |
| SRP008496 | XKR8 | 55113 | RNAseq | -1.7314 | 0.0000 | |
| SRP064894 | XKR8 | 55113 | RNAseq | 0.3261 | 0.1552 | |
| SRP133303 | XKR8 | 55113 | RNAseq | -0.0296 | 0.8621 | |
| SRP159526 | XKR8 | 55113 | RNAseq | 0.0462 | 0.8955 | |
| SRP193095 | XKR8 | 55113 | RNAseq | -0.1062 | 0.5160 | |
| SRP219564 | XKR8 | 55113 | RNAseq | 0.3405 | 0.4215 | |
| TCGA | XKR8 | 55113 | RNAseq | -0.3481 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by XKR8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XKR8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XKR8 | 55113 | 0 | 6 | 24 | |
| GSE20123 | XKR8 | 55113 | 0 | 5 | 25 | |
| GSE43470 | XKR8 | 55113 | 3 | 6 | 34 | |
| GSE46452 | XKR8 | 55113 | 5 | 1 | 53 | |
| GSE47630 | XKR8 | 55113 | 8 | 3 | 29 | |
| GSE54993 | XKR8 | 55113 | 2 | 1 | 67 | |
| GSE54994 | XKR8 | 55113 | 10 | 4 | 39 | |
| GSE60625 | XKR8 | 55113 | 0 | 0 | 11 | |
| GSE74703 | XKR8 | 55113 | 2 | 4 | 30 | |
| GSE74704 | XKR8 | 55113 | 0 | 0 | 20 | |
| TCGA | XKR8 | 55113 | 11 | 23 | 62 |
Total number of gains: 41; Total number of losses: 53; Total Number of normals: 394.
Somatic mutations of XKR8:
Generating mutation plots.
Highly correlated genes for XKR8:
Showing top 20/301 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XKR8 | NFATC1 | 0.778049 | 3 | 0 | 3 |
| XKR8 | ZNF792 | 0.732024 | 3 | 0 | 3 |
| XKR8 | USP5 | 0.72881 | 3 | 0 | 3 |
| XKR8 | MADD | 0.728328 | 3 | 0 | 3 |
| XKR8 | BSN | 0.724571 | 3 | 0 | 3 |
| XKR8 | SCAF4 | 0.72424 | 3 | 0 | 3 |
| XKR8 | PCBP3 | 0.715397 | 3 | 0 | 3 |
| XKR8 | ARHGAP1 | 0.710853 | 3 | 0 | 3 |
| XKR8 | STRADA | 0.710728 | 4 | 0 | 3 |
| XKR8 | ZNF747 | 0.703378 | 4 | 0 | 4 |
| XKR8 | RAC3 | 0.696837 | 3 | 0 | 3 |
| XKR8 | LHX5 | 0.692536 | 3 | 0 | 3 |
| XKR8 | MTAP | 0.691121 | 3 | 0 | 3 |
| XKR8 | TRIM26 | 0.685701 | 3 | 0 | 3 |
| XKR8 | KRTCAP2 | 0.680703 | 3 | 0 | 3 |
| XKR8 | SCARA3 | 0.68059 | 3 | 0 | 3 |
| XKR8 | SIRPG | 0.678532 | 4 | 0 | 3 |
| XKR8 | SLC5A2 | 0.67519 | 4 | 0 | 3 |
| XKR8 | IRF8 | 0.674154 | 3 | 0 | 3 |
| XKR8 | CHRDL2 | 0.671348 | 3 | 0 | 3 |
For details and further investigation, click here
