| Full name: raftlin, lipid raft linker 1 | Alias Symbol: MIG2|KIAA0084|FLJ23866|Raftlin | ||
| Type: protein-coding gene | Cytoband: 3p24.3 | ||
| Entrez ID: 23180 | HGNC ID: HGNC:30278 | Ensembl Gene: ENSG00000131378 | OMIM ID: 618210 |
| Drug and gene relationship at DGIdb | |||
Expression of RFTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFTN1 | 23180 | 212646_at | 0.1554 | 0.8394 | |
| GSE20347 | RFTN1 | 23180 | 212646_at | 0.5291 | 0.0246 | |
| GSE23400 | RFTN1 | 23180 | 212646_at | 0.2347 | 0.1598 | |
| GSE26886 | RFTN1 | 23180 | 212646_at | 1.5406 | 0.0013 | |
| GSE29001 | RFTN1 | 23180 | 212646_at | 0.9478 | 0.0063 | |
| GSE38129 | RFTN1 | 23180 | 212646_at | 0.0797 | 0.8602 | |
| GSE45670 | RFTN1 | 23180 | 212646_at | -0.5658 | 0.1820 | |
| GSE53622 | RFTN1 | 23180 | 62423 | 0.2556 | 0.0466 | |
| GSE53624 | RFTN1 | 23180 | 62423 | 0.4426 | 0.0004 | |
| GSE63941 | RFTN1 | 23180 | 212646_at | -6.1108 | 0.0000 | |
| GSE77861 | RFTN1 | 23180 | 212646_at | 0.7180 | 0.0286 | |
| GSE97050 | RFTN1 | 23180 | A_23_P315571 | -0.2456 | 0.4471 | |
| SRP007169 | RFTN1 | 23180 | RNAseq | 1.5593 | 0.0047 | |
| SRP008496 | RFTN1 | 23180 | RNAseq | 1.5192 | 0.0000 | |
| SRP064894 | RFTN1 | 23180 | RNAseq | 0.3990 | 0.0860 | |
| SRP133303 | RFTN1 | 23180 | RNAseq | 0.4297 | 0.0858 | |
| SRP159526 | RFTN1 | 23180 | RNAseq | -0.2887 | 0.4747 | |
| SRP193095 | RFTN1 | 23180 | RNAseq | 1.1509 | 0.0000 | |
| SRP219564 | RFTN1 | 23180 | RNAseq | 0.0378 | 0.9631 | |
| TCGA | RFTN1 | 23180 | RNAseq | 0.0114 | 0.9142 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by RFTN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFTN1 | 23180 | 2 | 18 | 10 | |
| GSE20123 | RFTN1 | 23180 | 2 | 18 | 10 | |
| GSE43470 | RFTN1 | 23180 | 0 | 20 | 23 | |
| GSE46452 | RFTN1 | 23180 | 2 | 17 | 40 | |
| GSE47630 | RFTN1 | 23180 | 2 | 23 | 15 | |
| GSE54993 | RFTN1 | 23180 | 6 | 1 | 63 | |
| GSE54994 | RFTN1 | 23180 | 1 | 32 | 20 | |
| GSE60625 | RFTN1 | 23180 | 5 | 0 | 6 | |
| GSE74703 | RFTN1 | 23180 | 0 | 17 | 19 | |
| GSE74704 | RFTN1 | 23180 | 1 | 12 | 7 | |
| TCGA | RFTN1 | 23180 | 1 | 68 | 27 |
Total number of gains: 22; Total number of losses: 226; Total Number of normals: 240.
Somatic mutations of RFTN1:
Generating mutation plots.
Highly correlated genes for RFTN1:
Showing top 20/1407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFTN1 | KPNA6 | 0.777499 | 3 | 0 | 3 |
| RFTN1 | C11orf96 | 0.777232 | 4 | 0 | 4 |
| RFTN1 | FBN1 | 0.775427 | 11 | 0 | 10 |
| RFTN1 | ALS2 | 0.769599 | 3 | 0 | 3 |
| RFTN1 | CLASP1 | 0.768315 | 3 | 0 | 3 |
| RFTN1 | PLBD2 | 0.763821 | 3 | 0 | 3 |
| RFTN1 | USP14 | 0.758159 | 3 | 0 | 3 |
| RFTN1 | ATL1 | 0.755334 | 3 | 0 | 3 |
| RFTN1 | EFEMP2 | 0.747726 | 12 | 0 | 11 |
| RFTN1 | FSTL1 | 0.744197 | 13 | 0 | 12 |
| RFTN1 | ZSCAN21 | 0.743238 | 3 | 0 | 3 |
| RFTN1 | LNP1 | 0.742925 | 3 | 0 | 3 |
| RFTN1 | MCAM | 0.741139 | 11 | 0 | 10 |
| RFTN1 | HNRNPU | 0.739559 | 3 | 0 | 3 |
| RFTN1 | CCM2 | 0.7395 | 3 | 0 | 3 |
| RFTN1 | WDR81 | 0.739238 | 3 | 0 | 3 |
| RFTN1 | NBPF20 | 0.73685 | 4 | 0 | 4 |
| RFTN1 | IGF2R | 0.736133 | 3 | 0 | 3 |
| RFTN1 | RASSF8 | 0.735832 | 7 | 0 | 7 |
| RFTN1 | NAV1 | 0.735429 | 3 | 0 | 3 |
For details and further investigation, click here
