| Full name: family with sequence similarity 8 member A1 | Alias Symbol: AHCP | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 51439 | HGNC ID: HGNC:16372 | Ensembl Gene: ENSG00000137414 | OMIM ID: 618409 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM8A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM8A1 | 51439 | 203420_at | -0.6233 | 0.1136 | |
| GSE20347 | FAM8A1 | 51439 | 203420_at | -0.7441 | 0.0001 | |
| GSE23400 | FAM8A1 | 51439 | 203420_at | -0.3439 | 0.0000 | |
| GSE26886 | FAM8A1 | 51439 | 203420_at | -0.3250 | 0.2193 | |
| GSE29001 | FAM8A1 | 51439 | 203420_at | -0.3809 | 0.0806 | |
| GSE38129 | FAM8A1 | 51439 | 203420_at | -0.8229 | 0.0000 | |
| GSE45670 | FAM8A1 | 51439 | 203420_at | -0.8994 | 0.0000 | |
| GSE63941 | FAM8A1 | 51439 | 203420_at | -1.8338 | 0.0026 | |
| GSE77861 | FAM8A1 | 51439 | 203420_at | -0.4983 | 0.1907 | |
| GSE97050 | FAM8A1 | 51439 | A_23_P133648 | -0.4849 | 0.1118 | |
| SRP007169 | FAM8A1 | 51439 | RNAseq | -0.9556 | 0.0117 | |
| SRP008496 | FAM8A1 | 51439 | RNAseq | -0.6926 | 0.0009 | |
| SRP064894 | FAM8A1 | 51439 | RNAseq | -0.4357 | 0.0433 | |
| SRP133303 | FAM8A1 | 51439 | RNAseq | -0.3950 | 0.0241 | |
| SRP159526 | FAM8A1 | 51439 | RNAseq | -0.1028 | 0.7210 | |
| SRP193095 | FAM8A1 | 51439 | RNAseq | -0.5643 | 0.0000 | |
| SRP219564 | FAM8A1 | 51439 | RNAseq | -0.3967 | 0.2029 | |
| TCGA | FAM8A1 | 51439 | RNAseq | -0.2481 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FAM8A1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FAM8A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM8A1 | 51439 | 2 | 5 | 23 | |
| GSE20123 | FAM8A1 | 51439 | 2 | 5 | 23 | |
| GSE43470 | FAM8A1 | 51439 | 9 | 0 | 34 | |
| GSE46452 | FAM8A1 | 51439 | 1 | 10 | 48 | |
| GSE47630 | FAM8A1 | 51439 | 7 | 7 | 26 | |
| GSE54993 | FAM8A1 | 51439 | 1 | 1 | 68 | |
| GSE54994 | FAM8A1 | 51439 | 10 | 3 | 40 | |
| GSE60625 | FAM8A1 | 51439 | 0 | 1 | 10 | |
| GSE74703 | FAM8A1 | 51439 | 8 | 0 | 28 | |
| GSE74704 | FAM8A1 | 51439 | 2 | 2 | 16 | |
| TCGA | FAM8A1 | 51439 | 16 | 26 | 54 |
Total number of gains: 58; Total number of losses: 60; Total Number of normals: 370.
Somatic mutations of FAM8A1:
Generating mutation plots.
Highly correlated genes for FAM8A1:
Showing top 20/1232 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM8A1 | BVES | 0.817304 | 3 | 0 | 3 |
| FAM8A1 | XKR4 | 0.795285 | 3 | 0 | 3 |
| FAM8A1 | LRRN4CL | 0.781488 | 4 | 0 | 4 |
| FAM8A1 | LRRK2 | 0.781104 | 5 | 0 | 5 |
| FAM8A1 | CNRIP1 | 0.779797 | 4 | 0 | 4 |
| FAM8A1 | FIBIN | 0.767074 | 5 | 0 | 5 |
| FAM8A1 | GPIHBP1 | 0.766263 | 3 | 0 | 3 |
| FAM8A1 | MAP4K3 | 0.765852 | 3 | 0 | 3 |
| FAM8A1 | TMEM170B | 0.76441 | 4 | 0 | 4 |
| FAM8A1 | RAB9B | 0.762614 | 4 | 0 | 4 |
| FAM8A1 | STARD9 | 0.761428 | 4 | 0 | 4 |
| FAM8A1 | TSPAN31 | 0.757529 | 3 | 0 | 3 |
| FAM8A1 | ZNF354C | 0.753176 | 3 | 0 | 3 |
| FAM8A1 | ARHGAP31 | 0.751925 | 4 | 0 | 4 |
| FAM8A1 | DACT3 | 0.749256 | 3 | 0 | 3 |
| FAM8A1 | JAM3 | 0.745983 | 6 | 0 | 6 |
| FAM8A1 | UBXN1 | 0.744019 | 3 | 0 | 3 |
| FAM8A1 | FOXF1 | 0.743948 | 6 | 0 | 6 |
| FAM8A1 | PPWD1 | 0.741286 | 3 | 0 | 3 |
| FAM8A1 | C7 | 0.740772 | 6 | 0 | 6 |
For details and further investigation, click here
