| Full name: C-type lectin domain containing 11A | Alias Symbol: P47|LSLCL|CLECSF3 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 6320 | HGNC ID: HGNC:10576 | Ensembl Gene: ENSG00000105472 | OMIM ID: 604713 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC11A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC11A | 6320 | 211709_s_at | 0.3441 | 0.6205 | |
| GSE20347 | CLEC11A | 6320 | 210783_x_at | 0.1466 | 0.1221 | |
| GSE23400 | CLEC11A | 6320 | 211709_s_at | 0.2165 | 0.0004 | |
| GSE26886 | CLEC11A | 6320 | 211709_s_at | 1.5220 | 0.0000 | |
| GSE29001 | CLEC11A | 6320 | 211709_s_at | 0.4221 | 0.1953 | |
| GSE38129 | CLEC11A | 6320 | 211709_s_at | 0.6576 | 0.0013 | |
| GSE45670 | CLEC11A | 6320 | 211709_s_at | -0.2036 | 0.4378 | |
| GSE53622 | CLEC11A | 6320 | 39171 | 0.7414 | 0.0000 | |
| GSE53624 | CLEC11A | 6320 | 39171 | 1.1349 | 0.0000 | |
| GSE63941 | CLEC11A | 6320 | 211709_s_at | -3.7839 | 0.0002 | |
| GSE77861 | CLEC11A | 6320 | 211709_s_at | 0.0468 | 0.8771 | |
| GSE97050 | CLEC11A | 6320 | A_33_P3229032 | 0.4434 | 0.1406 | |
| SRP007169 | CLEC11A | 6320 | RNAseq | 2.1261 | 0.0008 | |
| SRP008496 | CLEC11A | 6320 | RNAseq | 3.4074 | 0.0000 | |
| SRP064894 | CLEC11A | 6320 | RNAseq | 1.9680 | 0.0000 | |
| SRP133303 | CLEC11A | 6320 | RNAseq | 1.2425 | 0.0008 | |
| SRP159526 | CLEC11A | 6320 | RNAseq | 0.8061 | 0.0108 | |
| SRP219564 | CLEC11A | 6320 | RNAseq | 1.6857 | 0.0084 | |
| TCGA | CLEC11A | 6320 | RNAseq | 0.4021 | 0.0004 |
Upregulated datasets: 7; Downregulated datasets: 1.
Survival by CLEC11A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC11A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC11A | 6320 | 3 | 4 | 23 | |
| GSE20123 | CLEC11A | 6320 | 3 | 3 | 24 | |
| GSE43470 | CLEC11A | 6320 | 4 | 11 | 28 | |
| GSE46452 | CLEC11A | 6320 | 45 | 1 | 13 | |
| GSE47630 | CLEC11A | 6320 | 9 | 6 | 25 | |
| GSE54993 | CLEC11A | 6320 | 17 | 4 | 49 | |
| GSE54994 | CLEC11A | 6320 | 4 | 14 | 35 | |
| GSE60625 | CLEC11A | 6320 | 9 | 0 | 2 | |
| GSE74703 | CLEC11A | 6320 | 4 | 7 | 25 | |
| GSE74704 | CLEC11A | 6320 | 3 | 1 | 16 | |
| TCGA | CLEC11A | 6320 | 14 | 19 | 63 |
Total number of gains: 115; Total number of losses: 70; Total Number of normals: 303.
Somatic mutations of CLEC11A:
Generating mutation plots.
Highly correlated genes for CLEC11A:
Showing top 20/1070 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC11A | MIER2 | 0.77887 | 3 | 0 | 3 |
| CLEC11A | MICAL1 | 0.775689 | 4 | 0 | 4 |
| CLEC11A | RGS1 | 0.77 | 3 | 0 | 3 |
| CLEC11A | POLR2A | 0.756356 | 3 | 0 | 3 |
| CLEC11A | KISS1R | 0.743745 | 3 | 0 | 3 |
| CLEC11A | APBB1IP | 0.737494 | 3 | 0 | 3 |
| CLEC11A | ANGPTL4 | 0.735094 | 3 | 0 | 3 |
| CLEC11A | A1BG | 0.733296 | 6 | 0 | 5 |
| CLEC11A | C11orf96 | 0.728895 | 4 | 0 | 4 |
| CLEC11A | NUP43 | 0.722769 | 3 | 0 | 3 |
| CLEC11A | B3GALT6 | 0.722153 | 4 | 0 | 4 |
| CLEC11A | MAPK8IP3 | 0.722061 | 3 | 0 | 3 |
| CLEC11A | DAPK3 | 0.715814 | 4 | 0 | 4 |
| CLEC11A | PSMG3 | 0.714406 | 3 | 0 | 3 |
| CLEC11A | TMEM132A | 0.714371 | 5 | 0 | 4 |
| CLEC11A | SPON2 | 0.709417 | 4 | 0 | 4 |
| CLEC11A | TRIM47 | 0.709063 | 3 | 0 | 3 |
| CLEC11A | PTX3 | 0.707576 | 3 | 0 | 3 |
| CLEC11A | SLC43A2 | 0.702881 | 6 | 0 | 5 |
| CLEC11A | TP53I13 | 0.702386 | 5 | 0 | 5 |
For details and further investigation, click here
