| Full name: retinoic acid receptor responder 2 | Alias Symbol: TIG2|HP10433 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 5919 | HGNC ID: HGNC:9868 | Ensembl Gene: ENSG00000106538 | OMIM ID: 601973 |
| Drug and gene relationship at DGIdb | |||
Expression of RARRES2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RARRES2 | 5919 | 209496_at | -0.1535 | 0.9307 | |
| GSE20347 | RARRES2 | 5919 | 209496_at | 0.8500 | 0.0031 | |
| GSE23400 | RARRES2 | 5919 | 209496_at | 0.2908 | 0.0724 | |
| GSE26886 | RARRES2 | 5919 | 209496_at | 1.5850 | 0.0020 | |
| GSE29001 | RARRES2 | 5919 | 209496_at | 0.2141 | 0.6380 | |
| GSE38129 | RARRES2 | 5919 | 209496_at | 0.3582 | 0.5038 | |
| GSE45670 | RARRES2 | 5919 | 209496_at | -1.4298 | 0.0017 | |
| GSE53622 | RARRES2 | 5919 | 112642 | 0.5194 | 0.0030 | |
| GSE53624 | RARRES2 | 5919 | 112642 | 0.5393 | 0.0006 | |
| GSE63941 | RARRES2 | 5919 | 209496_at | -6.0581 | 0.0000 | |
| GSE77861 | RARRES2 | 5919 | 209496_at | 0.3232 | 0.2210 | |
| GSE97050 | RARRES2 | 5919 | A_23_P134237 | -0.0146 | 0.9725 | |
| SRP007169 | RARRES2 | 5919 | RNAseq | 3.5429 | 0.0000 | |
| SRP008496 | RARRES2 | 5919 | RNAseq | 5.0164 | 0.0000 | |
| SRP064894 | RARRES2 | 5919 | RNAseq | 0.5073 | 0.2193 | |
| SRP133303 | RARRES2 | 5919 | RNAseq | 1.1071 | 0.0011 | |
| SRP159526 | RARRES2 | 5919 | RNAseq | 0.5457 | 0.0323 | |
| SRP193095 | RARRES2 | 5919 | RNAseq | 1.7263 | 0.0001 | |
| SRP219564 | RARRES2 | 5919 | RNAseq | 0.1380 | 0.8734 | |
| TCGA | RARRES2 | 5919 | RNAseq | -0.2232 | 0.1109 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by RARRES2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RARRES2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RARRES2 | 5919 | 2 | 4 | 24 | |
| GSE20123 | RARRES2 | 5919 | 2 | 4 | 24 | |
| GSE43470 | RARRES2 | 5919 | 2 | 5 | 36 | |
| GSE46452 | RARRES2 | 5919 | 7 | 2 | 50 | |
| GSE47630 | RARRES2 | 5919 | 6 | 8 | 26 | |
| GSE54993 | RARRES2 | 5919 | 3 | 3 | 64 | |
| GSE54994 | RARRES2 | 5919 | 6 | 8 | 39 | |
| GSE60625 | RARRES2 | 5919 | 0 | 0 | 11 | |
| GSE74703 | RARRES2 | 5919 | 2 | 4 | 30 | |
| GSE74704 | RARRES2 | 5919 | 1 | 4 | 15 | |
| TCGA | RARRES2 | 5919 | 25 | 27 | 44 |
Total number of gains: 56; Total number of losses: 69; Total Number of normals: 363.
Somatic mutations of RARRES2:
Generating mutation plots.
Highly correlated genes for RARRES2:
Showing top 20/857 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RARRES2 | ISLR | 0.773081 | 13 | 0 | 13 |
| RARRES2 | CTSK | 0.771924 | 12 | 0 | 12 |
| RARRES2 | FBN1 | 0.77072 | 10 | 0 | 9 |
| RARRES2 | CNRIP1 | 0.766111 | 8 | 0 | 8 |
| RARRES2 | EMILIN1 | 0.759424 | 13 | 0 | 13 |
| RARRES2 | LAMA4 | 0.754501 | 11 | 0 | 11 |
| RARRES2 | EFEMP2 | 0.753011 | 12 | 0 | 12 |
| RARRES2 | C11orf96 | 0.752836 | 4 | 0 | 4 |
| RARRES2 | DNM3OS | 0.752646 | 4 | 0 | 3 |
| RARRES2 | OLFML1 | 0.7495 | 11 | 0 | 11 |
| RARRES2 | PCOLCE | 0.744288 | 12 | 0 | 12 |
| RARRES2 | TMEM119 | 0.743007 | 8 | 0 | 8 |
| RARRES2 | DCN | 0.742378 | 12 | 0 | 12 |
| RARRES2 | COL6A2 | 0.73808 | 12 | 0 | 12 |
| RARRES2 | MMP2 | 0.737431 | 10 | 0 | 9 |
| RARRES2 | AEBP1 | 0.731974 | 13 | 0 | 12 |
| RARRES2 | GREM1 | 0.731171 | 13 | 0 | 13 |
| RARRES2 | SGCD | 0.730446 | 8 | 0 | 8 |
| RARRES2 | FILIP1L | 0.729411 | 12 | 0 | 12 |
| RARRES2 | OLFML3 | 0.729332 | 13 | 0 | 12 |
For details and further investigation, click here
