| Full name: CDGSH iron sulfur domain 1 | Alias Symbol: MDS029|mitoNEET | ||
| Type: protein-coding gene | Cytoband: 10q21.1 | ||
| Entrez ID: 55847 | HGNC ID: HGNC:30880 | Ensembl Gene: ENSG00000122873 | OMIM ID: 611932 |
| Drug and gene relationship at DGIdb | |||
Expression of CISD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CISD1 | 55847 | 218597_s_at | -0.1454 | 0.6734 | |
| GSE20347 | CISD1 | 55847 | 218597_s_at | -0.3035 | 0.1988 | |
| GSE23400 | CISD1 | 55847 | 218597_s_at | 0.0752 | 0.4973 | |
| GSE26886 | CISD1 | 55847 | 218597_s_at | 0.3075 | 0.0441 | |
| GSE29001 | CISD1 | 55847 | 218597_s_at | -0.1454 | 0.6431 | |
| GSE38129 | CISD1 | 55847 | 218597_s_at | -0.1610 | 0.5483 | |
| GSE45670 | CISD1 | 55847 | 218597_s_at | -0.0384 | 0.8342 | |
| GSE53622 | CISD1 | 55847 | 154025 | -0.2864 | 0.0001 | |
| GSE53624 | CISD1 | 55847 | 154025 | 0.1492 | 0.0284 | |
| GSE63941 | CISD1 | 55847 | 218597_s_at | -0.6572 | 0.2633 | |
| GSE77861 | CISD1 | 55847 | 218597_s_at | -0.3229 | 0.3345 | |
| GSE97050 | CISD1 | 55847 | A_23_P35467 | -0.1869 | 0.5499 | |
| SRP007169 | CISD1 | 55847 | RNAseq | -0.3174 | 0.5249 | |
| SRP008496 | CISD1 | 55847 | RNAseq | 0.1640 | 0.6033 | |
| SRP064894 | CISD1 | 55847 | RNAseq | 0.1251 | 0.5817 | |
| SRP133303 | CISD1 | 55847 | RNAseq | 0.2314 | 0.1678 | |
| SRP159526 | CISD1 | 55847 | RNAseq | -0.4449 | 0.2717 | |
| SRP193095 | CISD1 | 55847 | RNAseq | -0.4997 | 0.0023 | |
| SRP219564 | CISD1 | 55847 | RNAseq | -0.2991 | 0.5615 | |
| TCGA | CISD1 | 55847 | RNAseq | -0.0350 | 0.5605 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CISD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CISD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CISD1 | 55847 | 2 | 6 | 22 | |
| GSE20123 | CISD1 | 55847 | 2 | 6 | 22 | |
| GSE43470 | CISD1 | 55847 | 2 | 5 | 36 | |
| GSE46452 | CISD1 | 55847 | 0 | 12 | 47 | |
| GSE47630 | CISD1 | 55847 | 4 | 12 | 24 | |
| GSE54993 | CISD1 | 55847 | 9 | 0 | 61 | |
| GSE54994 | CISD1 | 55847 | 3 | 10 | 40 | |
| GSE60625 | CISD1 | 55847 | 0 | 0 | 11 | |
| GSE74703 | CISD1 | 55847 | 2 | 3 | 31 | |
| GSE74704 | CISD1 | 55847 | 1 | 4 | 15 | |
| TCGA | CISD1 | 55847 | 10 | 23 | 63 |
Total number of gains: 35; Total number of losses: 81; Total Number of normals: 372.
Somatic mutations of CISD1:
Generating mutation plots.
Highly correlated genes for CISD1:
Showing top 20/314 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CISD1 | EBF3 | 0.808506 | 3 | 0 | 3 |
| CISD1 | LDOC1 | 0.754141 | 3 | 0 | 3 |
| CISD1 | SDHAF2 | 0.726313 | 3 | 0 | 3 |
| CISD1 | RPA2 | 0.720765 | 3 | 0 | 3 |
| CISD1 | STAMBPL1 | 0.718121 | 3 | 0 | 3 |
| CISD1 | ASB8 | 0.717841 | 4 | 0 | 3 |
| CISD1 | SPG7 | 0.712887 | 3 | 0 | 3 |
| CISD1 | NDUFA12 | 0.708145 | 3 | 0 | 3 |
| CISD1 | RNF14 | 0.707988 | 4 | 0 | 4 |
| CISD1 | CLP1 | 0.705866 | 3 | 0 | 3 |
| CISD1 | AIFM1 | 0.701358 | 3 | 0 | 3 |
| CISD1 | GSPT1 | 0.698648 | 4 | 0 | 4 |
| CISD1 | TCTN1 | 0.698049 | 3 | 0 | 3 |
| CISD1 | OAZ2 | 0.697412 | 3 | 0 | 3 |
| CISD1 | CDC26 | 0.687713 | 4 | 0 | 3 |
| CISD1 | PRELP | 0.684455 | 3 | 0 | 3 |
| CISD1 | WWC3 | 0.681759 | 5 | 0 | 3 |
| CISD1 | UBE2M | 0.679549 | 5 | 0 | 5 |
| CISD1 | ARL16 | 0.679519 | 4 | 0 | 4 |
| CISD1 | MAPKAPK5 | 0.67688 | 3 | 0 | 3 |
For details and further investigation, click here
