| Full name: tectonic family member 1 | Alias Symbol: FLJ21127|TECT1|JBTS13 | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 79600 | HGNC ID: HGNC:26113 | Ensembl Gene: ENSG00000204852 | OMIM ID: 609863 |
| Drug and gene relationship at DGIdb | |||
Expression of TCTN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TCTN1 | 79600 | 218584_at | 0.0057 | 0.9916 | |
| GSE20347 | TCTN1 | 79600 | 218584_at | 0.1200 | 0.4800 | |
| GSE23400 | TCTN1 | 79600 | 218584_at | -0.0208 | 0.6567 | |
| GSE26886 | TCTN1 | 79600 | 218584_at | 0.6074 | 0.0036 | |
| GSE29001 | TCTN1 | 79600 | 218584_at | -0.1224 | 0.5862 | |
| GSE38129 | TCTN1 | 79600 | 218584_at | 0.1828 | 0.2290 | |
| GSE45670 | TCTN1 | 79600 | 218584_at | -0.0715 | 0.7128 | |
| GSE53622 | TCTN1 | 79600 | 58128 | 0.4192 | 0.0000 | |
| GSE53624 | TCTN1 | 79600 | 90479 | 0.4549 | 0.0000 | |
| GSE63941 | TCTN1 | 79600 | 218584_at | -0.7653 | 0.0609 | |
| GSE77861 | TCTN1 | 79600 | 1556864_at | -0.1010 | 0.4510 | |
| GSE97050 | TCTN1 | 79600 | A_33_P3210965 | 0.0561 | 0.8887 | |
| SRP007169 | TCTN1 | 79600 | RNAseq | -0.4999 | 0.3892 | |
| SRP008496 | TCTN1 | 79600 | RNAseq | 0.4858 | 0.2212 | |
| SRP064894 | TCTN1 | 79600 | RNAseq | 0.1563 | 0.4276 | |
| SRP133303 | TCTN1 | 79600 | RNAseq | 0.2802 | 0.0365 | |
| SRP159526 | TCTN1 | 79600 | RNAseq | 1.1043 | 0.0015 | |
| SRP193095 | TCTN1 | 79600 | RNAseq | 0.3426 | 0.0009 | |
| SRP219564 | TCTN1 | 79600 | RNAseq | 0.1721 | 0.6296 | |
| TCGA | TCTN1 | 79600 | RNAseq | 0.1278 | 0.1708 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TCTN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TCTN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TCTN1 | 79600 | 5 | 3 | 22 | |
| GSE20123 | TCTN1 | 79600 | 5 | 3 | 22 | |
| GSE43470 | TCTN1 | 79600 | 2 | 1 | 40 | |
| GSE46452 | TCTN1 | 79600 | 9 | 1 | 49 | |
| GSE47630 | TCTN1 | 79600 | 9 | 3 | 28 | |
| GSE54993 | TCTN1 | 79600 | 0 | 5 | 65 | |
| GSE54994 | TCTN1 | 79600 | 5 | 2 | 46 | |
| GSE60625 | TCTN1 | 79600 | 0 | 0 | 11 | |
| GSE74703 | TCTN1 | 79600 | 2 | 0 | 34 | |
| GSE74704 | TCTN1 | 79600 | 2 | 2 | 16 | |
| TCGA | TCTN1 | 79600 | 22 | 11 | 63 |
Total number of gains: 61; Total number of losses: 31; Total Number of normals: 396.
Somatic mutations of TCTN1:
Generating mutation plots.
Highly correlated genes for TCTN1:
Showing top 20/672 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TCTN1 | TNFRSF9 | 0.791594 | 3 | 0 | 3 |
| TCTN1 | RPS19BP1 | 0.787149 | 3 | 0 | 3 |
| TCTN1 | ZNF496 | 0.786233 | 3 | 0 | 3 |
| TCTN1 | ENO2 | 0.783056 | 3 | 0 | 3 |
| TCTN1 | ARHGAP42 | 0.773874 | 3 | 0 | 3 |
| TCTN1 | SPI1 | 0.764339 | 3 | 0 | 3 |
| TCTN1 | SSNA1 | 0.762852 | 3 | 0 | 3 |
| TCTN1 | ADH5 | 0.755023 | 3 | 0 | 3 |
| TCTN1 | ELMOD3 | 0.746143 | 3 | 0 | 3 |
| TCTN1 | PILRA | 0.74402 | 3 | 0 | 3 |
| TCTN1 | LIPT1 | 0.73891 | 3 | 0 | 3 |
| TCTN1 | TMEM219 | 0.736883 | 3 | 0 | 3 |
| TCTN1 | ZCCHC3 | 0.727483 | 3 | 0 | 3 |
| TCTN1 | TCL1B | 0.725862 | 3 | 0 | 3 |
| TCTN1 | CXCR5 | 0.72435 | 3 | 0 | 3 |
| TCTN1 | TEAD2 | 0.717608 | 4 | 0 | 4 |
| TCTN1 | RAB34 | 0.716329 | 3 | 0 | 3 |
| TCTN1 | ASB7 | 0.715872 | 3 | 0 | 3 |
| TCTN1 | JTB | 0.714056 | 3 | 0 | 3 |
| TCTN1 | STAT5A | 0.710916 | 4 | 0 | 3 |
For details and further investigation, click here
