| Full name: proline and arginine rich end leucine rich repeat protein | Alias Symbol: SLRR2A|prolargin | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 5549 | HGNC ID: HGNC:9357 | Ensembl Gene: ENSG00000188783 | OMIM ID: 601914 |
| Drug and gene relationship at DGIdb | |||
Expression of PRELP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRELP | 5549 | 228224_at | -1.9070 | 0.0805 | |
| GSE20347 | PRELP | 5549 | 37022_at | 0.0077 | 0.9527 | |
| GSE23400 | PRELP | 5549 | 37022_at | -0.2103 | 0.0000 | |
| GSE26886 | PRELP | 5549 | 37022_at | 0.0494 | 0.7396 | |
| GSE29001 | PRELP | 5549 | 37022_at | -0.1604 | 0.2230 | |
| GSE38129 | PRELP | 5549 | 204223_at | -0.9473 | 0.0079 | |
| GSE45670 | PRELP | 5549 | 37022_at | -0.4409 | 0.0000 | |
| GSE53622 | PRELP | 5549 | 53359 | -1.5891 | 0.0000 | |
| GSE53624 | PRELP | 5549 | 53359 | -1.8732 | 0.0000 | |
| GSE63941 | PRELP | 5549 | 37022_at | -0.1391 | 0.4015 | |
| GSE77861 | PRELP | 5549 | 37022_at | -0.0533 | 0.6063 | |
| GSE97050 | PRELP | 5549 | A_33_P3234882 | -1.5988 | 0.0454 | |
| SRP007169 | PRELP | 5549 | RNAseq | 2.7931 | 0.0004 | |
| SRP064894 | PRELP | 5549 | RNAseq | -0.8696 | 0.0717 | |
| SRP133303 | PRELP | 5549 | RNAseq | -1.1379 | 0.0077 | |
| SRP159526 | PRELP | 5549 | RNAseq | -1.9318 | 0.0000 | |
| SRP193095 | PRELP | 5549 | RNAseq | 0.3095 | 0.0965 | |
| SRP219564 | PRELP | 5549 | RNAseq | -1.5235 | 0.1426 | |
| TCGA | PRELP | 5549 | RNAseq | -0.8541 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 5.
Survival by PRELP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRELP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRELP | 5549 | 11 | 0 | 19 | |
| GSE20123 | PRELP | 5549 | 11 | 0 | 19 | |
| GSE43470 | PRELP | 5549 | 6 | 0 | 37 | |
| GSE46452 | PRELP | 5549 | 3 | 1 | 55 | |
| GSE47630 | PRELP | 5549 | 14 | 0 | 26 | |
| GSE54993 | PRELP | 5549 | 0 | 6 | 64 | |
| GSE54994 | PRELP | 5549 | 15 | 0 | 38 | |
| GSE60625 | PRELP | 5549 | 0 | 0 | 11 | |
| GSE74703 | PRELP | 5549 | 6 | 0 | 30 | |
| GSE74704 | PRELP | 5549 | 5 | 0 | 15 | |
| TCGA | PRELP | 5549 | 44 | 4 | 48 |
Total number of gains: 115; Total number of losses: 11; Total Number of normals: 362.
Somatic mutations of PRELP:
Generating mutation plots.
Highly correlated genes for PRELP:
Showing top 20/1413 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRELP | MAMDC2 | 0.833536 | 5 | 0 | 5 |
| PRELP | MSRB3 | 0.798514 | 5 | 0 | 5 |
| PRELP | FBXL3 | 0.791274 | 3 | 0 | 3 |
| PRELP | CLEC3B | 0.790771 | 3 | 0 | 3 |
| PRELP | CYP21A2 | 0.782362 | 3 | 0 | 3 |
| PRELP | RBPMS2 | 0.776412 | 6 | 0 | 6 |
| PRELP | TNFSF12 | 0.776409 | 3 | 0 | 3 |
| PRELP | RNASE4 | 0.774395 | 5 | 0 | 5 |
| PRELP | TMOD1 | 0.774066 | 6 | 0 | 6 |
| PRELP | GPRASP1 | 0.769956 | 7 | 0 | 6 |
| PRELP | TGFBR3 | 0.762534 | 7 | 0 | 7 |
| PRELP | NR2F1 | 0.762185 | 3 | 0 | 3 |
| PRELP | TCEAL6 | 0.760847 | 3 | 0 | 3 |
| PRELP | WWTR1 | 0.757535 | 5 | 0 | 5 |
| PRELP | OGN | 0.757016 | 8 | 0 | 7 |
| PRELP | DNAJC27 | 0.754195 | 3 | 0 | 3 |
| PRELP | BBS1 | 0.752138 | 4 | 0 | 3 |
| PRELP | KCNK2 | 0.748939 | 3 | 0 | 3 |
| PRELP | PRKAR2B | 0.747312 | 8 | 0 | 8 |
| PRELP | TSPAN2 | 0.74655 | 7 | 0 | 7 |
For details and further investigation, click here
