| Full name: EBF transcription factor 3 | Alias Symbol: COE3|DKFZp667B0210 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 253738 | HGNC ID: HGNC:19087 | Ensembl Gene: ENSG00000108001 | OMIM ID: 607407 |
| Drug and gene relationship at DGIdb | |||
Expression of EBF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EBF3 | 253738 | 227243_s_at | -0.8144 | 0.1522 | |
| GSE26886 | EBF3 | 253738 | 227243_s_at | 0.2047 | 0.1593 | |
| GSE45670 | EBF3 | 253738 | 227243_s_at | -0.9184 | 0.0015 | |
| GSE53622 | EBF3 | 253738 | 12310 | -0.9231 | 0.0000 | |
| GSE53624 | EBF3 | 253738 | 12310 | -0.7448 | 0.0000 | |
| GSE63941 | EBF3 | 253738 | 1559796_at | -0.1190 | 0.5390 | |
| GSE77861 | EBF3 | 253738 | 227243_s_at | -0.0904 | 0.3401 | |
| GSE97050 | EBF3 | 253738 | A_33_P3386067 | -0.0654 | 0.8261 | |
| SRP133303 | EBF3 | 253738 | RNAseq | -0.9101 | 0.0061 | |
| SRP159526 | EBF3 | 253738 | RNAseq | -0.1559 | 0.7726 | |
| SRP219564 | EBF3 | 253738 | RNAseq | 0.2672 | 0.5997 | |
| TCGA | EBF3 | 253738 | RNAseq | -0.5668 | 0.0396 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EBF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EBF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EBF3 | 253738 | 2 | 8 | 20 | |
| GSE20123 | EBF3 | 253738 | 2 | 8 | 20 | |
| GSE43470 | EBF3 | 253738 | 0 | 10 | 33 | |
| GSE46452 | EBF3 | 253738 | 0 | 11 | 48 | |
| GSE47630 | EBF3 | 253738 | 4 | 13 | 23 | |
| GSE54993 | EBF3 | 253738 | 8 | 1 | 61 | |
| GSE54994 | EBF3 | 253738 | 1 | 9 | 43 | |
| GSE60625 | EBF3 | 253738 | 0 | 0 | 11 | |
| GSE74703 | EBF3 | 253738 | 0 | 6 | 30 | |
| GSE74704 | EBF3 | 253738 | 2 | 3 | 15 | |
| TCGA | EBF3 | 253738 | 7 | 28 | 61 |
Total number of gains: 26; Total number of losses: 97; Total Number of normals: 365.
Somatic mutations of EBF3:
Generating mutation plots.
Highly correlated genes for EBF3:
Showing top 20/664 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EBF3 | FAM13C | 0.862519 | 3 | 0 | 3 |
| EBF3 | SLIT3 | 0.854727 | 3 | 0 | 3 |
| EBF3 | PEG3 | 0.854589 | 3 | 0 | 3 |
| EBF3 | CYP4V2 | 0.823822 | 3 | 0 | 3 |
| EBF3 | CISD1 | 0.808506 | 3 | 0 | 3 |
| EBF3 | RNASE4 | 0.79292 | 3 | 0 | 3 |
| EBF3 | GNG11 | 0.7841 | 6 | 0 | 6 |
| EBF3 | MYCT1 | 0.783672 | 5 | 0 | 5 |
| EBF3 | CYYR1 | 0.77817 | 5 | 0 | 5 |
| EBF3 | ECSCR | 0.775565 | 5 | 0 | 5 |
| EBF3 | ID4 | 0.769392 | 3 | 0 | 3 |
| EBF3 | FIBIN | 0.761743 | 4 | 0 | 4 |
| EBF3 | JAM2 | 0.759738 | 5 | 0 | 5 |
| EBF3 | PDE1A | 0.755825 | 5 | 0 | 5 |
| EBF3 | FRY | 0.75354 | 4 | 0 | 4 |
| EBF3 | NPY1R | 0.751437 | 5 | 0 | 5 |
| EBF3 | ADAMTS5 | 0.747788 | 5 | 0 | 5 |
| EBF3 | DCHS1 | 0.732117 | 5 | 0 | 5 |
| EBF3 | LYVE1 | 0.73183 | 5 | 0 | 5 |
| EBF3 | HNRNPH3 | 0.731461 | 3 | 0 | 3 |
For details and further investigation, click here
