| Full name: apoptosis inducing factor mitochondria associated 1 | Alias Symbol: AIF|CMTX4|DFNX5 | ||
| Type: protein-coding gene | Cytoband: Xq26.1 | ||
| Entrez ID: 9131 | HGNC ID: HGNC:8768 | Ensembl Gene: ENSG00000156709 | OMIM ID: 300169 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AIFM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AIFM1 | 9131 | 205512_s_at | 0.0978 | 0.8124 | |
| GSE20347 | AIFM1 | 9131 | 205512_s_at | 0.3483 | 0.0257 | |
| GSE23400 | AIFM1 | 9131 | 205512_s_at | 0.3946 | 0.0000 | |
| GSE26886 | AIFM1 | 9131 | 205512_s_at | -0.9055 | 0.0048 | |
| GSE29001 | AIFM1 | 9131 | 205512_s_at | 0.4305 | 0.3557 | |
| GSE38129 | AIFM1 | 9131 | 205512_s_at | 0.3850 | 0.0100 | |
| GSE45670 | AIFM1 | 9131 | 205512_s_at | 0.4734 | 0.0109 | |
| GSE53622 | AIFM1 | 9131 | 78114 | 0.0474 | 0.6219 | |
| GSE53624 | AIFM1 | 9131 | 78114 | 0.3894 | 0.0000 | |
| GSE63941 | AIFM1 | 9131 | 205512_s_at | 0.3942 | 0.4125 | |
| GSE77861 | AIFM1 | 9131 | 205512_s_at | 0.2749 | 0.1251 | |
| GSE97050 | AIFM1 | 9131 | A_23_P72537 | 0.0682 | 0.7804 | |
| SRP007169 | AIFM1 | 9131 | RNAseq | 2.1689 | 0.0014 | |
| SRP064894 | AIFM1 | 9131 | RNAseq | 0.5591 | 0.0000 | |
| SRP133303 | AIFM1 | 9131 | RNAseq | 0.5066 | 0.0115 | |
| SRP159526 | AIFM1 | 9131 | RNAseq | 0.4287 | 0.1084 | |
| SRP193095 | AIFM1 | 9131 | RNAseq | -0.1033 | 0.4347 | |
| SRP219564 | AIFM1 | 9131 | RNAseq | 0.3372 | 0.4700 | |
| TCGA | AIFM1 | 9131 | RNAseq | -0.1924 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by AIFM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AIFM1:
No record found for this gene.
Somatic mutations of AIFM1:
Generating mutation plots.
Highly correlated genes for AIFM1:
Showing top 20/871 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AIFM1 | AEBP2 | 0.821814 | 3 | 0 | 3 |
| AIFM1 | ALG10 | 0.800759 | 3 | 0 | 3 |
| AIFM1 | C12orf57 | 0.785841 | 3 | 0 | 3 |
| AIFM1 | EIF4ENIF1 | 0.780051 | 3 | 0 | 3 |
| AIFM1 | SNX17 | 0.764732 | 4 | 0 | 4 |
| AIFM1 | OAT | 0.75344 | 3 | 0 | 3 |
| AIFM1 | IMPDH2 | 0.752949 | 3 | 0 | 3 |
| AIFM1 | DNMBP | 0.746238 | 3 | 0 | 3 |
| AIFM1 | ARFGAP2 | 0.746064 | 3 | 0 | 3 |
| AIFM1 | RRAGA | 0.739501 | 3 | 0 | 3 |
| AIFM1 | POLDIP3 | 0.738393 | 4 | 0 | 3 |
| AIFM1 | C21orf91 | 0.730033 | 3 | 0 | 3 |
| AIFM1 | THRAP3 | 0.729926 | 3 | 0 | 3 |
| AIFM1 | VPS18 | 0.729657 | 3 | 0 | 3 |
| AIFM1 | PRDX2 | 0.72641 | 3 | 0 | 3 |
| AIFM1 | ABCF1 | 0.725306 | 7 | 0 | 7 |
| AIFM1 | SMARCE1 | 0.722703 | 3 | 0 | 3 |
| AIFM1 | IMPACT | 0.720507 | 3 | 0 | 3 |
| AIFM1 | PLCD3 | 0.717014 | 3 | 0 | 3 |
| AIFM1 | SPNS1 | 0.712026 | 3 | 0 | 3 |
For details and further investigation, click here
