| Full name: cleavage and polyadenylation factor I subunit 1 | Alias Symbol: HEAB|hClp1 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 10978 | HGNC ID: HGNC:16999 | Ensembl Gene: ENSG00000172409 | OMIM ID: 608757 |
| Drug and gene relationship at DGIdb | |||
Expression of CLP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLP1 | 10978 | 204370_at | 0.5198 | 0.2844 | |
| GSE20347 | CLP1 | 10978 | 204370_at | 0.3456 | 0.0040 | |
| GSE23400 | CLP1 | 10978 | 204370_at | 0.3355 | 0.0000 | |
| GSE26886 | CLP1 | 10978 | 204370_at | -0.1607 | 0.5370 | |
| GSE29001 | CLP1 | 10978 | 204370_at | 0.1782 | 0.3713 | |
| GSE38129 | CLP1 | 10978 | 204370_at | 0.3763 | 0.0002 | |
| GSE45670 | CLP1 | 10978 | 204370_at | 0.2577 | 0.0284 | |
| GSE53622 | CLP1 | 10978 | 98916 | 0.3032 | 0.0019 | |
| GSE53624 | CLP1 | 10978 | 98916 | 0.1996 | 0.1622 | |
| GSE63941 | CLP1 | 10978 | 204370_at | 0.1264 | 0.7943 | |
| GSE77861 | CLP1 | 10978 | 204370_at | 0.3606 | 0.0703 | |
| GSE97050 | CLP1 | 10978 | A_24_P252973 | 0.1076 | 0.7135 | |
| SRP007169 | CLP1 | 10978 | RNAseq | -0.4045 | 0.2392 | |
| SRP008496 | CLP1 | 10978 | RNAseq | -0.2735 | 0.2248 | |
| SRP064894 | CLP1 | 10978 | RNAseq | -0.1812 | 0.1725 | |
| SRP133303 | CLP1 | 10978 | RNAseq | 0.2468 | 0.1260 | |
| SRP159526 | CLP1 | 10978 | RNAseq | -0.0861 | 0.6485 | |
| SRP193095 | CLP1 | 10978 | RNAseq | 0.0201 | 0.8726 | |
| SRP219564 | CLP1 | 10978 | RNAseq | -0.2324 | 0.4891 | |
| TCGA | CLP1 | 10978 | RNAseq | 0.0939 | 0.1439 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLP1 | 10978 | 2 | 3 | 25 | |
| GSE20123 | CLP1 | 10978 | 2 | 3 | 25 | |
| GSE43470 | CLP1 | 10978 | 1 | 5 | 37 | |
| GSE46452 | CLP1 | 10978 | 9 | 4 | 46 | |
| GSE47630 | CLP1 | 10978 | 3 | 8 | 29 | |
| GSE54993 | CLP1 | 10978 | 3 | 0 | 67 | |
| GSE54994 | CLP1 | 10978 | 5 | 6 | 42 | |
| GSE60625 | CLP1 | 10978 | 0 | 3 | 8 | |
| GSE74703 | CLP1 | 10978 | 1 | 3 | 32 | |
| GSE74704 | CLP1 | 10978 | 2 | 3 | 15 | |
| TCGA | CLP1 | 10978 | 14 | 10 | 72 |
Total number of gains: 42; Total number of losses: 48; Total Number of normals: 398.
Somatic mutations of CLP1:
Generating mutation plots.
Highly correlated genes for CLP1:
Showing top 20/1321 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLP1 | MRPL37 | 0.795228 | 4 | 0 | 4 |
| CLP1 | C18orf54 | 0.779645 | 3 | 0 | 3 |
| CLP1 | INTS12 | 0.76589 | 3 | 0 | 3 |
| CLP1 | UBE2L3 | 0.765863 | 3 | 0 | 3 |
| CLP1 | CHML | 0.765854 | 3 | 0 | 3 |
| CLP1 | SDHAF2 | 0.761677 | 7 | 0 | 7 |
| CLP1 | L3MBTL3 | 0.754748 | 3 | 0 | 3 |
| CLP1 | MAT2B | 0.751798 | 3 | 0 | 3 |
| CLP1 | CD163L1 | 0.740833 | 3 | 0 | 3 |
| CLP1 | KLHL13 | 0.737609 | 3 | 0 | 3 |
| CLP1 | ATP11C | 0.735655 | 3 | 0 | 3 |
| CLP1 | IDH3A | 0.734561 | 4 | 0 | 4 |
| CLP1 | C12orf73 | 0.734135 | 3 | 0 | 3 |
| CLP1 | KLHL5 | 0.73112 | 3 | 0 | 3 |
| CLP1 | TMEM69 | 0.728982 | 4 | 0 | 4 |
| CLP1 | RSBN1L | 0.728668 | 3 | 0 | 3 |
| CLP1 | UBP1 | 0.726973 | 4 | 0 | 4 |
| CLP1 | VPS33A | 0.725153 | 4 | 0 | 3 |
| CLP1 | PHOSPHO2 | 0.723548 | 3 | 0 | 3 |
| CLP1 | C15orf61 | 0.723052 | 3 | 0 | 3 |
For details and further investigation, click here
