| Full name: ubiquitin conjugating enzyme E2 M | Alias Symbol: hUbc12|UBC12 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 9040 | HGNC ID: HGNC:12491 | Ensembl Gene: ENSG00000130725 | OMIM ID: 603173 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UBE2M:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2M | 9040 | 203109_at | 0.1728 | 0.6435 | |
| GSE20347 | UBE2M | 9040 | 203109_at | -0.2999 | 0.2011 | |
| GSE23400 | UBE2M | 9040 | 203109_at | -0.1705 | 0.0135 | |
| GSE26886 | UBE2M | 9040 | 203109_at | -0.4174 | 0.2222 | |
| GSE29001 | UBE2M | 9040 | 203109_at | -0.4387 | 0.2484 | |
| GSE38129 | UBE2M | 9040 | 203109_at | -0.1097 | 0.6778 | |
| GSE45670 | UBE2M | 9040 | 203109_at | -0.4015 | 0.0437 | |
| GSE53622 | UBE2M | 9040 | 70717 | -0.3153 | 0.0000 | |
| GSE53624 | UBE2M | 9040 | 70717 | -0.2416 | 0.0122 | |
| GSE63941 | UBE2M | 9040 | 203109_at | 0.9718 | 0.0252 | |
| GSE77861 | UBE2M | 9040 | 203109_at | 0.0611 | 0.8570 | |
| GSE97050 | UBE2M | 9040 | A_23_P141847 | -0.0090 | 0.9775 | |
| SRP007169 | UBE2M | 9040 | RNAseq | -1.5164 | 0.0013 | |
| SRP008496 | UBE2M | 9040 | RNAseq | -1.1675 | 0.0000 | |
| SRP064894 | UBE2M | 9040 | RNAseq | 0.2112 | 0.4924 | |
| SRP133303 | UBE2M | 9040 | RNAseq | 0.1123 | 0.6084 | |
| SRP159526 | UBE2M | 9040 | RNAseq | 0.3786 | 0.0927 | |
| SRP193095 | UBE2M | 9040 | RNAseq | -0.0839 | 0.5393 | |
| SRP219564 | UBE2M | 9040 | RNAseq | 0.0919 | 0.7717 | |
| TCGA | UBE2M | 9040 | RNAseq | 0.0747 | 0.2292 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UBE2M expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2M:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2M | 9040 | 2 | 5 | 23 | |
| GSE20123 | UBE2M | 9040 | 2 | 4 | 24 | |
| GSE43470 | UBE2M | 9040 | 3 | 9 | 31 | |
| GSE46452 | UBE2M | 9040 | 45 | 1 | 13 | |
| GSE47630 | UBE2M | 9040 | 7 | 6 | 27 | |
| GSE54993 | UBE2M | 9040 | 18 | 4 | 48 | |
| GSE54994 | UBE2M | 9040 | 5 | 12 | 36 | |
| GSE60625 | UBE2M | 9040 | 9 | 0 | 2 | |
| GSE74703 | UBE2M | 9040 | 3 | 6 | 27 | |
| GSE74704 | UBE2M | 9040 | 2 | 1 | 17 | |
| TCGA | UBE2M | 9040 | 20 | 19 | 57 |
Total number of gains: 116; Total number of losses: 67; Total Number of normals: 305.
Somatic mutations of UBE2M:
Generating mutation plots.
Highly correlated genes for UBE2M:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2M | AKT1 | 0.784456 | 3 | 0 | 3 |
| UBE2M | CHMP7 | 0.762948 | 3 | 0 | 3 |
| UBE2M | SSH1 | 0.759846 | 3 | 0 | 3 |
| UBE2M | MCOLN1 | 0.718417 | 5 | 0 | 5 |
| UBE2M | ERCC2 | 0.714062 | 3 | 0 | 3 |
| UBE2M | CIB1 | 0.711569 | 3 | 0 | 3 |
| UBE2M | SNX20 | 0.70517 | 3 | 0 | 3 |
| UBE2M | MTCH2 | 0.703191 | 3 | 0 | 3 |
| UBE2M | MTO1 | 0.701766 | 3 | 0 | 3 |
| UBE2M | AP2B1 | 0.700309 | 3 | 0 | 3 |
| UBE2M | MRPL44 | 0.696489 | 4 | 0 | 3 |
| UBE2M | MAU2 | 0.69644 | 3 | 0 | 3 |
| UBE2M | MCTS1 | 0.696216 | 4 | 0 | 4 |
| UBE2M | LSM10 | 0.694391 | 4 | 0 | 4 |
| UBE2M | SLC25A24 | 0.694165 | 4 | 0 | 4 |
| UBE2M | PTGES2 | 0.688505 | 5 | 0 | 4 |
| UBE2M | PLA2G12A | 0.686137 | 4 | 0 | 4 |
| UBE2M | TAGAP | 0.683659 | 3 | 0 | 3 |
| UBE2M | CD37 | 0.683187 | 3 | 0 | 3 |
| UBE2M | ZNF41 | 0.682885 | 3 | 0 | 3 |
For details and further investigation, click here
