| Full name: chloride intracellular channel 5 | Alias Symbol: DFNB102 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 53405 | HGNC ID: HGNC:13517 | Ensembl Gene: ENSG00000112782 | OMIM ID: 607293 |
| Drug and gene relationship at DGIdb | |||
Expression of CLIC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLIC5 | 53405 | 219866_at | 0.1529 | 0.7450 | |
| GSE20347 | CLIC5 | 53405 | 219866_at | -0.0332 | 0.7447 | |
| GSE23400 | CLIC5 | 53405 | 219866_at | -0.1503 | 0.0000 | |
| GSE26886 | CLIC5 | 53405 | 219866_at | -0.0428 | 0.7224 | |
| GSE29001 | CLIC5 | 53405 | 219866_at | -0.0244 | 0.9177 | |
| GSE38129 | CLIC5 | 53405 | 219866_at | -0.2103 | 0.0320 | |
| GSE45670 | CLIC5 | 53405 | 219866_at | -0.3064 | 0.0061 | |
| GSE53622 | CLIC5 | 53405 | 71594 | -0.1471 | 0.1018 | |
| GSE53624 | CLIC5 | 53405 | 71594 | -0.1789 | 0.0077 | |
| GSE63941 | CLIC5 | 53405 | 219866_at | 0.2128 | 0.5116 | |
| GSE77861 | CLIC5 | 53405 | 219866_at | -0.1953 | 0.1057 | |
| GSE97050 | CLIC5 | 53405 | A_33_P3392177 | -0.0798 | 0.7206 | |
| SRP064894 | CLIC5 | 53405 | RNAseq | 0.2572 | 0.5125 | |
| SRP133303 | CLIC5 | 53405 | RNAseq | 0.0632 | 0.8805 | |
| SRP159526 | CLIC5 | 53405 | RNAseq | -0.2361 | 0.7207 | |
| SRP219564 | CLIC5 | 53405 | RNAseq | 0.2160 | 0.7219 | |
| TCGA | CLIC5 | 53405 | RNAseq | -0.9697 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLIC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLIC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLIC5 | 53405 | 6 | 2 | 22 | |
| GSE20123 | CLIC5 | 53405 | 6 | 2 | 22 | |
| GSE43470 | CLIC5 | 53405 | 6 | 0 | 37 | |
| GSE46452 | CLIC5 | 53405 | 2 | 10 | 47 | |
| GSE47630 | CLIC5 | 53405 | 8 | 5 | 27 | |
| GSE54993 | CLIC5 | 53405 | 3 | 1 | 66 | |
| GSE54994 | CLIC5 | 53405 | 8 | 3 | 42 | |
| GSE60625 | CLIC5 | 53405 | 0 | 3 | 8 | |
| GSE74703 | CLIC5 | 53405 | 6 | 0 | 30 | |
| GSE74704 | CLIC5 | 53405 | 2 | 1 | 17 | |
| TCGA | CLIC5 | 53405 | 17 | 15 | 64 |
Total number of gains: 64; Total number of losses: 42; Total Number of normals: 382.
Somatic mutations of CLIC5:
Generating mutation plots.
Highly correlated genes for CLIC5:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLIC5 | CPAMD8 | 0.75742 | 3 | 0 | 3 |
| CLIC5 | ING5 | 0.701056 | 3 | 0 | 3 |
| CLIC5 | PNMA6A | 0.678949 | 3 | 0 | 3 |
| CLIC5 | MORN3 | 0.667049 | 3 | 0 | 3 |
| CLIC5 | KCNA7 | 0.665921 | 3 | 0 | 3 |
| CLIC5 | KSR1 | 0.661206 | 4 | 0 | 4 |
| CLIC5 | KDM4C | 0.658722 | 3 | 0 | 3 |
| CLIC5 | NKAIN4 | 0.657333 | 3 | 0 | 3 |
| CLIC5 | TMPRSS15 | 0.648832 | 4 | 0 | 3 |
| CLIC5 | TMEM221 | 0.646025 | 3 | 0 | 3 |
| CLIC5 | LENG1 | 0.641226 | 3 | 0 | 3 |
| CLIC5 | PKDREJ | 0.641151 | 6 | 0 | 4 |
| CLIC5 | MAGEL2 | 0.637613 | 5 | 0 | 5 |
| CLIC5 | FTCDNL1 | 0.635132 | 3 | 0 | 3 |
| CLIC5 | AMELY | 0.633845 | 3 | 0 | 3 |
| CLIC5 | CHMP6 | 0.632918 | 3 | 0 | 3 |
| CLIC5 | GABRB1 | 0.632489 | 4 | 0 | 3 |
| CLIC5 | FASLG | 0.630553 | 6 | 0 | 6 |
| CLIC5 | CDK20 | 0.628561 | 4 | 0 | 3 |
| CLIC5 | RGP1 | 0.626644 | 4 | 0 | 3 |
For details and further investigation, click here
