| Full name: lysine demethylase 4C | Alias Symbol: GASC1|KIAA0780|TDRD14C | ||
| Type: protein-coding gene | Cytoband: 9p24.1 | ||
| Entrez ID: 23081 | HGNC ID: HGNC:17071 | Ensembl Gene: ENSG00000107077 | OMIM ID: 605469 |
| Drug and gene relationship at DGIdb | |||
Expression of KDM4C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KDM4C | 23081 | 209984_at | -0.4161 | 0.3685 | |
| GSE20347 | KDM4C | 23081 | 209984_at | -0.3667 | 0.0019 | |
| GSE23400 | KDM4C | 23081 | 209984_at | -0.0647 | 0.3009 | |
| GSE26886 | KDM4C | 23081 | 209984_at | -0.2595 | 0.2751 | |
| GSE29001 | KDM4C | 23081 | 214861_at | -0.2987 | 0.2260 | |
| GSE38129 | KDM4C | 23081 | 209984_at | -0.3564 | 0.0206 | |
| GSE45670 | KDM4C | 23081 | 209984_at | -0.3874 | 0.0034 | |
| GSE53622 | KDM4C | 23081 | 121111 | -0.4810 | 0.0000 | |
| GSE53624 | KDM4C | 23081 | 121111 | -0.2709 | 0.0000 | |
| GSE63941 | KDM4C | 23081 | 209984_at | -0.9151 | 0.1952 | |
| GSE77861 | KDM4C | 23081 | 209984_at | -0.2103 | 0.1914 | |
| GSE97050 | KDM4C | 23081 | A_23_P112201 | -0.0777 | 0.6828 | |
| SRP007169 | KDM4C | 23081 | RNAseq | -0.4949 | 0.2561 | |
| SRP008496 | KDM4C | 23081 | RNAseq | -0.3565 | 0.2157 | |
| SRP064894 | KDM4C | 23081 | RNAseq | -0.2484 | 0.2342 | |
| SRP133303 | KDM4C | 23081 | RNAseq | -0.4477 | 0.0047 | |
| SRP159526 | KDM4C | 23081 | RNAseq | -0.7854 | 0.0045 | |
| SRP193095 | KDM4C | 23081 | RNAseq | -0.5811 | 0.0003 | |
| SRP219564 | KDM4C | 23081 | RNAseq | -0.3022 | 0.2428 | |
| TCGA | KDM4C | 23081 | RNAseq | -0.2558 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KDM4C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KDM4C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KDM4C | 23081 | 1 | 17 | 12 | |
| GSE20123 | KDM4C | 23081 | 1 | 17 | 12 | |
| GSE43470 | KDM4C | 23081 | 5 | 12 | 26 | |
| GSE46452 | KDM4C | 23081 | 2 | 23 | 34 | |
| GSE47630 | KDM4C | 23081 | 5 | 26 | 9 | |
| GSE54993 | KDM4C | 23081 | 6 | 3 | 61 | |
| GSE54994 | KDM4C | 23081 | 9 | 16 | 28 | |
| GSE60625 | KDM4C | 23081 | 0 | 2 | 9 | |
| GSE74703 | KDM4C | 23081 | 5 | 9 | 22 | |
| GSE74704 | KDM4C | 23081 | 0 | 13 | 7 | |
| TCGA | KDM4C | 23081 | 15 | 50 | 31 |
Total number of gains: 49; Total number of losses: 188; Total Number of normals: 251.
Somatic mutations of KDM4C:
Generating mutation plots.
Highly correlated genes for KDM4C:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KDM4C | KIAA2026 | 0.728916 | 6 | 0 | 6 |
| KDM4C | CLIC5 | 0.658722 | 3 | 0 | 3 |
| KDM4C | ZADH2 | 0.654809 | 5 | 0 | 5 |
| KDM4C | METTL25 | 0.644792 | 5 | 0 | 4 |
| KDM4C | CDC37L1 | 0.63443 | 11 | 0 | 10 |
| KDM4C | GABARAP | 0.624683 | 4 | 0 | 4 |
| KDM4C | RPS6 | 0.615738 | 8 | 0 | 7 |
| KDM4C | ELAC1 | 0.613137 | 3 | 0 | 3 |
| KDM4C | NFX1 | 0.613089 | 4 | 0 | 4 |
| KDM4C | FBXO8 | 0.610022 | 5 | 0 | 4 |
| KDM4C | ARMC4 | 0.604315 | 3 | 0 | 3 |
| KDM4C | ERP44 | 0.59997 | 3 | 0 | 3 |
| KDM4C | BAG1 | 0.596437 | 6 | 0 | 4 |
| KDM4C | CREBRF | 0.593022 | 4 | 0 | 3 |
| KDM4C | MAP3K3 | 0.587896 | 4 | 0 | 3 |
| KDM4C | NUDT2 | 0.582657 | 6 | 0 | 4 |
| KDM4C | FOCAD | 0.582519 | 10 | 0 | 5 |
| KDM4C | SUCLA2 | 0.581677 | 5 | 0 | 3 |
| KDM4C | METTL2B | 0.579678 | 3 | 0 | 3 |
| KDM4C | LRRK2 | 0.578226 | 4 | 0 | 3 |
For details and further investigation, click here
