| Full name: RGP1 homolog, RAB6A GEF complex partner 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p13.3 | ||
| Entrez ID: 9827 | HGNC ID: HGNC:21965 | Ensembl Gene: ENSG00000107185 | OMIM ID: 615742 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RGP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGP1 | 9827 | 203169_at | 0.1589 | 0.5400 | |
| GSE20347 | RGP1 | 9827 | 203169_at | -0.2527 | 0.0507 | |
| GSE23400 | RGP1 | 9827 | 203169_at | -0.0198 | 0.5955 | |
| GSE26886 | RGP1 | 9827 | 203169_at | -0.0471 | 0.8680 | |
| GSE29001 | RGP1 | 9827 | 203169_at | 0.3256 | 0.2521 | |
| GSE38129 | RGP1 | 9827 | 203169_at | -0.1990 | 0.0571 | |
| GSE45670 | RGP1 | 9827 | 203169_at | 0.1160 | 0.3795 | |
| GSE53622 | RGP1 | 9827 | 60229 | -0.3393 | 0.0000 | |
| GSE53624 | RGP1 | 9827 | 60229 | -0.1572 | 0.0071 | |
| GSE63941 | RGP1 | 9827 | 203169_at | -0.1159 | 0.7993 | |
| GSE77861 | RGP1 | 9827 | 203169_at | -0.1979 | 0.2530 | |
| GSE97050 | RGP1 | 9827 | A_24_P398064 | -0.1662 | 0.4339 | |
| SRP007169 | RGP1 | 9827 | RNAseq | 0.1602 | 0.7003 | |
| SRP008496 | RGP1 | 9827 | RNAseq | 0.0920 | 0.7046 | |
| SRP064894 | RGP1 | 9827 | RNAseq | 0.2247 | 0.0438 | |
| SRP133303 | RGP1 | 9827 | RNAseq | -0.2241 | 0.1867 | |
| SRP159526 | RGP1 | 9827 | RNAseq | -0.6405 | 0.0015 | |
| SRP193095 | RGP1 | 9827 | RNAseq | 0.1273 | 0.4687 | |
| SRP219564 | RGP1 | 9827 | RNAseq | 0.1003 | 0.7612 | |
| TCGA | RGP1 | 9827 | RNAseq | -0.2709 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RGP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGP1 | 9827 | 3 | 12 | 15 | |
| GSE20123 | RGP1 | 9827 | 3 | 12 | 15 | |
| GSE43470 | RGP1 | 9827 | 3 | 10 | 30 | |
| GSE46452 | RGP1 | 9827 | 6 | 15 | 38 | |
| GSE47630 | RGP1 | 9827 | 1 | 20 | 19 | |
| GSE54993 | RGP1 | 9827 | 6 | 0 | 64 | |
| GSE54994 | RGP1 | 9827 | 5 | 12 | 36 | |
| GSE60625 | RGP1 | 9827 | 0 | 0 | 11 | |
| GSE74703 | RGP1 | 9827 | 2 | 7 | 27 | |
| GSE74704 | RGP1 | 9827 | 0 | 10 | 10 | |
| TCGA | RGP1 | 9827 | 17 | 44 | 35 |
Total number of gains: 46; Total number of losses: 142; Total Number of normals: 300.
Somatic mutations of RGP1:
Generating mutation plots.
Highly correlated genes for RGP1:
Showing top 20/62 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGP1 | ZNF444 | 0.761334 | 3 | 0 | 3 |
| RGP1 | TMEM63A | 0.7468 | 3 | 0 | 3 |
| RGP1 | ABCA2 | 0.723243 | 3 | 0 | 3 |
| RGP1 | HOXB9 | 0.705634 | 3 | 0 | 3 |
| RGP1 | AGAP2 | 0.703995 | 3 | 0 | 3 |
| RGP1 | MAGEE1 | 0.699725 | 3 | 0 | 3 |
| RGP1 | INF2 | 0.699206 | 3 | 0 | 3 |
| RGP1 | HSD17B14 | 0.697644 | 3 | 0 | 3 |
| RGP1 | LIM2 | 0.694152 | 3 | 0 | 3 |
| RGP1 | TBX4 | 0.690754 | 3 | 0 | 3 |
| RGP1 | RAD52 | 0.683209 | 3 | 0 | 3 |
| RGP1 | GNL1 | 0.671963 | 3 | 0 | 3 |
| RGP1 | CA4 | 0.671768 | 3 | 0 | 3 |
| RGP1 | PTGDR2 | 0.662987 | 4 | 0 | 3 |
| RGP1 | NKX2-8 | 0.660916 | 3 | 0 | 3 |
| RGP1 | ARVCF | 0.660856 | 4 | 0 | 3 |
| RGP1 | SLC18A3 | 0.655132 | 4 | 0 | 4 |
| RGP1 | CELA3B | 0.653424 | 4 | 0 | 3 |
| RGP1 | NACAD | 0.64869 | 4 | 0 | 3 |
| RGP1 | LRCH4 | 0.648603 | 4 | 0 | 3 |
For details and further investigation, click here
