GTSE1

 

Full name: G2 and S-phase expressed 1 Alias Symbol: GTSE-1|B99
Type: protein-coding gene Cytoband: 22q13.31
Entrez ID: 51512 HGNC ID: HGNC:13698 Ensembl Gene: ENSG00000075218 OMIM ID: 607477
Drug and gene relationship at DGIdb
Screen Evidence:

 

GTSE1 involved pathways:

KEGG pathway Description View
hsa04115p53 signaling pathway

 

Expression of GTSE1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GTSE1 51512 211040_x_at 0.6948 0.1188
GSE20347 GTSE1 51512 211040_x_at 0.5292 0.0001
GSE23400 GTSE1 51512 211040_x_at 0.2757 0.0000
GSE26886 GTSE1 51512 211040_x_at 0.7399 0.0002
GSE29001 GTSE1 51512 211040_x_at 0.6236 0.0079
GSE38129 GTSE1 51512 211040_x_at 0.6066 0.0000
GSE45670 GTSE1 51512 211040_x_at 0.3680 0.0015
GSE53622 GTSE1 51512 2264 2.2058 0.0000
GSE53624 GTSE1 51512 2264 2.2625 0.0000
GSE63941 GTSE1 51512 211040_x_at 0.2508 0.3901
GSE77861 GTSE1 51512 211040_x_at 0.6048 0.0082
GSE97050 GTSE1 51512 A_23_P57588 1.2930 0.1344
SRP007169 GTSE1 51512 RNAseq 2.2553 0.0001
SRP008496 GTSE1 51512 RNAseq 2.2377 0.0000
SRP064894 GTSE1 51512 RNAseq 2.1505 0.0000
SRP133303 GTSE1 51512 RNAseq 1.3848 0.0000
SRP159526 GTSE1 51512 RNAseq 1.7642 0.0001
SRP193095 GTSE1 51512 RNAseq 0.9642 0.0000
SRP219564 GTSE1 51512 RNAseq 1.4887 0.0458
TCGA GTSE1 51512 RNAseq 1.2374 0.0000

Upregulated datasets: 9; Downregulated datasets: 0.  

 

Survival by GTSE1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GTSE1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GTSE1 51512 5 6 19
GSE20123 GTSE1 51512 4 5 21
GSE43470 GTSE1 51512 2 6 35
GSE46452 GTSE1 51512 31 2 26
GSE47630 GTSE1 51512 9 4 27
GSE54993 GTSE1 51512 3 6 61
GSE54994 GTSE1 51512 11 7 35
GSE60625 GTSE1 51512 5 0 6
GSE74703 GTSE1 51512 2 4 30
GSE74704 GTSE1 51512 2 3 15
TCGA GTSE1 51512 27 15 54

Total number of gains: 101; Total number of losses: 58; Total Number of normals: 329.  

 

Somatic mutations of GTSE1:

 

Generating mutation plots.

 

Highly correlated genes for GTSE1:

 

Showing top 20/1744 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GTSE1CMBL0.860729404
GTSE1PRR110.84587112011
GTSE1ZNF7210.826521808
GTSE1MZT2B0.810699909
GTSE1KLHL240.782844707
GTSE1MTBP0.775212505
GTSE1SH2B20.772268909
GTSE1ZNF1600.76835808
GTSE1PNPT10.76472606
GTSE1SLC35E10.76303908
GTSE1NLN0.762879707
GTSE1DKC10.754101303
GTSE1UHRF10.75045808
GTSE1FUT8-AS10.749657404
GTSE1CMSS10.74384606
GTSE1DDX590.740355504
GTSE1ZNF6110.739284808
GTSE1ORC60.73853811011
GTSE1MMS22L0.736993303
GTSE1NOP580.736034707

For details and further investigation, click here