| Full name: trinucleotide repeat containing adaptor 6A | Alias Symbol: CAGH26|KIAA1460|GW182 | ||
| Type: protein-coding gene | Cytoband: 16p12.1 | ||
| Entrez ID: 27327 | HGNC ID: HGNC:11969 | Ensembl Gene: ENSG00000090905 | OMIM ID: 610739 |
| Drug and gene relationship at DGIdb | |||
Expression of TNRC6A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNRC6A | 27327 | 224705_s_at | -0.1383 | 0.7029 | |
| GSE26886 | TNRC6A | 27327 | 224704_at | -0.2204 | 0.4014 | |
| GSE45670 | TNRC6A | 27327 | 224705_s_at | -0.0760 | 0.6001 | |
| GSE53622 | TNRC6A | 27327 | 35338 | -0.1593 | 0.0078 | |
| GSE53624 | TNRC6A | 27327 | 35338 | -0.0900 | 0.0950 | |
| GSE63941 | TNRC6A | 27327 | 224705_s_at | -0.8029 | 0.0133 | |
| GSE77861 | TNRC6A | 27327 | 224704_at | -0.0495 | 0.8852 | |
| GSE97050 | TNRC6A | 27327 | A_23_P349310 | -0.2167 | 0.3456 | |
| SRP007169 | TNRC6A | 27327 | RNAseq | 0.0367 | 0.9200 | |
| SRP008496 | TNRC6A | 27327 | RNAseq | 0.0886 | 0.6654 | |
| SRP064894 | TNRC6A | 27327 | RNAseq | -0.5856 | 0.0132 | |
| SRP133303 | TNRC6A | 27327 | RNAseq | 0.0111 | 0.9091 | |
| SRP159526 | TNRC6A | 27327 | RNAseq | 0.0417 | 0.8980 | |
| SRP193095 | TNRC6A | 27327 | RNAseq | 0.0238 | 0.8233 | |
| SRP219564 | TNRC6A | 27327 | RNAseq | -0.2884 | 0.2530 | |
| TCGA | TNRC6A | 27327 | RNAseq | -0.1194 | 0.0065 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNRC6A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNRC6A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNRC6A | 27327 | 4 | 4 | 22 | |
| GSE20123 | TNRC6A | 27327 | 4 | 3 | 23 | |
| GSE43470 | TNRC6A | 27327 | 4 | 3 | 36 | |
| GSE46452 | TNRC6A | 27327 | 38 | 1 | 20 | |
| GSE47630 | TNRC6A | 27327 | 11 | 6 | 23 | |
| GSE54993 | TNRC6A | 27327 | 3 | 5 | 62 | |
| GSE54994 | TNRC6A | 27327 | 4 | 9 | 40 | |
| GSE60625 | TNRC6A | 27327 | 4 | 0 | 7 | |
| GSE74703 | TNRC6A | 27327 | 4 | 2 | 30 | |
| GSE74704 | TNRC6A | 27327 | 2 | 1 | 17 | |
| TCGA | TNRC6A | 27327 | 19 | 13 | 64 |
Total number of gains: 97; Total number of losses: 47; Total Number of normals: 344.
Somatic mutations of TNRC6A:
Generating mutation plots.
Highly correlated genes for TNRC6A:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNRC6A | NUDT19 | 0.761567 | 3 | 0 | 3 |
| TNRC6A | B4GALT5 | 0.739031 | 3 | 0 | 3 |
| TNRC6A | COG1 | 0.737692 | 3 | 0 | 3 |
| TNRC6A | RNASEL | 0.732904 | 3 | 0 | 3 |
| TNRC6A | EIF4G3 | 0.729366 | 4 | 0 | 4 |
| TNRC6A | PURA | 0.725341 | 3 | 0 | 3 |
| TNRC6A | C6orf120 | 0.722604 | 3 | 0 | 3 |
| TNRC6A | ADHFE1 | 0.715455 | 3 | 0 | 3 |
| TNRC6A | DCTN4 | 0.712031 | 3 | 0 | 3 |
| TNRC6A | PPP1R15B | 0.711138 | 3 | 0 | 3 |
| TNRC6A | SCAF8 | 0.710825 | 4 | 0 | 3 |
| TNRC6A | NBR1 | 0.710624 | 3 | 0 | 3 |
| TNRC6A | RXRA | 0.706477 | 3 | 0 | 3 |
| TNRC6A | MRPS10 | 0.705223 | 3 | 0 | 3 |
| TNRC6A | MTPN | 0.699983 | 3 | 0 | 3 |
| TNRC6A | PTAR1 | 0.698436 | 4 | 0 | 3 |
| TNRC6A | TMED2 | 0.693465 | 3 | 0 | 3 |
| TNRC6A | ZNF764 | 0.69181 | 3 | 0 | 3 |
| TNRC6A | EZH1 | 0.689097 | 4 | 0 | 4 |
| TNRC6A | NR2C1 | 0.688633 | 4 | 0 | 3 |
For details and further investigation, click here
