| Full name: CASK interacting protein 2 | Alias Symbol: KIAA1139|FLJ21609|ANKS5B | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 57513 | HGNC ID: HGNC:18200 | Ensembl Gene: ENSG00000177303 | OMIM ID: 612185 |
| Drug and gene relationship at DGIdb | |||
Expression of CASKIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CASKIN2 | 57513 | 221846_s_at | 0.3326 | 0.7382 | |
| GSE20347 | CASKIN2 | 57513 | 221846_s_at | 0.0610 | 0.4163 | |
| GSE23400 | CASKIN2 | 57513 | 221846_s_at | -0.0218 | 0.6423 | |
| GSE26886 | CASKIN2 | 57513 | 221846_s_at | 0.2622 | 0.0395 | |
| GSE29001 | CASKIN2 | 57513 | 221846_s_at | -0.1058 | 0.5269 | |
| GSE38129 | CASKIN2 | 57513 | 221846_s_at | -0.1795 | 0.2472 | |
| GSE45670 | CASKIN2 | 57513 | 221846_s_at | -0.0655 | 0.6274 | |
| GSE53622 | CASKIN2 | 57513 | 36758 | -0.4063 | 0.0000 | |
| GSE53624 | CASKIN2 | 57513 | 36758 | -0.1730 | 0.0186 | |
| GSE63941 | CASKIN2 | 57513 | 221846_s_at | 0.1304 | 0.6489 | |
| GSE77861 | CASKIN2 | 57513 | 221846_s_at | 0.1074 | 0.7521 | |
| GSE97050 | CASKIN2 | 57513 | A_23_P44363 | -0.0908 | 0.8482 | |
| SRP007169 | CASKIN2 | 57513 | RNAseq | 0.9421 | 0.0808 | |
| SRP064894 | CASKIN2 | 57513 | RNAseq | -0.1652 | 0.3878 | |
| SRP133303 | CASKIN2 | 57513 | RNAseq | -0.1439 | 0.5848 | |
| SRP159526 | CASKIN2 | 57513 | RNAseq | 0.1344 | 0.5044 | |
| SRP193095 | CASKIN2 | 57513 | RNAseq | 0.3115 | 0.0527 | |
| SRP219564 | CASKIN2 | 57513 | RNAseq | 0.0091 | 0.9858 | |
| TCGA | CASKIN2 | 57513 | RNAseq | -0.2178 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CASKIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CASKIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CASKIN2 | 57513 | 6 | 2 | 22 | |
| GSE20123 | CASKIN2 | 57513 | 6 | 2 | 22 | |
| GSE43470 | CASKIN2 | 57513 | 5 | 3 | 35 | |
| GSE46452 | CASKIN2 | 57513 | 34 | 0 | 25 | |
| GSE47630 | CASKIN2 | 57513 | 8 | 1 | 31 | |
| GSE54993 | CASKIN2 | 57513 | 2 | 5 | 63 | |
| GSE54994 | CASKIN2 | 57513 | 10 | 4 | 39 | |
| GSE60625 | CASKIN2 | 57513 | 6 | 0 | 5 | |
| GSE74703 | CASKIN2 | 57513 | 5 | 1 | 30 | |
| GSE74704 | CASKIN2 | 57513 | 4 | 1 | 15 | |
| TCGA | CASKIN2 | 57513 | 32 | 10 | 54 |
Total number of gains: 118; Total number of losses: 29; Total Number of normals: 341.
Somatic mutations of CASKIN2:
Generating mutation plots.
Highly correlated genes for CASKIN2:
Showing top 20/454 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CASKIN2 | NSD1 | 0.847684 | 3 | 0 | 3 |
| CASKIN2 | COG1 | 0.797278 | 3 | 0 | 3 |
| CASKIN2 | DEDD | 0.792475 | 3 | 0 | 3 |
| CASKIN2 | GCDH | 0.787141 | 3 | 0 | 3 |
| CASKIN2 | HECTD3 | 0.783534 | 3 | 0 | 3 |
| CASKIN2 | CHCHD6 | 0.779909 | 3 | 0 | 3 |
| CASKIN2 | FIBCD1 | 0.779796 | 3 | 0 | 3 |
| CASKIN2 | RSBN1L | 0.774752 | 3 | 0 | 3 |
| CASKIN2 | CCDC124 | 0.774591 | 4 | 0 | 4 |
| CASKIN2 | GYG2 | 0.771569 | 3 | 0 | 3 |
| CASKIN2 | FCHO1 | 0.767219 | 3 | 0 | 3 |
| CASKIN2 | UBA52 | 0.756682 | 3 | 0 | 3 |
| CASKIN2 | PACS1 | 0.75053 | 4 | 0 | 4 |
| CASKIN2 | PREX2 | 0.747431 | 3 | 0 | 3 |
| CASKIN2 | ZNF641 | 0.742615 | 4 | 0 | 4 |
| CASKIN2 | NFAM1 | 0.739649 | 3 | 0 | 3 |
| CASKIN2 | STAT5B | 0.731605 | 3 | 0 | 3 |
| CASKIN2 | KANSL3 | 0.730987 | 3 | 0 | 3 |
| CASKIN2 | C9orf16 | 0.726357 | 4 | 0 | 4 |
| CASKIN2 | R3HDM2 | 0.72605 | 3 | 0 | 3 |
For details and further investigation, click here
