| Full name: STIP1 homology and U-box containing protein 1 | Alias Symbol: UBOX1|CHIP|SDCCAG7|HSPABP2|NY-CO-7 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 10273 | HGNC ID: HGNC:11427 | Ensembl Gene: ENSG00000103266 | OMIM ID: 607207 |
| Drug and gene relationship at DGIdb | |||
Expression of STUB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STUB1 | 10273 | 227625_s_at | 0.0436 | 0.9376 | |
| GSE20347 | STUB1 | 10273 | 217934_x_at | -0.2251 | 0.0322 | |
| GSE23400 | STUB1 | 10273 | 217934_x_at | -0.0550 | 0.3722 | |
| GSE26886 | STUB1 | 10273 | 227625_s_at | 0.0061 | 0.9744 | |
| GSE29001 | STUB1 | 10273 | 217934_x_at | -0.3034 | 0.2015 | |
| GSE38129 | STUB1 | 10273 | 217934_x_at | -0.2525 | 0.0155 | |
| GSE45670 | STUB1 | 10273 | 227625_s_at | -0.1033 | 0.3071 | |
| GSE63941 | STUB1 | 10273 | 227625_s_at | -0.0880 | 0.7454 | |
| GSE77861 | STUB1 | 10273 | 227625_s_at | 0.0107 | 0.9671 | |
| GSE97050 | STUB1 | 10273 | A_23_P37870 | -0.0625 | 0.8162 | |
| SRP007169 | STUB1 | 10273 | RNAseq | -1.0767 | 0.0056 | |
| SRP008496 | STUB1 | 10273 | RNAseq | -0.9031 | 0.0011 | |
| SRP064894 | STUB1 | 10273 | RNAseq | -0.1492 | 0.6419 | |
| SRP133303 | STUB1 | 10273 | RNAseq | -0.1158 | 0.3988 | |
| SRP159526 | STUB1 | 10273 | RNAseq | -0.1784 | 0.5121 | |
| SRP193095 | STUB1 | 10273 | RNAseq | -0.2405 | 0.0428 | |
| SRP219564 | STUB1 | 10273 | RNAseq | -0.1683 | 0.6257 | |
| TCGA | STUB1 | 10273 | RNAseq | -0.0719 | 0.1324 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by STUB1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of STUB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STUB1 | 10273 | 5 | 5 | 20 | |
| GSE20123 | STUB1 | 10273 | 5 | 4 | 21 | |
| GSE43470 | STUB1 | 10273 | 4 | 7 | 32 | |
| GSE46452 | STUB1 | 10273 | 38 | 1 | 20 | |
| GSE47630 | STUB1 | 10273 | 13 | 6 | 21 | |
| GSE54993 | STUB1 | 10273 | 3 | 5 | 62 | |
| GSE54994 | STUB1 | 10273 | 5 | 9 | 39 | |
| GSE60625 | STUB1 | 10273 | 4 | 0 | 7 | |
| GSE74703 | STUB1 | 10273 | 4 | 5 | 27 | |
| GSE74704 | STUB1 | 10273 | 3 | 2 | 15 | |
| TCGA | STUB1 | 10273 | 20 | 15 | 61 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of STUB1:
Generating mutation plots.
Highly correlated genes for STUB1:
Showing top 20/337 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STUB1 | RSBN1L | 0.795102 | 3 | 0 | 3 |
| STUB1 | PTPRU | 0.7754 | 3 | 0 | 3 |
| STUB1 | MAP2K5 | 0.773007 | 3 | 0 | 3 |
| STUB1 | COG1 | 0.761352 | 3 | 0 | 3 |
| STUB1 | WASL | 0.759288 | 3 | 0 | 3 |
| STUB1 | ATP6V0B | 0.740557 | 3 | 0 | 3 |
| STUB1 | IFNAR1 | 0.737475 | 3 | 0 | 3 |
| STUB1 | AP4M1 | 0.735198 | 3 | 0 | 3 |
| STUB1 | MED26 | 0.733073 | 3 | 0 | 3 |
| STUB1 | MRPS18A | 0.728099 | 3 | 0 | 3 |
| STUB1 | POLR3GL | 0.727949 | 3 | 0 | 3 |
| STUB1 | EEFSEC | 0.717398 | 3 | 0 | 3 |
| STUB1 | TCEANC2 | 0.715822 | 3 | 0 | 3 |
| STUB1 | CIB1 | 0.710143 | 4 | 0 | 3 |
| STUB1 | LUC7L2 | 0.707636 | 3 | 0 | 3 |
| STUB1 | STOML1 | 0.706212 | 4 | 0 | 4 |
| STUB1 | ZNHIT1 | 0.703938 | 4 | 0 | 3 |
| STUB1 | NDUFB4 | 0.702225 | 3 | 0 | 3 |
| STUB1 | FASTKD2 | 0.701904 | 3 | 0 | 3 |
| STUB1 | TCTN1 | 0.700909 | 3 | 0 | 3 |
For details and further investigation, click here
