| Full name: phosphodiesterase 6H | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 5149 | HGNC ID: HGNC:8790 | Ensembl Gene: ENSG00000139053 | OMIM ID: 601190 |
| Drug and gene relationship at DGIdb | |||
Expression of PDE6H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDE6H | 5149 | 206841_at | 0.0177 | 0.9516 | |
| GSE20347 | PDE6H | 5149 | 206841_at | -0.0642 | 0.1569 | |
| GSE23400 | PDE6H | 5149 | 206841_at | -0.0714 | 0.0055 | |
| GSE26886 | PDE6H | 5149 | 206841_at | 0.1181 | 0.2070 | |
| GSE29001 | PDE6H | 5149 | 206841_at | -0.1594 | 0.1984 | |
| GSE38129 | PDE6H | 5149 | 206841_at | -0.1145 | 0.0128 | |
| GSE45670 | PDE6H | 5149 | 206841_at | 0.0433 | 0.6431 | |
| GSE63941 | PDE6H | 5149 | 206841_at | 0.0688 | 0.5581 | |
| GSE77861 | PDE6H | 5149 | 206841_at | -0.0154 | 0.8429 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDE6H expression:
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| TCGA |
Note: Click image to view full size file.
Copy number change of PDE6H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDE6H | 5149 | 6 | 2 | 22 | |
| GSE20123 | PDE6H | 5149 | 6 | 2 | 22 | |
| GSE43470 | PDE6H | 5149 | 9 | 4 | 30 | |
| GSE46452 | PDE6H | 5149 | 10 | 1 | 48 | |
| GSE47630 | PDE6H | 5149 | 14 | 1 | 25 | |
| GSE54993 | PDE6H | 5149 | 1 | 9 | 60 | |
| GSE54994 | PDE6H | 5149 | 10 | 2 | 41 | |
| GSE60625 | PDE6H | 5149 | 0 | 1 | 10 | |
| GSE74703 | PDE6H | 5149 | 9 | 3 | 24 | |
| GSE74704 | PDE6H | 5149 | 4 | 1 | 15 | |
| TCGA | PDE6H | 5149 | 41 | 5 | 50 |
Total number of gains: 110; Total number of losses: 31; Total Number of normals: 347.
Somatic mutations of PDE6H:
Generating mutation plots.
Highly correlated genes for PDE6H:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDE6H | EDDM3A | 0.705703 | 3 | 0 | 3 |
| PDE6H | RSPH6A | 0.675881 | 3 | 0 | 3 |
| PDE6H | SCGN | 0.675386 | 3 | 0 | 3 |
| PDE6H | TEX13A | 0.674936 | 4 | 0 | 4 |
| PDE6H | CTRC | 0.666744 | 4 | 0 | 4 |
| PDE6H | TAPT1 | 0.665775 | 4 | 0 | 4 |
| PDE6H | VWA5B2 | 0.662543 | 3 | 0 | 3 |
| PDE6H | KANSL3 | 0.660564 | 3 | 0 | 3 |
| PDE6H | VIP | 0.658456 | 3 | 0 | 3 |
| PDE6H | STXBP5L | 0.658137 | 3 | 0 | 3 |
| PDE6H | CHRM2 | 0.656491 | 5 | 0 | 4 |
| PDE6H | KIR2DS3 | 0.655439 | 5 | 0 | 3 |
| PDE6H | SST | 0.654655 | 4 | 0 | 4 |
| PDE6H | BTNL2 | 0.651155 | 4 | 0 | 4 |
| PDE6H | ZMAT4 | 0.649418 | 3 | 0 | 3 |
| PDE6H | SLC6A12 | 0.648956 | 3 | 0 | 3 |
| PDE6H | TTR | 0.646825 | 4 | 0 | 3 |
| PDE6H | NOX1 | 0.646609 | 4 | 0 | 3 |
| PDE6H | FBP2 | 0.644149 | 4 | 0 | 4 |
| PDE6H | NEUROD4 | 0.643167 | 4 | 0 | 3 |
For details and further investigation, click here
