| Full name: RPGR interacting protein 1 | Alias Symbol: RGI1|LCA6|CORD13 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 57096 | HGNC ID: HGNC:13436 | Ensembl Gene: ENSG00000092200 | OMIM ID: 605446 |
| Drug and gene relationship at DGIdb | |||
Expression of RPGRIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPGRIP1 | 57096 | 206608_s_at | 0.1271 | 0.7049 | |
| GSE20347 | RPGRIP1 | 57096 | 206608_s_at | 0.0829 | 0.3144 | |
| GSE23400 | RPGRIP1 | 57096 | 206608_s_at | -0.1071 | 0.0016 | |
| GSE26886 | RPGRIP1 | 57096 | 206608_s_at | 0.0910 | 0.5278 | |
| GSE29001 | RPGRIP1 | 57096 | 206608_s_at | 0.0206 | 0.9077 | |
| GSE38129 | RPGRIP1 | 57096 | 206608_s_at | -0.0375 | 0.5702 | |
| GSE45670 | RPGRIP1 | 57096 | 206608_s_at | 0.0910 | 0.2917 | |
| GSE53622 | RPGRIP1 | 57096 | 125237 | 0.3686 | 0.0005 | |
| GSE53624 | RPGRIP1 | 57096 | 125237 | 0.2839 | 0.0004 | |
| GSE63941 | RPGRIP1 | 57096 | 206608_s_at | 0.0802 | 0.5671 | |
| GSE77861 | RPGRIP1 | 57096 | 206608_s_at | 0.4514 | 0.5933 | |
| SRP133303 | RPGRIP1 | 57096 | RNAseq | -0.6729 | 0.0406 | |
| TCGA | RPGRIP1 | 57096 | RNAseq | 0.6523 | 0.2555 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPGRIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPGRIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPGRIP1 | 57096 | 9 | 3 | 18 | |
| GSE20123 | RPGRIP1 | 57096 | 9 | 3 | 18 | |
| GSE43470 | RPGRIP1 | 57096 | 7 | 2 | 34 | |
| GSE46452 | RPGRIP1 | 57096 | 19 | 2 | 38 | |
| GSE47630 | RPGRIP1 | 57096 | 10 | 10 | 20 | |
| GSE54993 | RPGRIP1 | 57096 | 3 | 11 | 56 | |
| GSE54994 | RPGRIP1 | 57096 | 18 | 5 | 30 | |
| GSE60625 | RPGRIP1 | 57096 | 0 | 2 | 9 | |
| GSE74703 | RPGRIP1 | 57096 | 6 | 2 | 28 | |
| GSE74704 | RPGRIP1 | 57096 | 4 | 2 | 14 | |
| TCGA | RPGRIP1 | 57096 | 27 | 16 | 53 |
Total number of gains: 112; Total number of losses: 58; Total Number of normals: 318.
Somatic mutations of RPGRIP1:
Generating mutation plots.
Highly correlated genes for RPGRIP1:
Showing top 20/574 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPGRIP1 | STXBP6 | 0.77828 | 3 | 0 | 3 |
| RPGRIP1 | ZMAT4 | 0.755747 | 3 | 0 | 3 |
| RPGRIP1 | GPA33 | 0.744368 | 4 | 0 | 4 |
| RPGRIP1 | HRG | 0.736808 | 4 | 0 | 4 |
| RPGRIP1 | OR1F1 | 0.735424 | 4 | 0 | 4 |
| RPGRIP1 | CYP2D6 | 0.725993 | 4 | 0 | 4 |
| RPGRIP1 | CHRM2 | 0.713988 | 4 | 0 | 4 |
| RPGRIP1 | IFNA7 | 0.705593 | 5 | 0 | 5 |
| RPGRIP1 | GAD2 | 0.704436 | 4 | 0 | 4 |
| RPGRIP1 | DNMT3L | 0.698156 | 3 | 0 | 3 |
| RPGRIP1 | LENEP | 0.69425 | 5 | 0 | 5 |
| RPGRIP1 | KCNN1 | 0.69154 | 6 | 0 | 6 |
| RPGRIP1 | SGK2 | 0.690895 | 4 | 0 | 4 |
| RPGRIP1 | KIR2DL4 | 0.688312 | 5 | 0 | 5 |
| RPGRIP1 | HECW1 | 0.687278 | 5 | 0 | 5 |
| RPGRIP1 | GNG3 | 0.686864 | 4 | 0 | 4 |
| RPGRIP1 | CIITA | 0.684687 | 4 | 0 | 4 |
| RPGRIP1 | GALNT8 | 0.68266 | 4 | 0 | 4 |
| RPGRIP1 | PRLR | 0.678378 | 4 | 0 | 4 |
| RPGRIP1 | RUNDC3A | 0.678144 | 4 | 0 | 3 |
For details and further investigation, click here
