| Full name: histidine rich glycoprotein | Alias Symbol: HRGP|HPRG | ||
| Type: protein-coding gene | Cytoband: 3q27.3 | ||
| Entrez ID: 3273 | HGNC ID: HGNC:5181 | Ensembl Gene: ENSG00000113905 | OMIM ID: 142640 |
| Drug and gene relationship at DGIdb | |||
Expression of HRG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HRG | 3273 | 31835_at | 0.0329 | 0.8759 | |
| GSE20347 | HRG | 3273 | 31835_at | 0.1215 | 0.1446 | |
| GSE23400 | HRG | 3273 | 206226_at | -0.1975 | 0.0004 | |
| GSE26886 | HRG | 3273 | 206226_at | 0.1840 | 0.2193 | |
| GSE29001 | HRG | 3273 | 31835_at | 0.0309 | 0.8107 | |
| GSE38129 | HRG | 3273 | 31835_at | 0.0402 | 0.6181 | |
| GSE45670 | HRG | 3273 | 31835_at | 0.2214 | 0.0011 | |
| GSE53622 | HRG | 3273 | 94433 | 0.4611 | 0.0081 | |
| GSE53624 | HRG | 3273 | 94433 | 1.0341 | 0.0000 | |
| GSE63941 | HRG | 3273 | 31835_at | 0.3042 | 0.0407 | |
| GSE77861 | HRG | 3273 | 206226_at | 0.0048 | 0.9763 | |
| TCGA | HRG | 3273 | RNAseq | 3.3267 | 0.0002 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by HRG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HRG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HRG | 3273 | 24 | 0 | 6 | |
| GSE20123 | HRG | 3273 | 24 | 0 | 6 | |
| GSE43470 | HRG | 3273 | 23 | 0 | 20 | |
| GSE46452 | HRG | 3273 | 19 | 1 | 39 | |
| GSE47630 | HRG | 3273 | 27 | 2 | 11 | |
| GSE54993 | HRG | 3273 | 1 | 19 | 50 | |
| GSE54994 | HRG | 3273 | 40 | 0 | 13 | |
| GSE60625 | HRG | 3273 | 0 | 6 | 5 | |
| GSE74703 | HRG | 3273 | 20 | 0 | 16 | |
| GSE74704 | HRG | 3273 | 16 | 0 | 4 | |
| TCGA | HRG | 3273 | 77 | 0 | 19 |
Total number of gains: 271; Total number of losses: 28; Total Number of normals: 189.
Somatic mutations of HRG:
Generating mutation plots.
Highly correlated genes for HRG:
Showing top 20/630 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HRG | RPGRIP1 | 0.736808 | 4 | 0 | 4 |
| HRG | IFNA17 | 0.732971 | 4 | 0 | 4 |
| HRG | AICDA | 0.727159 | 4 | 0 | 4 |
| HRG | TAOK1 | 0.726902 | 3 | 0 | 3 |
| HRG | KHDRBS2 | 0.720868 | 6 | 0 | 6 |
| HRG | IFNA10 | 0.71468 | 4 | 0 | 4 |
| HRG | SLC17A4 | 0.709028 | 5 | 0 | 5 |
| HRG | OR10H3 | 0.700765 | 5 | 0 | 5 |
| HRG | PRR34 | 0.699368 | 4 | 0 | 4 |
| HRG | ZMAT4 | 0.698132 | 3 | 0 | 3 |
| HRG | CYP2D6 | 0.696011 | 4 | 0 | 4 |
| HRG | TRPM3 | 0.694172 | 5 | 0 | 4 |
| HRG | LGALS14 | 0.690048 | 4 | 0 | 4 |
| HRG | PRODH2 | 0.689681 | 4 | 0 | 4 |
| HRG | RUNX2 | 0.688035 | 4 | 0 | 4 |
| HRG | HAUS5 | 0.687018 | 3 | 0 | 3 |
| HRG | MYEF2 | 0.685712 | 3 | 0 | 3 |
| HRG | DPF3 | 0.684826 | 4 | 0 | 4 |
| HRG | FOLH1 | 0.682334 | 5 | 0 | 4 |
| HRG | CACNB1 | 0.682053 | 4 | 0 | 4 |
For details and further investigation, click here
