| Full name: importin 13 | Alias Symbol: IMP13|KIAA0724|RANBP13 | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 9670 | HGNC ID: HGNC:16853 | Ensembl Gene: ENSG00000117408 | OMIM ID: 610411 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of IPO13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IPO13 | 9670 | 203546_at | 0.3106 | 0.2838 | |
| GSE20347 | IPO13 | 9670 | 203546_at | -0.0017 | 0.9916 | |
| GSE23400 | IPO13 | 9670 | 203546_at | -0.0500 | 0.3680 | |
| GSE26886 | IPO13 | 9670 | 203546_at | 0.1892 | 0.2594 | |
| GSE29001 | IPO13 | 9670 | 203546_at | -0.1184 | 0.6610 | |
| GSE38129 | IPO13 | 9670 | 203546_at | -0.0061 | 0.9615 | |
| GSE45670 | IPO13 | 9670 | 203546_at | 0.2899 | 0.0245 | |
| GSE53622 | IPO13 | 9670 | 6608 | 0.0352 | 0.5461 | |
| GSE53624 | IPO13 | 9670 | 6608 | 0.2198 | 0.0001 | |
| GSE63941 | IPO13 | 9670 | 203546_at | 0.4192 | 0.2168 | |
| GSE77861 | IPO13 | 9670 | 203546_at | -0.1288 | 0.6523 | |
| GSE97050 | IPO13 | 9670 | A_23_P115036 | 0.0576 | 0.7743 | |
| SRP007169 | IPO13 | 9670 | RNAseq | 1.4082 | 0.0048 | |
| SRP008496 | IPO13 | 9670 | RNAseq | 0.9543 | 0.0053 | |
| SRP064894 | IPO13 | 9670 | RNAseq | 0.7515 | 0.0000 | |
| SRP133303 | IPO13 | 9670 | RNAseq | 0.4220 | 0.0025 | |
| SRP159526 | IPO13 | 9670 | RNAseq | 0.4700 | 0.1336 | |
| SRP193095 | IPO13 | 9670 | RNAseq | 0.4967 | 0.0000 | |
| SRP219564 | IPO13 | 9670 | RNAseq | 0.6131 | 0.1374 | |
| TCGA | IPO13 | 9670 | RNAseq | -0.0125 | 0.8026 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IPO13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IPO13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IPO13 | 9670 | 4 | 3 | 23 | |
| GSE20123 | IPO13 | 9670 | 4 | 2 | 24 | |
| GSE43470 | IPO13 | 9670 | 7 | 2 | 34 | |
| GSE46452 | IPO13 | 9670 | 2 | 1 | 56 | |
| GSE47630 | IPO13 | 9670 | 9 | 3 | 28 | |
| GSE54993 | IPO13 | 9670 | 0 | 2 | 68 | |
| GSE54994 | IPO13 | 9670 | 14 | 2 | 37 | |
| GSE60625 | IPO13 | 9670 | 0 | 0 | 11 | |
| GSE74703 | IPO13 | 9670 | 6 | 1 | 29 | |
| GSE74704 | IPO13 | 9670 | 2 | 0 | 18 | |
| TCGA | IPO13 | 9670 | 14 | 16 | 66 |
Total number of gains: 62; Total number of losses: 32; Total Number of normals: 394.
Somatic mutations of IPO13:
Generating mutation plots.
Highly correlated genes for IPO13:
Showing top 20/268 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IPO13 | CC2D1B | 0.829589 | 4 | 0 | 4 |
| IPO13 | ZNF524 | 0.813141 | 3 | 0 | 3 |
| IPO13 | PPP1R13B | 0.811476 | 3 | 0 | 3 |
| IPO13 | GPC2 | 0.790484 | 3 | 0 | 3 |
| IPO13 | SMARCB1 | 0.763538 | 3 | 0 | 3 |
| IPO13 | ZNF777 | 0.757187 | 3 | 0 | 3 |
| IPO13 | SPINT3 | 0.75231 | 3 | 0 | 3 |
| IPO13 | MAPK15 | 0.749347 | 3 | 0 | 3 |
| IPO13 | CPNE6 | 0.734449 | 3 | 0 | 3 |
| IPO13 | JSRP1 | 0.730849 | 3 | 0 | 3 |
| IPO13 | NOBOX | 0.728532 | 3 | 0 | 3 |
| IPO13 | LRFN4 | 0.728095 | 4 | 0 | 3 |
| IPO13 | BMP8B | 0.719491 | 3 | 0 | 3 |
| IPO13 | LMAN1L | 0.712482 | 4 | 0 | 3 |
| IPO13 | GRIPAP1 | 0.712481 | 3 | 0 | 3 |
| IPO13 | TULP1 | 0.703637 | 3 | 0 | 3 |
| IPO13 | CDK16 | 0.703412 | 4 | 0 | 3 |
| IPO13 | LRCH4 | 0.701276 | 4 | 0 | 4 |
| IPO13 | LHFPL5 | 0.698367 | 3 | 0 | 3 |
| IPO13 | TNXB | 0.694797 | 3 | 0 | 3 |
For details and further investigation, click here
