| Full name: CASP2 and RIPK1 domain containing adaptor with death domain | Alias Symbol: RAIDD | ||
| Type: protein-coding gene | Cytoband: 12q22 | ||
| Entrez ID: 8738 | HGNC ID: HGNC:2340 | Ensembl Gene: ENSG00000169372 | OMIM ID: 603454 |
| Drug and gene relationship at DGIdb | |||
Expression of CRADD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRADD | 8738 | 209833_at | -0.7431 | 0.2643 | |
| GSE20347 | CRADD | 8738 | 209833_at | -0.3468 | 0.0025 | |
| GSE23400 | CRADD | 8738 | 209833_at | -0.2944 | 0.0000 | |
| GSE26886 | CRADD | 8738 | 209833_at | -0.6781 | 0.0001 | |
| GSE29001 | CRADD | 8738 | 209833_at | -0.3519 | 0.0533 | |
| GSE38129 | CRADD | 8738 | 209833_at | -0.3722 | 0.0024 | |
| GSE45670 | CRADD | 8738 | 209833_at | -0.5570 | 0.0001 | |
| GSE53622 | CRADD | 8738 | 26659 | -0.6767 | 0.0000 | |
| GSE53624 | CRADD | 8738 | 26659 | -0.5509 | 0.0000 | |
| GSE63941 | CRADD | 8738 | 209833_at | -0.5056 | 0.0773 | |
| GSE77861 | CRADD | 8738 | 209833_at | -0.5608 | 0.0296 | |
| GSE97050 | CRADD | 8738 | A_32_P29806 | -0.1227 | 0.6357 | |
| SRP007169 | CRADD | 8738 | RNAseq | -1.5867 | 0.0030 | |
| SRP008496 | CRADD | 8738 | RNAseq | -1.4059 | 0.0000 | |
| SRP064894 | CRADD | 8738 | RNAseq | -0.7236 | 0.0001 | |
| SRP133303 | CRADD | 8738 | RNAseq | -0.2985 | 0.3231 | |
| SRP159526 | CRADD | 8738 | RNAseq | -0.6779 | 0.1379 | |
| SRP193095 | CRADD | 8738 | RNAseq | -0.6641 | 0.0000 | |
| SRP219564 | CRADD | 8738 | RNAseq | -0.9319 | 0.0039 | |
| TCGA | CRADD | 8738 | RNAseq | -0.2777 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CRADD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRADD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRADD | 8738 | 3 | 2 | 25 | |
| GSE20123 | CRADD | 8738 | 3 | 2 | 25 | |
| GSE43470 | CRADD | 8738 | 3 | 0 | 40 | |
| GSE46452 | CRADD | 8738 | 9 | 1 | 49 | |
| GSE47630 | CRADD | 8738 | 10 | 1 | 29 | |
| GSE54993 | CRADD | 8738 | 0 | 5 | 65 | |
| GSE54994 | CRADD | 8738 | 5 | 2 | 46 | |
| GSE60625 | CRADD | 8738 | 0 | 0 | 11 | |
| GSE74703 | CRADD | 8738 | 3 | 0 | 33 | |
| GSE74704 | CRADD | 8738 | 1 | 2 | 17 | |
| TCGA | CRADD | 8738 | 17 | 11 | 68 |
Total number of gains: 54; Total number of losses: 26; Total Number of normals: 408.
Somatic mutations of CRADD:
Generating mutation plots.
Highly correlated genes for CRADD:
Showing top 20/1432 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRADD | ZNF784 | 0.774477 | 3 | 0 | 3 |
| CRADD | SNORA68 | 0.763027 | 4 | 0 | 4 |
| CRADD | ARFGAP2 | 0.737367 | 3 | 0 | 3 |
| CRADD | RNASEK | 0.73643 | 3 | 0 | 3 |
| CRADD | BNIP1 | 0.733191 | 3 | 0 | 3 |
| CRADD | FUNDC2 | 0.729461 | 3 | 0 | 3 |
| CRADD | ANKRD13A | 0.725064 | 6 | 0 | 6 |
| CRADD | DCTD | 0.724982 | 5 | 0 | 5 |
| CRADD | MKRN1 | 0.722196 | 4 | 0 | 3 |
| CRADD | SMURF1 | 0.721571 | 3 | 0 | 3 |
| CRADD | FGD4 | 0.719935 | 4 | 0 | 4 |
| CRADD | CCDC12 | 0.716146 | 5 | 0 | 5 |
| CRADD | TMEM167B | 0.714558 | 5 | 0 | 4 |
| CRADD | VSIG10L | 0.712278 | 4 | 0 | 4 |
| CRADD | GPR108 | 0.711612 | 3 | 0 | 3 |
| CRADD | HOOK3 | 0.711263 | 3 | 0 | 3 |
| CRADD | TMEM19 | 0.709757 | 5 | 0 | 4 |
| CRADD | CYP4V2 | 0.707832 | 4 | 0 | 4 |
| CRADD | ABHD14B | 0.707479 | 6 | 0 | 5 |
| CRADD | ALKBH7 | 0.703746 | 7 | 0 | 6 |
For details and further investigation, click here
