| Full name: coiled-coil domain containing 12 | Alias Symbol: MGC23918 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 151903 | HGNC ID: HGNC:28332 | Ensembl Gene: ENSG00000160799 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCDC12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC12 | 151903 | 226011_at | -0.3184 | 0.4565 | |
| GSE26886 | CCDC12 | 151903 | 226011_at | -0.2360 | 0.2025 | |
| GSE45670 | CCDC12 | 151903 | 226011_at | -0.3199 | 0.0072 | |
| GSE53622 | CCDC12 | 151903 | 6389 | -1.0287 | 0.0000 | |
| GSE53624 | CCDC12 | 151903 | 6389 | -0.9250 | 0.0000 | |
| GSE63941 | CCDC12 | 151903 | 226011_at | 0.0724 | 0.7520 | |
| GSE77861 | CCDC12 | 151903 | 226011_at | -0.4905 | 0.0060 | |
| GSE97050 | CCDC12 | 151903 | A_23_P372334 | -0.1869 | 0.4555 | |
| SRP007169 | CCDC12 | 151903 | RNAseq | -0.9730 | 0.0121 | |
| SRP008496 | CCDC12 | 151903 | RNAseq | -1.4830 | 0.0000 | |
| SRP064894 | CCDC12 | 151903 | RNAseq | -0.3345 | 0.2903 | |
| SRP133303 | CCDC12 | 151903 | RNAseq | -1.0102 | 0.0000 | |
| SRP159526 | CCDC12 | 151903 | RNAseq | -1.0709 | 0.0000 | |
| SRP193095 | CCDC12 | 151903 | RNAseq | -1.0463 | 0.0000 | |
| SRP219564 | CCDC12 | 151903 | RNAseq | -0.5239 | 0.1707 | |
| TCGA | CCDC12 | 151903 | RNAseq | -0.0744 | 0.2228 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CCDC12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC12 | 151903 | 0 | 18 | 12 | |
| GSE20123 | CCDC12 | 151903 | 0 | 19 | 11 | |
| GSE43470 | CCDC12 | 151903 | 0 | 19 | 24 | |
| GSE46452 | CCDC12 | 151903 | 2 | 17 | 40 | |
| GSE47630 | CCDC12 | 151903 | 2 | 23 | 15 | |
| GSE54993 | CCDC12 | 151903 | 7 | 2 | 61 | |
| GSE54994 | CCDC12 | 151903 | 0 | 36 | 17 | |
| GSE60625 | CCDC12 | 151903 | 5 | 0 | 6 | |
| GSE74703 | CCDC12 | 151903 | 0 | 15 | 21 | |
| GSE74704 | CCDC12 | 151903 | 0 | 12 | 8 | |
| TCGA | CCDC12 | 151903 | 1 | 75 | 20 |
Total number of gains: 17; Total number of losses: 236; Total Number of normals: 235.
Somatic mutations of CCDC12:
Generating mutation plots.
Highly correlated genes for CCDC12:
Showing top 20/1444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC12 | EHD3 | 0.780847 | 5 | 0 | 5 |
| CCDC12 | POLR2L | 0.768872 | 3 | 0 | 3 |
| CCDC12 | LRRFIP2 | 0.764931 | 6 | 0 | 6 |
| CCDC12 | VSIG10L | 0.75486 | 4 | 0 | 4 |
| CCDC12 | ANXA9 | 0.753411 | 5 | 0 | 5 |
| CCDC12 | CPPED1 | 0.752897 | 5 | 0 | 5 |
| CCDC12 | ULK3 | 0.751226 | 5 | 0 | 5 |
| CCDC12 | MGLL | 0.750129 | 5 | 0 | 5 |
| CCDC12 | EMC3 | 0.747594 | 4 | 0 | 4 |
| CCDC12 | BARX2 | 0.746731 | 6 | 0 | 6 |
| CCDC12 | BLOC1S1 | 0.7458 | 6 | 0 | 6 |
| CCDC12 | PLEKHM1 | 0.745088 | 5 | 0 | 5 |
| CCDC12 | NDST1 | 0.741636 | 4 | 0 | 4 |
| CCDC12 | GMDS | 0.741334 | 5 | 0 | 5 |
| CCDC12 | SH3GLB1 | 0.741083 | 5 | 0 | 5 |
| CCDC12 | GPR108 | 0.740162 | 3 | 0 | 3 |
| CCDC12 | AK3 | 0.738839 | 4 | 0 | 4 |
| CCDC12 | FNDC4 | 0.737072 | 4 | 0 | 4 |
| CCDC12 | CASC3 | 0.736541 | 3 | 0 | 3 |
| CCDC12 | CA13 | 0.736209 | 3 | 0 | 3 |
For details and further investigation, click here
