| Full name: cell adhesion molecule 3 | Alias Symbol: BIgR|FLJ10698|TSLL1|NECL1|SynCAM3|Necl-1 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 57863 | HGNC ID: HGNC:17601 | Ensembl Gene: ENSG00000162706 | OMIM ID: 609743 |
| Drug and gene relationship at DGIdb | |||
Expression of CADM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CADM3 | 57863 | 211677_x_at | -0.3015 | 0.2866 | |
| GSE20347 | CADM3 | 57863 | 211677_x_at | -0.0489 | 0.6622 | |
| GSE23400 | CADM3 | 57863 | 211677_x_at | -0.3529 | 0.0000 | |
| GSE26886 | CADM3 | 57863 | 211677_x_at | 0.1334 | 0.2948 | |
| GSE29001 | CADM3 | 57863 | 211677_x_at | -0.2781 | 0.1045 | |
| GSE38129 | CADM3 | 57863 | 211677_x_at | -0.4405 | 0.0001 | |
| GSE45670 | CADM3 | 57863 | 211677_x_at | -0.1434 | 0.1281 | |
| GSE53622 | CADM3 | 57863 | 55845 | -1.9315 | 0.0000 | |
| GSE53624 | CADM3 | 57863 | 55845 | -2.1859 | 0.0000 | |
| GSE63941 | CADM3 | 57863 | 211677_x_at | 0.0115 | 0.9522 | |
| GSE77861 | CADM3 | 57863 | 211677_x_at | -0.2355 | 0.1039 | |
| GSE97050 | CADM3 | 57863 | A_33_P3421923 | -0.6729 | 0.1057 | |
| SRP064894 | CADM3 | 57863 | RNAseq | -1.1668 | 0.0309 | |
| SRP133303 | CADM3 | 57863 | RNAseq | -2.8386 | 0.0000 | |
| SRP159526 | CADM3 | 57863 | RNAseq | -2.0356 | 0.0102 | |
| SRP219564 | CADM3 | 57863 | RNAseq | 0.2587 | 0.7678 | |
| TCGA | CADM3 | 57863 | RNAseq | -1.7285 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CADM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CADM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CADM3 | 57863 | 10 | 0 | 20 | |
| GSE20123 | CADM3 | 57863 | 10 | 0 | 20 | |
| GSE43470 | CADM3 | 57863 | 7 | 2 | 34 | |
| GSE46452 | CADM3 | 57863 | 2 | 1 | 56 | |
| GSE47630 | CADM3 | 57863 | 14 | 0 | 26 | |
| GSE54993 | CADM3 | 57863 | 0 | 5 | 65 | |
| GSE54994 | CADM3 | 57863 | 16 | 0 | 37 | |
| GSE60625 | CADM3 | 57863 | 0 | 0 | 11 | |
| GSE74703 | CADM3 | 57863 | 7 | 2 | 27 | |
| GSE74704 | CADM3 | 57863 | 4 | 0 | 16 | |
| TCGA | CADM3 | 57863 | 42 | 3 | 51 |
Total number of gains: 112; Total number of losses: 13; Total Number of normals: 363.
Somatic mutations of CADM3:
Generating mutation plots.
Highly correlated genes for CADM3:
Showing top 20/1479 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CADM3 | TNFSF12 | 0.799573 | 3 | 0 | 3 |
| CADM3 | XKR4 | 0.79762 | 4 | 0 | 4 |
| CADM3 | ITPR1 | 0.793034 | 4 | 0 | 4 |
| CADM3 | XRRA1 | 0.782865 | 3 | 0 | 3 |
| CADM3 | RAB9B | 0.78076 | 4 | 0 | 4 |
| CADM3 | CCL14 | 0.780638 | 3 | 0 | 3 |
| CADM3 | CLEC3B | 0.779285 | 4 | 0 | 3 |
| CADM3 | TCF21 | 0.775613 | 4 | 0 | 4 |
| CADM3 | RBPMS2 | 0.77497 | 4 | 0 | 4 |
| CADM3 | PLN | 0.773685 | 4 | 0 | 4 |
| CADM3 | SMYD1 | 0.771783 | 4 | 0 | 3 |
| CADM3 | MAMDC2 | 0.7694 | 4 | 0 | 4 |
| CADM3 | IL6ST | 0.766944 | 4 | 0 | 4 |
| CADM3 | FBLN1 | 0.762787 | 4 | 0 | 4 |
| CADM3 | CYP2U1 | 0.757659 | 4 | 0 | 4 |
| CADM3 | LRFN5 | 0.755941 | 5 | 0 | 5 |
| CADM3 | NEGR1 | 0.755407 | 4 | 0 | 4 |
| CADM3 | ZNF582 | 0.754621 | 3 | 0 | 3 |
| CADM3 | AKAP12 | 0.753136 | 4 | 0 | 4 |
| CADM3 | PDE5A | 0.7509 | 5 | 0 | 5 |
For details and further investigation, click here
