| Full name: metallothionein 4 | Alias Symbol: MTIV | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 84560 | HGNC ID: HGNC:18705 | Ensembl Gene: ENSG00000102891 | OMIM ID: 606206 |
| Drug and gene relationship at DGIdb | |||
Expression of MT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MT4 | 84560 | 217395_at | -0.3928 | 0.2830 | |
| GSE20347 | MT4 | 84560 | 217395_at | -0.0997 | 0.3522 | |
| GSE23400 | MT4 | 84560 | 217395_at | -0.0997 | 0.0271 | |
| GSE26886 | MT4 | 84560 | 217395_at | -0.3724 | 0.0010 | |
| GSE29001 | MT4 | 84560 | 217395_at | -0.2194 | 0.1159 | |
| GSE38129 | MT4 | 84560 | 217395_at | -0.1749 | 0.0952 | |
| GSE45670 | MT4 | 84560 | 217395_at | -0.1418 | 0.3719 | |
| GSE63941 | MT4 | 84560 | 217395_at | -0.2293 | 0.1768 | |
| GSE77861 | MT4 | 84560 | 217395_at | -0.3373 | 0.0199 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MT4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MT4 | 84560 | 5 | 0 | 25 | |
| GSE20123 | MT4 | 84560 | 5 | 1 | 24 | |
| GSE43470 | MT4 | 84560 | 2 | 7 | 34 | |
| GSE46452 | MT4 | 84560 | 38 | 1 | 20 | |
| GSE47630 | MT4 | 84560 | 10 | 8 | 22 | |
| GSE54993 | MT4 | 84560 | 2 | 4 | 64 | |
| GSE54994 | MT4 | 84560 | 7 | 10 | 36 | |
| GSE60625 | MT4 | 84560 | 4 | 0 | 7 | |
| GSE74703 | MT4 | 84560 | 2 | 4 | 30 | |
| GSE74704 | MT4 | 84560 | 4 | 0 | 16 | |
| TCGA | MT4 | 84560 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 47; Total Number of normals: 337.
Somatic mutations of MT4:
Generating mutation plots.
Highly correlated genes for MT4:
Showing top 20/922 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MT4 | ACADM | 0.765896 | 3 | 0 | 3 |
| MT4 | MVK | 0.715162 | 7 | 0 | 7 |
| MT4 | SYNGR1 | 0.707776 | 4 | 0 | 4 |
| MT4 | MRGPRG-AS1 | 0.700137 | 4 | 0 | 4 |
| MT4 | SNX3 | 0.696056 | 3 | 0 | 3 |
| MT4 | TRIM61 | 0.694487 | 3 | 0 | 3 |
| MT4 | CRISP1 | 0.693861 | 4 | 0 | 4 |
| MT4 | OR2L2 | 0.692246 | 3 | 0 | 3 |
| MT4 | SAR1B | 0.690285 | 3 | 0 | 3 |
| MT4 | CPPED1 | 0.684888 | 3 | 0 | 3 |
| MT4 | MAPK11 | 0.682767 | 3 | 0 | 3 |
| MT4 | ARRDC3 | 0.682373 | 3 | 0 | 3 |
| MT4 | PHYHD1 | 0.680636 | 3 | 0 | 3 |
| MT4 | C1orf68 | 0.678932 | 3 | 0 | 3 |
| MT4 | DOK1 | 0.6771 | 3 | 0 | 3 |
| MT4 | MYL1 | 0.676646 | 5 | 0 | 5 |
| MT4 | KLK5 | 0.675832 | 4 | 0 | 4 |
| MT4 | ODF4 | 0.674422 | 3 | 0 | 3 |
| MT4 | VSIG10L | 0.670034 | 3 | 0 | 3 |
| MT4 | CACFD1 | 0.669735 | 7 | 0 | 7 |
For details and further investigation, click here
