| Full name: cysteine rich secretory protein LCCL domain containing 2 | Alias Symbol: DKFZP434B044|LGL1 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 83716 | HGNC ID: HGNC:25248 | Ensembl Gene: ENSG00000103196 | OMIM ID: 612434 |
| Drug and gene relationship at DGIdb | |||
Expression of CRISPLD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRISPLD2 | 83716 | 221541_at | -0.8397 | 0.3512 | |
| GSE20347 | CRISPLD2 | 83716 | 221541_at | 0.4248 | 0.1354 | |
| GSE23400 | CRISPLD2 | 83716 | 221541_at | 0.0386 | 0.8368 | |
| GSE26886 | CRISPLD2 | 83716 | 221541_at | 1.5719 | 0.0004 | |
| GSE29001 | CRISPLD2 | 83716 | 221541_at | 0.2282 | 0.6071 | |
| GSE38129 | CRISPLD2 | 83716 | 221541_at | -0.0307 | 0.9554 | |
| GSE45670 | CRISPLD2 | 83716 | 221541_at | -1.8139 | 0.0002 | |
| GSE53622 | CRISPLD2 | 83716 | 3519 | -0.0340 | 0.8529 | |
| GSE53624 | CRISPLD2 | 83716 | 3519 | 0.1603 | 0.3228 | |
| GSE63941 | CRISPLD2 | 83716 | 221541_at | -3.4284 | 0.0007 | |
| GSE77861 | CRISPLD2 | 83716 | 221541_at | 0.8295 | 0.0329 | |
| GSE97050 | CRISPLD2 | 83716 | A_23_P106602 | 0.2051 | 0.3408 | |
| SRP007169 | CRISPLD2 | 83716 | RNAseq | 2.7165 | 0.0000 | |
| SRP008496 | CRISPLD2 | 83716 | RNAseq | 3.0701 | 0.0000 | |
| SRP064894 | CRISPLD2 | 83716 | RNAseq | 0.0669 | 0.8825 | |
| SRP133303 | CRISPLD2 | 83716 | RNAseq | 0.3405 | 0.3134 | |
| SRP159526 | CRISPLD2 | 83716 | RNAseq | -0.3460 | 0.2018 | |
| SRP193095 | CRISPLD2 | 83716 | RNAseq | 1.2546 | 0.0003 | |
| SRP219564 | CRISPLD2 | 83716 | RNAseq | 0.0791 | 0.9267 | |
| TCGA | CRISPLD2 | 83716 | RNAseq | -0.5903 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 2.
Survival by CRISPLD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRISPLD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRISPLD2 | 83716 | 4 | 5 | 21 | |
| GSE20123 | CRISPLD2 | 83716 | 4 | 5 | 21 | |
| GSE43470 | CRISPLD2 | 83716 | 2 | 10 | 31 | |
| GSE46452 | CRISPLD2 | 83716 | 37 | 2 | 20 | |
| GSE47630 | CRISPLD2 | 83716 | 11 | 9 | 20 | |
| GSE54993 | CRISPLD2 | 83716 | 3 | 4 | 63 | |
| GSE54994 | CRISPLD2 | 83716 | 8 | 10 | 35 | |
| GSE60625 | CRISPLD2 | 83716 | 4 | 0 | 7 | |
| GSE74703 | CRISPLD2 | 83716 | 2 | 7 | 27 | |
| GSE74704 | CRISPLD2 | 83716 | 3 | 3 | 14 | |
| TCGA | CRISPLD2 | 83716 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 71; Total Number of normals: 313.
Somatic mutations of CRISPLD2:
Generating mutation plots.
Highly correlated genes for CRISPLD2:
Showing top 20/1227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRISPLD2 | C11orf96 | 0.835342 | 5 | 0 | 5 |
| CRISPLD2 | JMY | 0.81166 | 3 | 0 | 3 |
| CRISPLD2 | FBN1 | 0.805985 | 10 | 0 | 10 |
| CRISPLD2 | FILIP1L | 0.786328 | 13 | 0 | 13 |
| CRISPLD2 | PMP22 | 0.772091 | 13 | 0 | 12 |
| CRISPLD2 | PTGFRN | 0.769558 | 3 | 0 | 3 |
| CRISPLD2 | ANXA6 | 0.767523 | 11 | 0 | 10 |
| CRISPLD2 | PLBD2 | 0.766565 | 3 | 0 | 3 |
| CRISPLD2 | CPT1C | 0.757041 | 3 | 0 | 3 |
| CRISPLD2 | HNRNPUL2 | 0.751741 | 3 | 0 | 3 |
| CRISPLD2 | CEP78 | 0.749782 | 3 | 0 | 3 |
| CRISPLD2 | DEGS1 | 0.749314 | 4 | 0 | 4 |
| CRISPLD2 | CNRIP1 | 0.74329 | 9 | 0 | 8 |
| CRISPLD2 | TK2 | 0.736788 | 4 | 0 | 4 |
| CRISPLD2 | ZCCHC24 | 0.734335 | 12 | 0 | 11 |
| CRISPLD2 | STOML1 | 0.733186 | 3 | 0 | 3 |
| CRISPLD2 | PRKG1 | 0.731031 | 9 | 0 | 8 |
| CRISPLD2 | COL15A1 | 0.72908 | 12 | 0 | 12 |
| CRISPLD2 | IFITM1 | 0.727872 | 4 | 0 | 4 |
| CRISPLD2 | CLMP | 0.727353 | 7 | 0 | 6 |
For details and further investigation, click here
