| Full name: interferon induced transmembrane protein 1 | Alias Symbol: 9-27|CD225|DSPA2a | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 8519 | HGNC ID: HGNC:5412 | Ensembl Gene: ENSG00000185885 | OMIM ID: 604456 |
| Drug and gene relationship at DGIdb | |||
Expression of IFITM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFITM1 | 8519 | 214022_s_at | 0.2652 | 0.6496 | |
| GSE20347 | IFITM1 | 8519 | 214022_s_at | 1.2424 | 0.0000 | |
| GSE23400 | IFITM1 | 8519 | 214022_s_at | 0.9781 | 0.0000 | |
| GSE26886 | IFITM1 | 8519 | 214022_s_at | 2.3079 | 0.0001 | |
| GSE29001 | IFITM1 | 8519 | 214022_s_at | 1.5384 | 0.0006 | |
| GSE38129 | IFITM1 | 8519 | 214022_s_at | 0.7662 | 0.0038 | |
| GSE45670 | IFITM1 | 8519 | 214022_s_at | 0.9294 | 0.0179 | |
| GSE63941 | IFITM1 | 8519 | 214022_s_at | -0.0319 | 0.9829 | |
| GSE77861 | IFITM1 | 8519 | 214022_s_at | 1.3133 | 0.0066 | |
| GSE97050 | IFITM1 | 8519 | A_33_P3423941 | 1.1803 | 0.0834 | |
| SRP007169 | IFITM1 | 8519 | RNAseq | 1.9360 | 0.0003 | |
| SRP008496 | IFITM1 | 8519 | RNAseq | 1.8610 | 0.0000 | |
| SRP064894 | IFITM1 | 8519 | RNAseq | 1.5241 | 0.0000 | |
| SRP133303 | IFITM1 | 8519 | RNAseq | 0.5609 | 0.0448 | |
| SRP159526 | IFITM1 | 8519 | RNAseq | 0.0158 | 0.9706 | |
| SRP193095 | IFITM1 | 8519 | RNAseq | 1.8106 | 0.0000 | |
| SRP219564 | IFITM1 | 8519 | RNAseq | 0.9740 | 0.0457 | |
| TCGA | IFITM1 | 8519 | RNAseq | 0.4616 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by IFITM1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IFITM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFITM1 | 8519 | 1 | 11 | 18 | |
| GSE20123 | IFITM1 | 8519 | 1 | 12 | 17 | |
| GSE43470 | IFITM1 | 8519 | 1 | 10 | 32 | |
| GSE46452 | IFITM1 | 8519 | 7 | 8 | 44 | |
| GSE47630 | IFITM1 | 8519 | 4 | 12 | 24 | |
| GSE54993 | IFITM1 | 8519 | 3 | 2 | 65 | |
| GSE54994 | IFITM1 | 8519 | 1 | 12 | 40 | |
| GSE60625 | IFITM1 | 8519 | 0 | 0 | 11 | |
| GSE74703 | IFITM1 | 8519 | 1 | 8 | 27 | |
| GSE74704 | IFITM1 | 8519 | 0 | 8 | 12 | |
| TCGA | IFITM1 | 8519 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of IFITM1:
Generating mutation plots.
Highly correlated genes for IFITM1:
Showing top 20/1624 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFITM1 | IFITM3 | 0.884912 | 11 | 0 | 11 |
| IFITM1 | IFITM2 | 0.842155 | 11 | 0 | 11 |
| IFITM1 | IFI35 | 0.807536 | 10 | 0 | 10 |
| IFITM1 | ARPC1B | 0.7871 | 8 | 0 | 8 |
| IFITM1 | IFI44L | 0.775964 | 10 | 0 | 9 |
| IFITM1 | PPP1R35 | 0.774283 | 3 | 0 | 3 |
| IFITM1 | BRI3 | 0.773591 | 3 | 0 | 3 |
| IFITM1 | IFIT3 | 0.760887 | 9 | 0 | 9 |
| IFITM1 | XPR1 | 0.759493 | 4 | 0 | 4 |
| IFITM1 | PARP12 | 0.759474 | 9 | 0 | 8 |
| IFITM1 | IFI6 | 0.756417 | 11 | 0 | 10 |
| IFITM1 | HERC5 | 0.756183 | 10 | 0 | 10 |
| IFITM1 | CD276 | 0.754181 | 3 | 0 | 3 |
| IFITM1 | RAVER1 | 0.752646 | 3 | 0 | 3 |
| IFITM1 | SLC30A7 | 0.750434 | 4 | 0 | 4 |
| IFITM1 | RASA3 | 0.746616 | 3 | 0 | 3 |
| IFITM1 | IFI44 | 0.745619 | 10 | 0 | 9 |
| IFITM1 | IFIT1 | 0.740317 | 9 | 0 | 9 |
| IFITM1 | FBLIM1 | 0.739806 | 4 | 0 | 4 |
| IFITM1 | C12orf75 | 0.739395 | 4 | 0 | 4 |
For details and further investigation, click here
