FILIP1L

 

Full name: filamin A interacting protein 1 like Alias Symbol: DOC-1|GIP130
Type: protein-coding gene Cytoband: 3q12.1
Entrez ID: 11259 HGNC ID: HGNC:24589 Ensembl Gene: ENSG00000168386 OMIM ID: 612993
Drug and gene relationship at DGIdb

 

Expression of FILIP1L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FILIP1L 11259 204135_at -1.0056 0.2675
GSE20347 FILIP1L 11259 204135_at 0.4083 0.2838
GSE23400 FILIP1L 11259 204135_at 0.0727 0.7562
GSE26886 FILIP1L 11259 204135_at 1.0179 0.0737
GSE29001 FILIP1L 11259 204135_at 0.0636 0.9059
GSE38129 FILIP1L 11259 204135_at -0.0746 0.8950
GSE45670 FILIP1L 11259 204135_at -1.4390 0.0045
GSE53622 FILIP1L 11259 112847 -0.1959 0.1889
GSE53624 FILIP1L 11259 112847 0.0508 0.6873
GSE63941 FILIP1L 11259 204135_at -6.2512 0.0001
GSE77861 FILIP1L 11259 204135_at 0.7815 0.0703
GSE97050 FILIP1L 11259 A_23_P252052 0.0822 0.8602
SRP007169 FILIP1L 11259 RNAseq 2.5999 0.0000
SRP008496 FILIP1L 11259 RNAseq 2.6820 0.0000
SRP064894 FILIP1L 11259 RNAseq -0.1658 0.6475
SRP133303 FILIP1L 11259 RNAseq 0.5332 0.1547
SRP159526 FILIP1L 11259 RNAseq -0.3551 0.5438
SRP193095 FILIP1L 11259 RNAseq 1.2689 0.0000
SRP219564 FILIP1L 11259 RNAseq -0.7515 0.4634
TCGA FILIP1L 11259 RNAseq -0.6276 0.0000

Upregulated datasets: 3; Downregulated datasets: 2.  


 

Survival by FILIP1L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FILIP1L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FILIP1L 11259 18 1 11
GSE20123 FILIP1L 11259 17 1 12
GSE43470 FILIP1L 11259 19 1 23
GSE46452 FILIP1L 11259 12 6 41
GSE47630 FILIP1L 11259 16 6 18
GSE54993 FILIP1L 11259 2 5 63
GSE54994 FILIP1L 11259 27 5 21
GSE60625 FILIP1L 11259 0 6 5
GSE74703 FILIP1L 11259 15 1 20
GSE74704 FILIP1L 11259 14 1 5
TCGA FILIP1L 11259 50 9 37

Total number of gains: 190; Total number of losses: 42; Total Number of normals: 256.  


 

Somatic mutations of FILIP1L:

 

Generating mutation plots.

 

Highly correlated genes for FILIP1L:

 

Showing top 20/1128 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FILIP1LFIBIN0.833516505
FILIP1LCYP4V20.825309303
FILIP1LZEB10.823128303
FILIP1LLAMA40.80490812012
FILIP1LFERMT20.80442913013
FILIP1LC11orf960.803403505
FILIP1LCALD10.7958213013
FILIP1LDDR20.78749812012
FILIP1LCRISPLD20.78632813013
FILIP1LTMEM470.77756113013
FILIP1LPMP220.77683713012
FILIP1LTGFB1I10.7736612012
FILIP1LPDLIM30.77197413012
FILIP1LFBN10.77072711011
FILIP1LRHOJ0.768829404
FILIP1LCNRIP10.768446909
FILIP1LACTA20.76705113013
FILIP1LDCN0.76609912012
FILIP1LITGA10.76592112011
FILIP1LCOL15A10.76371713013

For details and further investigation, click here