| Full name: filamin A interacting protein 1 like | Alias Symbol: DOC-1|GIP130 | ||
| Type: protein-coding gene | Cytoband: 3q12.1 | ||
| Entrez ID: 11259 | HGNC ID: HGNC:24589 | Ensembl Gene: ENSG00000168386 | OMIM ID: 612993 |
| Drug and gene relationship at DGIdb | |||
Expression of FILIP1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FILIP1L | 11259 | 204135_at | -1.0056 | 0.2675 | |
| GSE20347 | FILIP1L | 11259 | 204135_at | 0.4083 | 0.2838 | |
| GSE23400 | FILIP1L | 11259 | 204135_at | 0.0727 | 0.7562 | |
| GSE26886 | FILIP1L | 11259 | 204135_at | 1.0179 | 0.0737 | |
| GSE29001 | FILIP1L | 11259 | 204135_at | 0.0636 | 0.9059 | |
| GSE38129 | FILIP1L | 11259 | 204135_at | -0.0746 | 0.8950 | |
| GSE45670 | FILIP1L | 11259 | 204135_at | -1.4390 | 0.0045 | |
| GSE53622 | FILIP1L | 11259 | 112847 | -0.1959 | 0.1889 | |
| GSE53624 | FILIP1L | 11259 | 112847 | 0.0508 | 0.6873 | |
| GSE63941 | FILIP1L | 11259 | 204135_at | -6.2512 | 0.0001 | |
| GSE77861 | FILIP1L | 11259 | 204135_at | 0.7815 | 0.0703 | |
| GSE97050 | FILIP1L | 11259 | A_23_P252052 | 0.0822 | 0.8602 | |
| SRP007169 | FILIP1L | 11259 | RNAseq | 2.5999 | 0.0000 | |
| SRP008496 | FILIP1L | 11259 | RNAseq | 2.6820 | 0.0000 | |
| SRP064894 | FILIP1L | 11259 | RNAseq | -0.1658 | 0.6475 | |
| SRP133303 | FILIP1L | 11259 | RNAseq | 0.5332 | 0.1547 | |
| SRP159526 | FILIP1L | 11259 | RNAseq | -0.3551 | 0.5438 | |
| SRP193095 | FILIP1L | 11259 | RNAseq | 1.2689 | 0.0000 | |
| SRP219564 | FILIP1L | 11259 | RNAseq | -0.7515 | 0.4634 | |
| TCGA | FILIP1L | 11259 | RNAseq | -0.6276 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by FILIP1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FILIP1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FILIP1L | 11259 | 18 | 1 | 11 | |
| GSE20123 | FILIP1L | 11259 | 17 | 1 | 12 | |
| GSE43470 | FILIP1L | 11259 | 19 | 1 | 23 | |
| GSE46452 | FILIP1L | 11259 | 12 | 6 | 41 | |
| GSE47630 | FILIP1L | 11259 | 16 | 6 | 18 | |
| GSE54993 | FILIP1L | 11259 | 2 | 5 | 63 | |
| GSE54994 | FILIP1L | 11259 | 27 | 5 | 21 | |
| GSE60625 | FILIP1L | 11259 | 0 | 6 | 5 | |
| GSE74703 | FILIP1L | 11259 | 15 | 1 | 20 | |
| GSE74704 | FILIP1L | 11259 | 14 | 1 | 5 | |
| TCGA | FILIP1L | 11259 | 50 | 9 | 37 |
Total number of gains: 190; Total number of losses: 42; Total Number of normals: 256.
Somatic mutations of FILIP1L:
Generating mutation plots.
Highly correlated genes for FILIP1L:
Showing top 20/1128 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FILIP1L | FIBIN | 0.833516 | 5 | 0 | 5 |
| FILIP1L | CYP4V2 | 0.825309 | 3 | 0 | 3 |
| FILIP1L | ZEB1 | 0.823128 | 3 | 0 | 3 |
| FILIP1L | LAMA4 | 0.804908 | 12 | 0 | 12 |
| FILIP1L | FERMT2 | 0.804429 | 13 | 0 | 13 |
| FILIP1L | C11orf96 | 0.803403 | 5 | 0 | 5 |
| FILIP1L | CALD1 | 0.79582 | 13 | 0 | 13 |
| FILIP1L | DDR2 | 0.787498 | 12 | 0 | 12 |
| FILIP1L | CRISPLD2 | 0.786328 | 13 | 0 | 13 |
| FILIP1L | TMEM47 | 0.777561 | 13 | 0 | 13 |
| FILIP1L | PMP22 | 0.776837 | 13 | 0 | 12 |
| FILIP1L | TGFB1I1 | 0.77366 | 12 | 0 | 12 |
| FILIP1L | PDLIM3 | 0.771974 | 13 | 0 | 12 |
| FILIP1L | FBN1 | 0.770727 | 11 | 0 | 11 |
| FILIP1L | RHOJ | 0.768829 | 4 | 0 | 4 |
| FILIP1L | CNRIP1 | 0.768446 | 9 | 0 | 9 |
| FILIP1L | ACTA2 | 0.767051 | 13 | 0 | 13 |
| FILIP1L | DCN | 0.766099 | 12 | 0 | 12 |
| FILIP1L | ITGA1 | 0.765921 | 12 | 0 | 11 |
| FILIP1L | COL15A1 | 0.763717 | 13 | 0 | 13 |
For details and further investigation, click here
