| Full name: ring finger protein 34 | Alias Symbol: RIFF|FLJ21786|RIF | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 80196 | HGNC ID: HGNC:17297 | Ensembl Gene: ENSG00000170633 | OMIM ID: 608299 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF34 | 80196 | 219035_s_at | 0.3828 | 0.2781 | |
| GSE20347 | RNF34 | 80196 | 219035_s_at | 0.3223 | 0.0037 | |
| GSE23400 | RNF34 | 80196 | 219035_s_at | 0.3892 | 0.0000 | |
| GSE26886 | RNF34 | 80196 | 219035_s_at | -0.3022 | 0.1546 | |
| GSE29001 | RNF34 | 80196 | 219035_s_at | 0.5948 | 0.0004 | |
| GSE38129 | RNF34 | 80196 | 219035_s_at | 0.2747 | 0.0010 | |
| GSE45670 | RNF34 | 80196 | 219035_s_at | 0.4681 | 0.0001 | |
| GSE53622 | RNF34 | 80196 | 15793 | 0.4269 | 0.0000 | |
| GSE53624 | RNF34 | 80196 | 15793 | 0.5290 | 0.0000 | |
| GSE63941 | RNF34 | 80196 | 219035_s_at | 0.4244 | 0.2883 | |
| GSE77861 | RNF34 | 80196 | 219035_s_at | 0.4014 | 0.0479 | |
| GSE97050 | RNF34 | 80196 | A_23_P128396 | 0.0098 | 0.9774 | |
| SRP007169 | RNF34 | 80196 | RNAseq | 1.3364 | 0.0055 | |
| SRP008496 | RNF34 | 80196 | RNAseq | 1.2203 | 0.0022 | |
| SRP064894 | RNF34 | 80196 | RNAseq | 0.4478 | 0.0000 | |
| SRP133303 | RNF34 | 80196 | RNAseq | 0.3760 | 0.0001 | |
| SRP159526 | RNF34 | 80196 | RNAseq | 0.6149 | 0.0154 | |
| SRP193095 | RNF34 | 80196 | RNAseq | 0.1221 | 0.1316 | |
| SRP219564 | RNF34 | 80196 | RNAseq | -0.0576 | 0.8501 | |
| TCGA | RNF34 | 80196 | RNAseq | 0.0486 | 0.3577 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RNF34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF34 | 80196 | 5 | 4 | 21 | |
| GSE20123 | RNF34 | 80196 | 5 | 4 | 21 | |
| GSE43470 | RNF34 | 80196 | 2 | 2 | 39 | |
| GSE46452 | RNF34 | 80196 | 9 | 1 | 49 | |
| GSE47630 | RNF34 | 80196 | 9 | 3 | 28 | |
| GSE54993 | RNF34 | 80196 | 0 | 5 | 65 | |
| GSE54994 | RNF34 | 80196 | 6 | 7 | 40 | |
| GSE60625 | RNF34 | 80196 | 0 | 0 | 11 | |
| GSE74703 | RNF34 | 80196 | 2 | 1 | 33 | |
| GSE74704 | RNF34 | 80196 | 3 | 2 | 15 | |
| TCGA | RNF34 | 80196 | 22 | 10 | 64 |
Total number of gains: 63; Total number of losses: 39; Total Number of normals: 386.
Somatic mutations of RNF34:
Generating mutation plots.
Highly correlated genes for RNF34:
Showing top 20/1285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF34 | CRNKL1 | 0.81471 | 3 | 0 | 3 |
| RNF34 | TATDN2 | 0.803511 | 3 | 0 | 3 |
| RNF34 | RAD18 | 0.779717 | 3 | 0 | 3 |
| RNF34 | COMMD7 | 0.777988 | 3 | 0 | 3 |
| RNF34 | TMEM19 | 0.776593 | 3 | 0 | 3 |
| RNF34 | RLIM | 0.776549 | 3 | 0 | 3 |
| RNF34 | KTI12 | 0.774805 | 3 | 0 | 3 |
| RNF34 | KLHL36 | 0.754204 | 4 | 0 | 4 |
| RNF34 | KRTCAP2 | 0.754192 | 3 | 0 | 3 |
| RNF34 | SMARCE1 | 0.740104 | 3 | 0 | 3 |
| RNF34 | PRKX | 0.737508 | 3 | 0 | 3 |
| RNF34 | SPNS1 | 0.734264 | 3 | 0 | 3 |
| RNF34 | ADH5 | 0.73202 | 5 | 0 | 5 |
| RNF34 | KLHL5 | 0.72901 | 5 | 0 | 4 |
| RNF34 | UQCR10 | 0.726825 | 3 | 0 | 3 |
| RNF34 | SLC15A3 | 0.725472 | 3 | 0 | 3 |
| RNF34 | MAPKAPK5 | 0.721888 | 11 | 0 | 11 |
| RNF34 | LMBR1 | 0.721238 | 3 | 0 | 3 |
| RNF34 | GZF1 | 0.720494 | 3 | 0 | 3 |
| RNF34 | RPRD1B | 0.718634 | 4 | 0 | 3 |
For details and further investigation, click here
