| Full name: PR/SET domain 10 | Alias Symbol: KIAA1231|PFM7|MGC131802 | ||
| Type: protein-coding gene | Cytoband: 11q24.3 | ||
| Entrez ID: 56980 | HGNC ID: HGNC:13995 | Ensembl Gene: ENSG00000170325 | OMIM ID: 618319 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PRDM10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM10 | 56980 | 219515_at | -0.2402 | 0.5079 | |
| GSE20347 | PRDM10 | 56980 | 219515_at | -0.4724 | 0.0001 | |
| GSE23400 | PRDM10 | 56980 | 219515_at | -0.0342 | 0.4857 | |
| GSE26886 | PRDM10 | 56980 | 219515_at | -1.2353 | 0.0000 | |
| GSE29001 | PRDM10 | 56980 | 219515_at | -0.2682 | 0.1837 | |
| GSE38129 | PRDM10 | 56980 | 219515_at | -0.3225 | 0.0021 | |
| GSE45670 | PRDM10 | 56980 | 219515_at | -0.0571 | 0.6868 | |
| GSE53622 | PRDM10 | 56980 | 63370 | -0.3240 | 0.0000 | |
| GSE53624 | PRDM10 | 56980 | 63370 | -0.3389 | 0.0000 | |
| GSE63941 | PRDM10 | 56980 | 219515_at | -1.3597 | 0.0003 | |
| GSE77861 | PRDM10 | 56980 | 219515_at | -0.0969 | 0.5664 | |
| GSE97050 | PRDM10 | 56980 | A_32_P228699 | -0.0130 | 0.9611 | |
| SRP007169 | PRDM10 | 56980 | RNAseq | 0.3336 | 0.5517 | |
| SRP008496 | PRDM10 | 56980 | RNAseq | -0.0442 | 0.8966 | |
| SRP064894 | PRDM10 | 56980 | RNAseq | -0.5155 | 0.0580 | |
| SRP133303 | PRDM10 | 56980 | RNAseq | -0.2976 | 0.0032 | |
| SRP159526 | PRDM10 | 56980 | RNAseq | -0.6205 | 0.0023 | |
| SRP193095 | PRDM10 | 56980 | RNAseq | -0.5365 | 0.0000 | |
| SRP219564 | PRDM10 | 56980 | RNAseq | -0.4474 | 0.3093 | |
| TCGA | PRDM10 | 56980 | RNAseq | -0.0251 | 0.6478 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PRDM10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM10 | 56980 | 0 | 13 | 17 | |
| GSE20123 | PRDM10 | 56980 | 0 | 13 | 17 | |
| GSE43470 | PRDM10 | 56980 | 2 | 7 | 34 | |
| GSE46452 | PRDM10 | 56980 | 3 | 26 | 30 | |
| GSE47630 | PRDM10 | 56980 | 2 | 19 | 19 | |
| GSE54993 | PRDM10 | 56980 | 10 | 0 | 60 | |
| GSE54994 | PRDM10 | 56980 | 5 | 19 | 29 | |
| GSE60625 | PRDM10 | 56980 | 0 | 3 | 8 | |
| GSE74703 | PRDM10 | 56980 | 1 | 5 | 30 | |
| GSE74704 | PRDM10 | 56980 | 0 | 9 | 11 | |
| TCGA | PRDM10 | 56980 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of PRDM10:
Generating mutation plots.
Highly correlated genes for PRDM10:
Showing top 20/822 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM10 | ARSD | 0.788997 | 3 | 0 | 3 |
| PRDM10 | WDFY1 | 0.769248 | 3 | 0 | 3 |
| PRDM10 | SNAP23 | 0.765744 | 3 | 0 | 3 |
| PRDM10 | UBE3C | 0.765685 | 3 | 0 | 3 |
| PRDM10 | FNBP1 | 0.762927 | 3 | 0 | 3 |
| PRDM10 | SYTL4 | 0.762778 | 3 | 0 | 3 |
| PRDM10 | ZNF382 | 0.746667 | 3 | 0 | 3 |
| PRDM10 | MAU2 | 0.744313 | 4 | 0 | 4 |
| PRDM10 | ZBTB7A | 0.74427 | 4 | 0 | 4 |
| PRDM10 | CRBN | 0.741038 | 3 | 0 | 3 |
| PRDM10 | CRNKL1 | 0.739176 | 3 | 0 | 3 |
| PRDM10 | NPC1 | 0.738038 | 3 | 0 | 3 |
| PRDM10 | FYCO1 | 0.724633 | 4 | 0 | 3 |
| PRDM10 | DPY19L3 | 0.724222 | 3 | 0 | 3 |
| PRDM10 | PWWP2A | 0.721985 | 3 | 0 | 3 |
| PRDM10 | TMEM129 | 0.720047 | 3 | 0 | 3 |
| PRDM10 | CAPRIN1 | 0.704613 | 3 | 0 | 3 |
| PRDM10 | TSPO | 0.704288 | 5 | 0 | 5 |
| PRDM10 | ZNF407 | 0.70424 | 4 | 0 | 3 |
| PRDM10 | NR2F6 | 0.703492 | 3 | 0 | 3 |
For details and further investigation, click here
