| Full name: RNA binding motif protein 18 | Alias Symbol: MGC2734 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 92400 | HGNC ID: HGNC:28413 | Ensembl Gene: ENSG00000119446 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RBM18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBM18 | 92400 | 225236_at | -0.0174 | 0.9756 | |
| GSE26886 | RBM18 | 92400 | 225236_at | -0.0197 | 0.9594 | |
| GSE45670 | RBM18 | 92400 | 225236_at | 0.2278 | 0.0980 | |
| GSE53622 | RBM18 | 92400 | 28875 | 0.2326 | 0.0003 | |
| GSE53624 | RBM18 | 92400 | 28875 | 0.6079 | 0.0000 | |
| GSE63941 | RBM18 | 92400 | 225236_at | 0.2317 | 0.6265 | |
| GSE77861 | RBM18 | 92400 | 225236_at | 0.1273 | 0.6181 | |
| GSE97050 | RBM18 | 92400 | A_23_P20777 | 0.1124 | 0.6184 | |
| SRP007169 | RBM18 | 92400 | RNAseq | 0.4991 | 0.2570 | |
| SRP008496 | RBM18 | 92400 | RNAseq | 0.3636 | 0.1750 | |
| SRP064894 | RBM18 | 92400 | RNAseq | 0.3423 | 0.0124 | |
| SRP133303 | RBM18 | 92400 | RNAseq | 0.4468 | 0.0041 | |
| SRP159526 | RBM18 | 92400 | RNAseq | 0.0436 | 0.8560 | |
| SRP193095 | RBM18 | 92400 | RNAseq | -0.0118 | 0.9239 | |
| SRP219564 | RBM18 | 92400 | RNAseq | 0.0582 | 0.7783 | |
| TCGA | RBM18 | 92400 | RNAseq | -0.0466 | 0.3820 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RBM18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBM18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBM18 | 92400 | 3 | 7 | 20 | |
| GSE20123 | RBM18 | 92400 | 3 | 7 | 20 | |
| GSE43470 | RBM18 | 92400 | 6 | 3 | 34 | |
| GSE46452 | RBM18 | 92400 | 6 | 13 | 40 | |
| GSE47630 | RBM18 | 92400 | 3 | 16 | 21 | |
| GSE54993 | RBM18 | 92400 | 3 | 3 | 64 | |
| GSE54994 | RBM18 | 92400 | 9 | 10 | 34 | |
| GSE60625 | RBM18 | 92400 | 0 | 0 | 11 | |
| GSE74703 | RBM18 | 92400 | 5 | 3 | 28 | |
| GSE74704 | RBM18 | 92400 | 2 | 5 | 13 | |
| TCGA | RBM18 | 92400 | 27 | 24 | 45 |
Total number of gains: 67; Total number of losses: 91; Total Number of normals: 330.
Somatic mutations of RBM18:
Generating mutation plots.
Highly correlated genes for RBM18:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBM18 | LSM11 | 0.81256 | 3 | 0 | 3 |
| RBM18 | FAM76B | 0.807426 | 3 | 0 | 3 |
| RBM18 | EIF3G | 0.788814 | 3 | 0 | 3 |
| RBM18 | RRAS2 | 0.768978 | 3 | 0 | 3 |
| RBM18 | DHX40 | 0.762935 | 3 | 0 | 3 |
| RBM18 | CRNKL1 | 0.742823 | 3 | 0 | 3 |
| RBM18 | BBS7 | 0.741384 | 3 | 0 | 3 |
| RBM18 | ING1 | 0.739275 | 3 | 0 | 3 |
| RBM18 | KLF11 | 0.738503 | 3 | 0 | 3 |
| RBM18 | DMXL2 | 0.728018 | 3 | 0 | 3 |
| RBM18 | ELF2 | 0.725253 | 3 | 0 | 3 |
| RBM18 | ZNF510 | 0.723765 | 3 | 0 | 3 |
| RBM18 | ARL2 | 0.72367 | 3 | 0 | 3 |
| RBM18 | SAP30L | 0.722962 | 4 | 0 | 4 |
| RBM18 | JMY | 0.721192 | 4 | 0 | 3 |
| RBM18 | PRKACB | 0.719059 | 3 | 0 | 3 |
| RBM18 | SCARB2 | 0.718355 | 3 | 0 | 3 |
| RBM18 | FRYL | 0.715039 | 3 | 0 | 3 |
| RBM18 | LIPT1 | 0.714158 | 4 | 0 | 3 |
| RBM18 | USP33 | 0.712346 | 4 | 0 | 3 |
For details and further investigation, click here
