| Full name: interferon induced protein with tetratricopeptide repeats 5 | Alias Symbol: RI58 | ||
| Type: protein-coding gene | Cytoband: 10q23.31 | ||
| Entrez ID: 24138 | HGNC ID: HGNC:13328 | Ensembl Gene: ENSG00000152778 | OMIM ID: 616135 |
| Drug and gene relationship at DGIdb | |||
Expression of IFIT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFIT5 | 24138 | 203595_s_at | 0.0975 | 0.9114 | |
| GSE20347 | IFIT5 | 24138 | 203595_s_at | -0.0442 | 0.8662 | |
| GSE23400 | IFIT5 | 24138 | 203595_s_at | 0.2386 | 0.0189 | |
| GSE26886 | IFIT5 | 24138 | 203595_s_at | 0.1876 | 0.6763 | |
| GSE29001 | IFIT5 | 24138 | 203595_s_at | 0.5222 | 0.0932 | |
| GSE38129 | IFIT5 | 24138 | 203595_s_at | -0.1261 | 0.5257 | |
| GSE45670 | IFIT5 | 24138 | 203595_s_at | 0.6260 | 0.0449 | |
| GSE53622 | IFIT5 | 24138 | 108150 | 0.2209 | 0.0599 | |
| GSE53624 | IFIT5 | 24138 | 108150 | 0.4006 | 0.0000 | |
| GSE63941 | IFIT5 | 24138 | 203595_s_at | -1.6245 | 0.1232 | |
| GSE77861 | IFIT5 | 24138 | 203595_s_at | 0.1482 | 0.6689 | |
| GSE97050 | IFIT5 | 24138 | A_24_P30194 | -0.0077 | 0.9857 | |
| SRP007169 | IFIT5 | 24138 | RNAseq | -0.1738 | 0.6605 | |
| SRP008496 | IFIT5 | 24138 | RNAseq | 0.2451 | 0.4954 | |
| SRP064894 | IFIT5 | 24138 | RNAseq | 0.5869 | 0.0065 | |
| SRP133303 | IFIT5 | 24138 | RNAseq | 0.4851 | 0.0209 | |
| SRP159526 | IFIT5 | 24138 | RNAseq | -0.1235 | 0.8058 | |
| SRP193095 | IFIT5 | 24138 | RNAseq | 0.5045 | 0.0015 | |
| SRP219564 | IFIT5 | 24138 | RNAseq | 0.1685 | 0.6833 | |
| TCGA | IFIT5 | 24138 | RNAseq | 0.1067 | 0.2382 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFIT5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFIT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFIT5 | 24138 | 2 | 7 | 21 | |
| GSE20123 | IFIT5 | 24138 | 2 | 6 | 22 | |
| GSE43470 | IFIT5 | 24138 | 0 | 8 | 35 | |
| GSE46452 | IFIT5 | 24138 | 0 | 11 | 48 | |
| GSE47630 | IFIT5 | 24138 | 2 | 14 | 24 | |
| GSE54993 | IFIT5 | 24138 | 7 | 0 | 63 | |
| GSE54994 | IFIT5 | 24138 | 1 | 11 | 41 | |
| GSE60625 | IFIT5 | 24138 | 0 | 0 | 11 | |
| GSE74703 | IFIT5 | 24138 | 0 | 6 | 30 | |
| GSE74704 | IFIT5 | 24138 | 1 | 4 | 15 | |
| TCGA | IFIT5 | 24138 | 7 | 27 | 62 |
Total number of gains: 22; Total number of losses: 94; Total Number of normals: 372.
Somatic mutations of IFIT5:
Generating mutation plots.
Highly correlated genes for IFIT5:
Showing top 20/217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFIT5 | RBM39 | 0.797525 | 3 | 0 | 3 |
| IFIT5 | FBXL14 | 0.76984 | 3 | 0 | 3 |
| IFIT5 | NNT | 0.747983 | 3 | 0 | 3 |
| IFIT5 | KLHL15 | 0.734494 | 3 | 0 | 3 |
| IFIT5 | SLC35B3 | 0.731634 | 3 | 0 | 3 |
| IFIT5 | ZNF225 | 0.730996 | 3 | 0 | 3 |
| IFIT5 | LCOR | 0.72972 | 3 | 0 | 3 |
| IFIT5 | IFIT1 | 0.728644 | 13 | 0 | 12 |
| IFIT5 | C5orf51 | 0.728189 | 3 | 0 | 3 |
| IFIT5 | MASTL | 0.722726 | 3 | 0 | 3 |
| IFIT5 | CRNKL1 | 0.722167 | 3 | 0 | 3 |
| IFIT5 | MYH3 | 0.717022 | 3 | 0 | 3 |
| IFIT5 | ZNF136 | 0.714907 | 4 | 0 | 3 |
| IFIT5 | KLHL21 | 0.71288 | 3 | 0 | 3 |
| IFIT5 | TMEM181 | 0.709166 | 3 | 0 | 3 |
| IFIT5 | LRRC8B | 0.707765 | 3 | 0 | 3 |
| IFIT5 | STAMBPL1 | 0.701957 | 5 | 0 | 5 |
| IFIT5 | EIF3C | 0.701634 | 3 | 0 | 3 |
| IFIT5 | SP3 | 0.699638 | 3 | 0 | 3 |
| IFIT5 | GRB2 | 0.698047 | 3 | 0 | 3 |
For details and further investigation, click here
