| Full name: lymphoid restricted membrane protein | Alias Symbol: JAW1 | ||
| Type: protein-coding gene | Cytoband: 12p12.1 | ||
| Entrez ID: 4033 | HGNC ID: HGNC:6690 | Ensembl Gene: ENSG00000118308 | OMIM ID: 602003 |
| Drug and gene relationship at DGIdb | |||
Expression of LRMP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRMP | 4033 | 204674_at | 0.2155 | 0.8911 | |
| GSE20347 | LRMP | 4033 | 204674_at | -0.7352 | 0.0090 | |
| GSE23400 | LRMP | 4033 | 204674_at | -0.5122 | 0.0000 | |
| GSE26886 | LRMP | 4033 | 204674_at | -1.7034 | 0.0137 | |
| GSE29001 | LRMP | 4033 | 204674_at | -0.8092 | 0.0065 | |
| GSE38129 | LRMP | 4033 | 204674_at | -0.8276 | 0.0000 | |
| GSE45670 | LRMP | 4033 | 204674_at | -0.8579 | 0.0150 | |
| GSE53622 | LRMP | 4033 | 10857 | -0.9298 | 0.0000 | |
| GSE53624 | LRMP | 4033 | 10857 | -1.8110 | 0.0000 | |
| GSE63941 | LRMP | 4033 | 204674_at | 0.5621 | 0.5297 | |
| GSE77861 | LRMP | 4033 | 204674_at | -0.8714 | 0.0027 | |
| GSE97050 | LRMP | 4033 | A_23_P98910 | 0.1266 | 0.6282 | |
| SRP007169 | LRMP | 4033 | RNAseq | -2.2868 | 0.0007 | |
| SRP064894 | LRMP | 4033 | RNAseq | -0.9688 | 0.0010 | |
| SRP133303 | LRMP | 4033 | RNAseq | -0.3578 | 0.2775 | |
| SRP159526 | LRMP | 4033 | RNAseq | -1.6822 | 0.0579 | |
| SRP193095 | LRMP | 4033 | RNAseq | -0.5861 | 0.0375 | |
| SRP219564 | LRMP | 4033 | RNAseq | -1.6061 | 0.0594 | |
| TCGA | LRMP | 4033 | RNAseq | -0.4031 | 0.1622 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by LRMP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRMP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRMP | 4033 | 10 | 1 | 19 | |
| GSE20123 | LRMP | 4033 | 10 | 1 | 19 | |
| GSE43470 | LRMP | 4033 | 9 | 4 | 30 | |
| GSE46452 | LRMP | 4033 | 10 | 1 | 48 | |
| GSE47630 | LRMP | 4033 | 15 | 0 | 25 | |
| GSE54993 | LRMP | 4033 | 0 | 9 | 61 | |
| GSE54994 | LRMP | 4033 | 11 | 2 | 40 | |
| GSE60625 | LRMP | 4033 | 0 | 1 | 10 | |
| GSE74703 | LRMP | 4033 | 9 | 3 | 24 | |
| GSE74704 | LRMP | 4033 | 6 | 1 | 13 | |
| TCGA | LRMP | 4033 | 43 | 4 | 49 |
Total number of gains: 123; Total number of losses: 27; Total Number of normals: 338.
Somatic mutations of LRMP:
Generating mutation plots.
Highly correlated genes for LRMP:
Showing top 20/1083 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRMP | RBM20 | 0.761126 | 4 | 0 | 4 |
| LRMP | COPZ1 | 0.750137 | 4 | 0 | 4 |
| LRMP | ARFGAP2 | 0.73945 | 3 | 0 | 3 |
| LRMP | CRNKL1 | 0.726647 | 3 | 0 | 3 |
| LRMP | DUSP16 | 0.723336 | 4 | 0 | 3 |
| LRMP | TM7SF3 | 0.718298 | 3 | 0 | 3 |
| LRMP | PTPRF | 0.718003 | 3 | 0 | 3 |
| LRMP | C2orf16 | 0.698888 | 3 | 0 | 3 |
| LRMP | OMA1 | 0.698645 | 4 | 0 | 4 |
| LRMP | KBTBD4 | 0.698468 | 3 | 0 | 3 |
| LRMP | DR1 | 0.694456 | 3 | 0 | 3 |
| LRMP | ZNF606 | 0.685371 | 3 | 0 | 3 |
| LRMP | BAG6 | 0.681242 | 3 | 0 | 3 |
| LRMP | HDHD2 | 0.681105 | 4 | 0 | 4 |
| LRMP | ARHGAP15 | 0.679315 | 4 | 0 | 4 |
| LRMP | LRRC41 | 0.679016 | 3 | 0 | 3 |
| LRMP | SUFU | 0.675219 | 3 | 0 | 3 |
| LRMP | YTHDF2 | 0.674304 | 3 | 0 | 3 |
| LRMP | PLAC8 | 0.672557 | 11 | 0 | 9 |
| LRMP | LRRK2 | 0.671458 | 6 | 0 | 6 |
For details and further investigation, click here
