| Full name: coiled-coil domain containing 125 | Alias Symbol: KENAE | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 202243 | HGNC ID: HGNC:28924 | Ensembl Gene: ENSG00000183323 | OMIM ID: 613781 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC125:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC125 | 202243 | 1553542_at | -0.3676 | 0.3711 | |
| GSE26886 | CCDC125 | 202243 | 1553542_at | -0.9114 | 0.0001 | |
| GSE45670 | CCDC125 | 202243 | 1553542_at | -0.0739 | 0.8183 | |
| GSE53622 | CCDC125 | 202243 | 32371 | -0.8794 | 0.0000 | |
| GSE53624 | CCDC125 | 202243 | 32371 | -0.9061 | 0.0000 | |
| GSE63941 | CCDC125 | 202243 | 229082_at | 0.7432 | 0.1338 | |
| GSE77861 | CCDC125 | 202243 | 1553542_at | -0.3210 | 0.0602 | |
| GSE97050 | CCDC125 | 202243 | A_23_P432591 | -0.1315 | 0.7675 | |
| SRP007169 | CCDC125 | 202243 | RNAseq | -1.5098 | 0.0002 | |
| SRP008496 | CCDC125 | 202243 | RNAseq | -1.6180 | 0.0000 | |
| SRP064894 | CCDC125 | 202243 | RNAseq | -0.7689 | 0.0000 | |
| SRP133303 | CCDC125 | 202243 | RNAseq | -0.5680 | 0.0041 | |
| SRP159526 | CCDC125 | 202243 | RNAseq | -1.0452 | 0.0000 | |
| SRP193095 | CCDC125 | 202243 | RNAseq | -0.7588 | 0.0000 | |
| SRP219564 | CCDC125 | 202243 | RNAseq | -0.8395 | 0.0019 | |
| TCGA | CCDC125 | 202243 | RNAseq | -0.5100 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CCDC125 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC125:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC125 | 202243 | 1 | 13 | 16 | |
| GSE20123 | CCDC125 | 202243 | 1 | 13 | 16 | |
| GSE43470 | CCDC125 | 202243 | 1 | 12 | 30 | |
| GSE46452 | CCDC125 | 202243 | 0 | 28 | 31 | |
| GSE47630 | CCDC125 | 202243 | 2 | 17 | 21 | |
| GSE54993 | CCDC125 | 202243 | 8 | 1 | 61 | |
| GSE54994 | CCDC125 | 202243 | 1 | 21 | 31 | |
| GSE60625 | CCDC125 | 202243 | 0 | 0 | 11 | |
| GSE74703 | CCDC125 | 202243 | 1 | 9 | 26 | |
| GSE74704 | CCDC125 | 202243 | 1 | 6 | 13 | |
| TCGA | CCDC125 | 202243 | 4 | 51 | 41 |
Total number of gains: 20; Total number of losses: 171; Total Number of normals: 297.
Somatic mutations of CCDC125:
Generating mutation plots.
Highly correlated genes for CCDC125:
Showing top 20/768 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC125 | RASAL1 | 0.695157 | 6 | 0 | 6 |
| CCDC125 | CAPN5 | 0.693315 | 6 | 0 | 6 |
| CCDC125 | SFTA2 | 0.691912 | 4 | 0 | 4 |
| CCDC125 | ACAA1 | 0.689572 | 5 | 0 | 5 |
| CCDC125 | RMND5B | 0.683147 | 7 | 0 | 6 |
| CCDC125 | PPDPF | 0.678262 | 6 | 0 | 6 |
| CCDC125 | C5orf66-AS1 | 0.676996 | 6 | 0 | 6 |
| CCDC125 | ZFAND2B | 0.676366 | 7 | 0 | 7 |
| CCDC125 | ICA1 | 0.674761 | 6 | 0 | 5 |
| CCDC125 | OCLN | 0.665099 | 7 | 0 | 6 |
| CCDC125 | FBXL16 | 0.66084 | 6 | 0 | 5 |
| CCDC125 | SMIM5 | 0.660561 | 6 | 0 | 6 |
| CCDC125 | TTC9 | 0.656143 | 7 | 0 | 7 |
| CCDC125 | PTK6 | 0.655438 | 7 | 0 | 7 |
| CCDC125 | TRNP1 | 0.655241 | 6 | 0 | 6 |
| CCDC125 | BLNK | 0.654753 | 8 | 0 | 8 |
| CCDC125 | RAB25 | 0.654461 | 8 | 0 | 7 |
| CCDC125 | DEGS2 | 0.653698 | 6 | 0 | 5 |
| CCDC125 | PPP1R3C | 0.650609 | 6 | 0 | 6 |
| CCDC125 | PCBP1-AS1 | 0.650421 | 3 | 0 | 3 |
For details and further investigation, click here
