CSF2RB

 

Full name: colony stimulating factor 2 receptor beta common subunit Alias Symbol: IL5RB|CD131|betaGMR
Type: protein-coding gene Cytoband: 22q12.3
Entrez ID: 1439 HGNC ID: HGNC:2436 Ensembl Gene: ENSG00000100368 OMIM ID: 138981
Drug and gene relationship at DGIdb

 

CSF2RB involved pathways:

KEGG pathway Description View
hsa04210Apoptosis
hsa04630Jak-STAT signaling pathway

 

Expression of CSF2RB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CSF2RB 1439 205159_at -0.1512 0.9268
GSE20347 CSF2RB 1439 205159_at 0.1821 0.6072
GSE23400 CSF2RB 1439 205159_at 0.1307 0.4087
GSE26886 CSF2RB 1439 205159_at -1.2362 0.0652
GSE29001 CSF2RB 1439 205159_at 0.4194 0.2615
GSE38129 CSF2RB 1439 205159_at 0.0301 0.9390
GSE45670 CSF2RB 1439 205159_at -0.3484 0.4610
GSE53622 CSF2RB 1439 19263 0.1555 0.2672
GSE53624 CSF2RB 1439 41849 0.0998 0.4526
GSE63941 CSF2RB 1439 205159_at 0.0778 0.5390
GSE77861 CSF2RB 1439 205159_at 0.4270 0.3073
GSE97050 CSF2RB 1439 A_33_P3341442 0.9144 0.2019
SRP007169 CSF2RB 1439 RNAseq 0.8937 0.1603
SRP008496 CSF2RB 1439 RNAseq 0.5175 0.2033
SRP064894 CSF2RB 1439 RNAseq 0.1652 0.6272
SRP133303 CSF2RB 1439 RNAseq 0.0445 0.8257
SRP159526 CSF2RB 1439 RNAseq 0.4301 0.4866
SRP193095 CSF2RB 1439 RNAseq 0.8960 0.0062
SRP219564 CSF2RB 1439 RNAseq 0.3739 0.4470
TCGA CSF2RB 1439 RNAseq -0.1589 0.2265

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CSF2RB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CSF2RB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CSF2RB 1439 6 6 18
GSE20123 CSF2RB 1439 6 5 19
GSE43470 CSF2RB 1439 4 6 33
GSE46452 CSF2RB 1439 31 1 27
GSE47630 CSF2RB 1439 8 5 27
GSE54993 CSF2RB 1439 3 6 61
GSE54994 CSF2RB 1439 10 9 34
GSE60625 CSF2RB 1439 5 0 6
GSE74703 CSF2RB 1439 4 4 28
GSE74704 CSF2RB 1439 3 2 15
TCGA CSF2RB 1439 27 16 53

Total number of gains: 107; Total number of losses: 60; Total Number of normals: 321.  

 

Somatic mutations of CSF2RB:

 

Generating mutation plots.

 

Highly correlated genes for CSF2RB:

 

Showing top 20/374 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CSF2RBDOK30.773359404
CSF2RBSELL0.758254909
CSF2RBCD530.754519807
CSF2RBEVI2B0.7485241009
CSF2RBSLC16A100.734818303
CSF2RBCORO1A0.73310810010
CSF2RBP2RY80.728101403
CSF2RBBTK0.728026404
CSF2RBIRF80.72609610010
CSF2RBST8SIA40.725884606
CSF2RBMPEG10.724472606
CSF2RBPTPRC0.720967908
CSF2RBPIGS0.716658303
CSF2RBCCL30.708609303
CSF2RBLAPTM50.7004971009
CSF2RBCCL190.699133808
CSF2RBSLAMF60.696886404
CSF2RBMYO1F0.695712909
CSF2RBC1orf1620.690308606
CSF2RBYIF1B0.687888303

For details and further investigation, click here