| Full name: macrophage expressed 1 | Alias Symbol: MPG1 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 219972 | HGNC ID: HGNC:29619 | Ensembl Gene: ENSG00000197629 | OMIM ID: 610390 |
| Drug and gene relationship at DGIdb | |||
Expression of MPEG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPEG1 | 219972 | 226818_at | -0.4146 | 0.8023 | |
| GSE26886 | MPEG1 | 219972 | 226841_at | -0.7931 | 0.0209 | |
| GSE45670 | MPEG1 | 219972 | 226818_at | -0.7424 | 0.1036 | |
| GSE53622 | MPEG1 | 219972 | 16806 | -0.4414 | 0.0045 | |
| GSE53624 | MPEG1 | 219972 | 16806 | -0.4067 | 0.0099 | |
| GSE63941 | MPEG1 | 219972 | 226841_at | -0.0720 | 0.6909 | |
| GSE77861 | MPEG1 | 219972 | 226818_at | -0.0709 | 0.8187 | |
| GSE97050 | MPEG1 | 219972 | A_33_P3212232 | 0.4549 | 0.2502 | |
| SRP007169 | MPEG1 | 219972 | RNAseq | 0.6996 | 0.2654 | |
| SRP008496 | MPEG1 | 219972 | RNAseq | 0.5206 | 0.1916 | |
| SRP064894 | MPEG1 | 219972 | RNAseq | 0.1908 | 0.5669 | |
| SRP133303 | MPEG1 | 219972 | RNAseq | -0.3616 | 0.2115 | |
| SRP159526 | MPEG1 | 219972 | RNAseq | -0.0790 | 0.9291 | |
| SRP193095 | MPEG1 | 219972 | RNAseq | 0.0484 | 0.8165 | |
| SRP219564 | MPEG1 | 219972 | RNAseq | 0.9320 | 0.1673 | |
| TCGA | MPEG1 | 219972 | RNAseq | -0.1162 | 0.3983 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPEG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPEG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPEG1 | 219972 | 1 | 5 | 24 | |
| GSE20123 | MPEG1 | 219972 | 1 | 5 | 24 | |
| GSE43470 | MPEG1 | 219972 | 1 | 5 | 37 | |
| GSE46452 | MPEG1 | 219972 | 9 | 4 | 46 | |
| GSE47630 | MPEG1 | 219972 | 3 | 8 | 29 | |
| GSE54993 | MPEG1 | 219972 | 3 | 0 | 67 | |
| GSE54994 | MPEG1 | 219972 | 5 | 6 | 42 | |
| GSE60625 | MPEG1 | 219972 | 0 | 3 | 8 | |
| GSE74703 | MPEG1 | 219972 | 1 | 3 | 32 | |
| GSE74704 | MPEG1 | 219972 | 1 | 4 | 15 | |
| TCGA | MPEG1 | 219972 | 13 | 10 | 73 |
Total number of gains: 38; Total number of losses: 53; Total Number of normals: 397.
Somatic mutations of MPEG1:
Generating mutation plots.
Highly correlated genes for MPEG1:
Showing top 20/517 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPEG1 | FLI1 | 0.849306 | 6 | 0 | 6 |
| MPEG1 | CYBB | 0.846943 | 6 | 0 | 6 |
| MPEG1 | GIMAP6 | 0.846644 | 6 | 0 | 6 |
| MPEG1 | GIMAP4 | 0.831174 | 6 | 0 | 6 |
| MPEG1 | GIMAP5 | 0.829605 | 3 | 0 | 3 |
| MPEG1 | DOCK2 | 0.814775 | 5 | 0 | 5 |
| MPEG1 | EBI3 | 0.81111 | 3 | 0 | 3 |
| MPEG1 | C1orf162 | 0.809567 | 6 | 0 | 6 |
| MPEG1 | TMEM176B | 0.804871 | 6 | 0 | 6 |
| MPEG1 | RNASE6 | 0.803659 | 4 | 0 | 4 |
| MPEG1 | CD37 | 0.80055 | 4 | 0 | 4 |
| MPEG1 | CCR2 | 0.796913 | 6 | 0 | 6 |
| MPEG1 | TNFAIP8L2 | 0.791413 | 5 | 0 | 5 |
| MPEG1 | CTSS | 0.79013 | 5 | 0 | 5 |
| MPEG1 | ATP8B4 | 0.787693 | 6 | 0 | 5 |
| MPEG1 | GIMAP7 | 0.787559 | 6 | 0 | 6 |
| MPEG1 | GPR34 | 0.786469 | 7 | 0 | 7 |
| MPEG1 | MS4A6A | 0.786283 | 7 | 0 | 6 |
| MPEG1 | CSF1R | 0.783145 | 7 | 0 | 7 |
| MPEG1 | HLA-DOA | 0.779398 | 4 | 0 | 4 |
For details and further investigation, click here
