LAPTM5

 

Full name: lysosomal protein transmembrane 5 Alias Symbol: 
Type: protein-coding gene Cytoband: 1p35.2
Entrez ID: 7805 HGNC ID: HGNC:29612 Ensembl Gene: ENSG00000162511 OMIM ID: 601476
Drug and gene relationship at DGIdb

 

Expression of LAPTM5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LAPTM5 7805 201721_s_at 0.5289 0.7140
GSE20347 LAPTM5 7805 201721_s_at 0.1956 0.4495
GSE23400 LAPTM5 7805 201721_s_at 0.5723 0.0001
GSE26886 LAPTM5 7805 201721_s_at -1.0273 0.0581
GSE29001 LAPTM5 7805 201721_s_at 0.5799 0.2622
GSE38129 LAPTM5 7805 201721_s_at 0.3303 0.2566
GSE45670 LAPTM5 7805 201721_s_at -0.2612 0.4607
GSE53622 LAPTM5 7805 42662 0.7441 0.0000
GSE53624 LAPTM5 7805 42662 0.4289 0.0012
GSE63941 LAPTM5 7805 201721_s_at 0.3208 0.2844
GSE77861 LAPTM5 7805 201721_s_at 0.2094 0.5803
GSE97050 LAPTM5 7805 A_23_P86283 1.6002 0.0635
SRP008496 LAPTM5 7805 RNAseq 1.6938 0.0006
SRP064894 LAPTM5 7805 RNAseq 1.8251 0.0000
SRP133303 LAPTM5 7805 RNAseq 0.8471 0.0002
SRP159526 LAPTM5 7805 RNAseq -0.3320 0.6632
SRP193095 LAPTM5 7805 RNAseq 0.5959 0.0021
SRP219564 LAPTM5 7805 RNAseq 1.5306 0.0028
TCGA LAPTM5 7805 RNAseq 0.2857 0.0027

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by LAPTM5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LAPTM5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LAPTM5 7805 0 6 24
GSE20123 LAPTM5 7805 0 5 25
GSE43470 LAPTM5 7805 3 6 34
GSE46452 LAPTM5 7805 5 1 53
GSE47630 LAPTM5 7805 8 3 29
GSE54993 LAPTM5 7805 1 1 68
GSE54994 LAPTM5 7805 10 3 40
GSE60625 LAPTM5 7805 0 0 11
GSE74703 LAPTM5 7805 2 4 30
GSE74704 LAPTM5 7805 0 0 20
TCGA LAPTM5 7805 13 18 65

Total number of gains: 42; Total number of losses: 47; Total Number of normals: 399.  

 

Somatic mutations of LAPTM5:

 

Generating mutation plots.

 

Highly correlated genes for LAPTM5:

 

Showing top 20/567 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LAPTM5CD530.8601441009
LAPTM5CD840.838161909
LAPTM5MS4A70.821069303
LAPTM5TYROBP0.8152712012
LAPTM5EVI2B0.81108111011
LAPTM5ITGB20.80370312011
LAPTM5CYTIP0.788894909
LAPTM5C1QA0.78154412012
LAPTM5C1QC0.777166808
LAPTM5C1orf1620.77548707
LAPTM5CERKL0.759505303
LAPTM5PSMB8-AS10.754136404
LAPTM5C1QB0.75331812011
LAPTM5ARHGDIB0.75281410010
LAPTM5HLA-DMB0.7518312012
LAPTM5SNX200.740354707
LAPTM5SRGN0.73985712011
LAPTM5HLA-DMA0.73940712011
LAPTM5CORO1A0.73909611011
LAPTM5PTPRC0.7380611009

For details and further investigation, click here