| Full name: ecotropic viral integration site 2B | Alias Symbol: D17S376|EVDB|CD361 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 2124 | HGNC ID: HGNC:3500 | Ensembl Gene: ENSG00000185862 | OMIM ID: 158381 |
| Drug and gene relationship at DGIdb | |||
Expression of EVI2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EVI2B | 2124 | 211742_s_at | 0.2344 | 0.9080 | |
| GSE20347 | EVI2B | 2124 | 211742_s_at | -0.2080 | 0.5544 | |
| GSE23400 | EVI2B | 2124 | 211742_s_at | 0.1508 | 0.0831 | |
| GSE26886 | EVI2B | 2124 | 211742_s_at | -0.6437 | 0.1394 | |
| GSE29001 | EVI2B | 2124 | 211742_s_at | 0.1643 | 0.6880 | |
| GSE38129 | EVI2B | 2124 | 211742_s_at | -0.3724 | 0.2375 | |
| GSE45670 | EVI2B | 2124 | 211742_s_at | -0.7074 | 0.1002 | |
| GSE53622 | EVI2B | 2124 | 10375 | -0.0415 | 0.7909 | |
| GSE53624 | EVI2B | 2124 | 10375 | -0.3757 | 0.0152 | |
| GSE63941 | EVI2B | 2124 | 211742_s_at | -0.5203 | 0.3339 | |
| GSE77861 | EVI2B | 2124 | 211742_s_at | -0.0717 | 0.4961 | |
| GSE97050 | EVI2B | 2124 | A_23_P66694 | 0.7283 | 0.1399 | |
| SRP007169 | EVI2B | 2124 | RNAseq | 1.2522 | 0.0954 | |
| SRP008496 | EVI2B | 2124 | RNAseq | 0.9543 | 0.0611 | |
| SRP064894 | EVI2B | 2124 | RNAseq | 0.6013 | 0.0809 | |
| SRP133303 | EVI2B | 2124 | RNAseq | 0.1450 | 0.5220 | |
| SRP159526 | EVI2B | 2124 | RNAseq | -0.3793 | 0.6863 | |
| SRP193095 | EVI2B | 2124 | RNAseq | 0.1746 | 0.4696 | |
| SRP219564 | EVI2B | 2124 | RNAseq | 0.8273 | 0.0627 | |
| TCGA | EVI2B | 2124 | RNAseq | -0.0562 | 0.6840 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EVI2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EVI2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EVI2B | 2124 | 7 | 3 | 20 | |
| GSE20123 | EVI2B | 2124 | 8 | 3 | 19 | |
| GSE43470 | EVI2B | 2124 | 0 | 1 | 42 | |
| GSE46452 | EVI2B | 2124 | 33 | 1 | 25 | |
| GSE47630 | EVI2B | 2124 | 7 | 1 | 32 | |
| GSE54993 | EVI2B | 2124 | 2 | 3 | 65 | |
| GSE54994 | EVI2B | 2124 | 7 | 6 | 40 | |
| GSE60625 | EVI2B | 2124 | 4 | 0 | 7 | |
| GSE74703 | EVI2B | 2124 | 0 | 1 | 35 | |
| GSE74704 | EVI2B | 2124 | 6 | 2 | 12 | |
| TCGA | EVI2B | 2124 | 20 | 10 | 66 |
Total number of gains: 94; Total number of losses: 31; Total Number of normals: 363.
Somatic mutations of EVI2B:
Generating mutation plots.
Highly correlated genes for EVI2B:
Showing top 20/489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EVI2B | CD53 | 0.851135 | 10 | 0 | 10 |
| EVI2B | PTPRC | 0.828547 | 10 | 0 | 10 |
| EVI2B | CYTIP | 0.813717 | 10 | 0 | 10 |
| EVI2B | EVI2A | 0.811652 | 10 | 0 | 10 |
| EVI2B | LAPTM5 | 0.811081 | 11 | 0 | 11 |
| EVI2B | CD48 | 0.802709 | 11 | 0 | 10 |
| EVI2B | ZC3H12D | 0.802429 | 3 | 0 | 3 |
| EVI2B | SNX20 | 0.787073 | 7 | 0 | 7 |
| EVI2B | PIK3R5 | 0.785587 | 5 | 0 | 5 |
| EVI2B | C1orf162 | 0.783098 | 7 | 0 | 7 |
| EVI2B | DOCK2 | 0.779821 | 11 | 0 | 11 |
| EVI2B | IRF8 | 0.774579 | 12 | 0 | 11 |
| EVI2B | CD37 | 0.759743 | 10 | 0 | 9 |
| EVI2B | GMFG | 0.757588 | 11 | 0 | 11 |
| EVI2B | CORO1A | 0.753974 | 12 | 0 | 11 |
| EVI2B | CCR4 | 0.751515 | 3 | 0 | 3 |
| EVI2B | TAGAP | 0.751016 | 6 | 0 | 5 |
| EVI2B | PARVG | 0.7499 | 7 | 0 | 6 |
| EVI2B | CD84 | 0.749578 | 11 | 0 | 10 |
| EVI2B | CSF2RB | 0.748524 | 10 | 0 | 9 |
For details and further investigation, click here
