| Full name: chondroitin sulfate proteoglycan 4 | Alias Symbol: MCSPG|MEL-CSPG|MSK16|NG2|MCSP|HMW-MAA | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 1464 | HGNC ID: HGNC:2466 | Ensembl Gene: ENSG00000173546 | OMIM ID: 601172 |
| Drug and gene relationship at DGIdb | |||
Expression of CSPG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSPG4 | 1464 | 214297_at | 0.0553 | 0.9767 | |
| GSE20347 | CSPG4 | 1464 | 214297_at | 0.8623 | 0.0220 | |
| GSE23400 | CSPG4 | 1464 | 214297_at | 0.2648 | 0.1592 | |
| GSE26886 | CSPG4 | 1464 | 204736_s_at | 1.2580 | 0.0001 | |
| GSE29001 | CSPG4 | 1464 | 214297_at | 1.9576 | 0.0020 | |
| GSE38129 | CSPG4 | 1464 | 204736_s_at | 0.0699 | 0.8071 | |
| GSE45670 | CSPG4 | 1464 | 204736_s_at | -0.2871 | 0.3641 | |
| GSE53622 | CSPG4 | 1464 | 42330 | 0.4340 | 0.0577 | |
| GSE53624 | CSPG4 | 1464 | 42330 | 0.6824 | 0.0000 | |
| GSE63941 | CSPG4 | 1464 | 214297_at | -0.3641 | 0.5851 | |
| GSE77861 | CSPG4 | 1464 | 204736_s_at | 0.0989 | 0.5226 | |
| GSE97050 | CSPG4 | A_21_P0011330 | -0.4035 | 0.2557 | ||
| SRP007169 | CSPG4 | 1464 | RNAseq | 3.6968 | 0.0000 | |
| SRP008496 | CSPG4 | 1464 | RNAseq | 5.0854 | 0.0000 | |
| SRP064894 | CSPG4 | 1464 | RNAseq | 1.1069 | 0.0023 | |
| SRP133303 | CSPG4 | 1464 | RNAseq | 0.5508 | 0.2232 | |
| SRP193095 | CSPG4 | 1464 | RNAseq | 2.5484 | 0.0000 | |
| SRP219564 | CSPG4 | 1464 | RNAseq | -0.2273 | 0.7964 | |
| TCGA | CSPG4 | 1464 | RNAseq | -0.1964 | 0.2164 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by CSPG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSPG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSPG4 | 1464 | 8 | 1 | 21 | |
| GSE20123 | CSPG4 | 1464 | 8 | 1 | 21 | |
| GSE43470 | CSPG4 | 1464 | 4 | 6 | 33 | |
| GSE46452 | CSPG4 | 1464 | 3 | 7 | 49 | |
| GSE47630 | CSPG4 | 1464 | 8 | 10 | 22 | |
| GSE54993 | CSPG4 | 1464 | 5 | 6 | 59 | |
| GSE54994 | CSPG4 | 1464 | 5 | 6 | 42 | |
| GSE60625 | CSPG4 | 1464 | 4 | 0 | 7 | |
| GSE74703 | CSPG4 | 1464 | 4 | 3 | 29 | |
| GSE74704 | CSPG4 | 1464 | 4 | 1 | 15 | |
| TCGA | CSPG4 | 1464 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of CSPG4:
Generating mutation plots.
Highly correlated genes for CSPG4:
Showing top 20/332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSPG4 | OTOGL | 0.756578 | 3 | 0 | 3 |
| CSPG4 | P2RX2 | 0.685115 | 3 | 0 | 3 |
| CSPG4 | ABRA | 0.684201 | 3 | 0 | 3 |
| CSPG4 | THRA | 0.680095 | 4 | 0 | 4 |
| CSPG4 | COPRS | 0.679802 | 3 | 0 | 3 |
| CSPG4 | ENKD1 | 0.670203 | 3 | 0 | 3 |
| CSPG4 | NBPF20 | 0.669146 | 3 | 0 | 3 |
| CSPG4 | SLC22A17 | 0.653764 | 7 | 0 | 6 |
| CSPG4 | ATP10A | 0.641056 | 4 | 0 | 3 |
| CSPG4 | ZHX2 | 0.639893 | 3 | 0 | 3 |
| CSPG4 | ADAMTSL1 | 0.639493 | 3 | 0 | 3 |
| CSPG4 | CITED1 | 0.638397 | 4 | 0 | 4 |
| CSPG4 | NTMT1 | 0.635701 | 3 | 0 | 3 |
| CSPG4 | PPP1R12C | 0.634799 | 5 | 0 | 5 |
| CSPG4 | DHX37 | 0.633414 | 3 | 0 | 3 |
| CSPG4 | ACSF3 | 0.631397 | 3 | 0 | 3 |
| CSPG4 | TTLL7 | 0.631303 | 7 | 0 | 7 |
| CSPG4 | ARMCX2 | 0.628272 | 4 | 0 | 4 |
| CSPG4 | WNT9A | 0.626483 | 3 | 0 | 3 |
| CSPG4 | TCOF1 | 0.625242 | 3 | 0 | 3 |
For details and further investigation, click here
