| Full name: tubulin tyrosine ligase like 7 | Alias Symbol: FLJ23033 | ||
| Type: protein-coding gene | Cytoband: 1p31.1 | ||
| Entrez ID: 79739 | HGNC ID: HGNC:26242 | Ensembl Gene: ENSG00000137941 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTLL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTLL7 | 79739 | 219882_at | -0.7891 | 0.3990 | |
| GSE20347 | TTLL7 | 79739 | 219882_at | 0.1956 | 0.2726 | |
| GSE23400 | TTLL7 | 79739 | 219882_at | -0.0423 | 0.4285 | |
| GSE26886 | TTLL7 | 79739 | 219882_at | 0.9000 | 0.0046 | |
| GSE29001 | TTLL7 | 79739 | 219882_at | 0.2381 | 0.0966 | |
| GSE38129 | TTLL7 | 79739 | 219882_at | -0.0633 | 0.8349 | |
| GSE45670 | TTLL7 | 79739 | 219882_at | -0.4297 | 0.1656 | |
| GSE53622 | TTLL7 | 79739 | 33444 | -1.4078 | 0.0000 | |
| GSE53624 | TTLL7 | 79739 | 33444 | -0.5347 | 0.0000 | |
| GSE63941 | TTLL7 | 79739 | 219882_at | -1.3473 | 0.1243 | |
| GSE77861 | TTLL7 | 79739 | 219882_at | 0.1355 | 0.3476 | |
| GSE97050 | TTLL7 | 79739 | A_33_P3348164 | -1.1847 | 0.1647 | |
| SRP007169 | TTLL7 | 79739 | RNAseq | 1.2991 | 0.0697 | |
| SRP008496 | TTLL7 | 79739 | RNAseq | 2.0160 | 0.0000 | |
| SRP064894 | TTLL7 | 79739 | RNAseq | -0.3453 | 0.2349 | |
| SRP133303 | TTLL7 | 79739 | RNAseq | -1.2437 | 0.0000 | |
| SRP159526 | TTLL7 | 79739 | RNAseq | -0.8077 | 0.0174 | |
| SRP193095 | TTLL7 | 79739 | RNAseq | 0.1818 | 0.4732 | |
| SRP219564 | TTLL7 | 79739 | RNAseq | -0.6558 | 0.4159 | |
| TCGA | TTLL7 | 79739 | RNAseq | -0.9565 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by TTLL7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTLL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTLL7 | 79739 | 0 | 8 | 22 | |
| GSE20123 | TTLL7 | 79739 | 0 | 8 | 22 | |
| GSE43470 | TTLL7 | 79739 | 2 | 2 | 39 | |
| GSE46452 | TTLL7 | 79739 | 0 | 1 | 58 | |
| GSE47630 | TTLL7 | 79739 | 8 | 5 | 27 | |
| GSE54993 | TTLL7 | 79739 | 0 | 0 | 70 | |
| GSE54994 | TTLL7 | 79739 | 6 | 3 | 44 | |
| GSE60625 | TTLL7 | 79739 | 0 | 0 | 11 | |
| GSE74703 | TTLL7 | 79739 | 1 | 2 | 33 | |
| GSE74704 | TTLL7 | 79739 | 0 | 5 | 15 | |
| TCGA | TTLL7 | 79739 | 8 | 23 | 65 |
Total number of gains: 25; Total number of losses: 57; Total Number of normals: 406.
Somatic mutations of TTLL7:
Generating mutation plots.
Highly correlated genes for TTLL7:
Showing top 20/918 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTLL7 | ANKS1B | 0.874515 | 3 | 0 | 3 |
| TTLL7 | RASSF3 | 0.829456 | 3 | 0 | 3 |
| TTLL7 | PRR26 | 0.793228 | 3 | 0 | 3 |
| TTLL7 | CLMP | 0.767285 | 3 | 0 | 3 |
| TTLL7 | SORCS1 | 0.765072 | 4 | 0 | 4 |
| TTLL7 | FBXO30 | 0.75922 | 4 | 0 | 4 |
| TTLL7 | PODN | 0.736036 | 3 | 0 | 3 |
| TTLL7 | FAM13B | 0.732262 | 5 | 0 | 5 |
| TTLL7 | SORBS1 | 0.731968 | 4 | 0 | 3 |
| TTLL7 | CADM2 | 0.730999 | 4 | 0 | 3 |
| TTLL7 | MYADM | 0.728952 | 4 | 0 | 3 |
| TTLL7 | UBXN10 | 0.726839 | 4 | 0 | 3 |
| TTLL7 | SLC35F1 | 0.724661 | 4 | 0 | 3 |
| TTLL7 | GIPC3 | 0.721497 | 3 | 0 | 3 |
| TTLL7 | FLNC | 0.7158 | 7 | 0 | 6 |
| TTLL7 | CORO6 | 0.703807 | 4 | 0 | 3 |
| TTLL7 | XKR4 | 0.700751 | 5 | 0 | 3 |
| TTLL7 | SMTN | 0.700666 | 6 | 0 | 5 |
| TTLL7 | MAP1LC3A | 0.697133 | 3 | 0 | 3 |
| TTLL7 | AP1S2 | 0.694209 | 6 | 0 | 5 |
For details and further investigation, click here
