| Full name: ADAMTS like 1 | Alias Symbol: ADAMTSR1|FLJ35283 | ||
| Type: protein-coding gene | Cytoband: 9p22.2-p22.1 | ||
| Entrez ID: 92949 | HGNC ID: HGNC:14632 | Ensembl Gene: ENSG00000178031 | OMIM ID: 609198 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTSL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTSL1 | 92949 | 229585_at | -1.4749 | 0.1946 | |
| GSE26886 | ADAMTSL1 | 92949 | 229585_at | 0.3077 | 0.0064 | |
| GSE45670 | ADAMTSL1 | 92949 | 229585_at | -1.8561 | 0.0000 | |
| GSE53622 | ADAMTSL1 | 92949 | 167997 | -1.2851 | 0.0000 | |
| GSE53624 | ADAMTSL1 | 92949 | 95395 | -0.8676 | 0.0000 | |
| GSE63941 | ADAMTSL1 | 92949 | 229585_at | -0.5808 | 0.1810 | |
| GSE77861 | ADAMTSL1 | 92949 | 239909_at | -0.0600 | 0.5830 | |
| GSE97050 | ADAMTSL1 | 92949 | A_33_P3302025 | -1.0160 | 0.1298 | |
| SRP007169 | ADAMTSL1 | 92949 | RNAseq | 1.3586 | 0.1245 | |
| SRP064894 | ADAMTSL1 | 92949 | RNAseq | -0.3169 | 0.4663 | |
| SRP133303 | ADAMTSL1 | 92949 | RNAseq | -2.2955 | 0.0000 | |
| SRP159526 | ADAMTSL1 | 92949 | RNAseq | -1.2268 | 0.0668 | |
| SRP219564 | ADAMTSL1 | 92949 | RNAseq | 0.0091 | 0.9937 | |
| TCGA | ADAMTSL1 | 92949 | RNAseq | -1.2991 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ADAMTSL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTSL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTSL1 | 92949 | 2 | 16 | 12 | |
| GSE20123 | ADAMTSL1 | 92949 | 2 | 16 | 12 | |
| GSE43470 | ADAMTSL1 | 92949 | 4 | 11 | 28 | |
| GSE46452 | ADAMTSL1 | 92949 | 2 | 23 | 34 | |
| GSE47630 | ADAMTSL1 | 92949 | 3 | 27 | 10 | |
| GSE54993 | ADAMTSL1 | 92949 | 6 | 2 | 62 | |
| GSE54994 | ADAMTSL1 | 92949 | 9 | 16 | 28 | |
| GSE60625 | ADAMTSL1 | 92949 | 0 | 0 | 11 | |
| GSE74703 | ADAMTSL1 | 92949 | 4 | 8 | 24 | |
| GSE74704 | ADAMTSL1 | 92949 | 0 | 13 | 7 | |
| TCGA | ADAMTSL1 | 92949 | 14 | 51 | 31 |
Total number of gains: 46; Total number of losses: 183; Total Number of normals: 259.
Somatic mutations of ADAMTSL1:
Generating mutation plots.
Highly correlated genes for ADAMTSL1:
Showing top 20/692 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTSL1 | TMOD1 | 0.868262 | 3 | 0 | 3 |
| ADAMTSL1 | PGR | 0.853812 | 5 | 0 | 5 |
| ADAMTSL1 | SGCA | 0.837074 | 5 | 0 | 5 |
| ADAMTSL1 | MYOC | 0.829931 | 5 | 0 | 5 |
| ADAMTSL1 | SORCS1 | 0.825448 | 4 | 0 | 4 |
| ADAMTSL1 | NEGR1 | 0.816767 | 6 | 0 | 6 |
| ADAMTSL1 | ZNF385D | 0.815969 | 5 | 0 | 5 |
| ADAMTSL1 | PCDH9 | 0.81302 | 5 | 0 | 5 |
| ADAMTSL1 | MYOT | 0.807663 | 5 | 0 | 5 |
| ADAMTSL1 | UBXN10 | 0.803763 | 3 | 0 | 3 |
| ADAMTSL1 | ALDH1A2 | 0.80166 | 4 | 0 | 4 |
| ADAMTSL1 | PGM5 | 0.793947 | 5 | 0 | 5 |
| ADAMTSL1 | SH3BGR | 0.793193 | 5 | 0 | 5 |
| ADAMTSL1 | MGARP | 0.790358 | 3 | 0 | 3 |
| ADAMTSL1 | MTURN | 0.789734 | 4 | 0 | 4 |
| ADAMTSL1 | ADAMTSL3 | 0.781444 | 4 | 0 | 4 |
| ADAMTSL1 | DACT3 | 0.780286 | 6 | 0 | 6 |
| ADAMTSL1 | DPT | 0.780235 | 6 | 0 | 6 |
| ADAMTSL1 | TNS1 | 0.779654 | 6 | 0 | 6 |
| ADAMTSL1 | BHMT2 | 0.778809 | 6 | 0 | 6 |
For details and further investigation, click here
