| Full name: DEAH-box helicase 37 | Alias Symbol: KIAA1517|MGC4322|MGC2695|Dhr1 | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 57647 | HGNC ID: HGNC:17210 | Ensembl Gene: ENSG00000150990 | OMIM ID: 617362 |
| Drug and gene relationship at DGIdb | |||
Expression of DHX37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX37 | 57647 | 223365_at | 0.6609 | 0.0132 | |
| GSE26886 | DHX37 | 57647 | 223365_at | 0.9129 | 0.0000 | |
| GSE45670 | DHX37 | 57647 | 223365_at | 0.2763 | 0.0039 | |
| GSE53622 | DHX37 | 57647 | 61940 | 0.3908 | 0.0000 | |
| GSE53624 | DHX37 | 57647 | 61940 | 0.7243 | 0.0000 | |
| GSE63941 | DHX37 | 57647 | 223365_at | -0.2218 | 0.1960 | |
| GSE77861 | DHX37 | 57647 | 223365_at | 0.0475 | 0.7601 | |
| GSE97050 | DHX37 | 57647 | A_23_P13914 | 0.2327 | 0.3001 | |
| SRP007169 | DHX37 | 57647 | RNAseq | 1.3518 | 0.0074 | |
| SRP008496 | DHX37 | 57647 | RNAseq | 0.8981 | 0.0129 | |
| SRP064894 | DHX37 | 57647 | RNAseq | 0.6499 | 0.0001 | |
| SRP133303 | DHX37 | 57647 | RNAseq | 0.3307 | 0.0419 | |
| SRP159526 | DHX37 | 57647 | RNAseq | 0.3855 | 0.1172 | |
| SRP193095 | DHX37 | 57647 | RNAseq | 0.5634 | 0.0000 | |
| SRP219564 | DHX37 | 57647 | RNAseq | 0.2442 | 0.3404 | |
| TCGA | DHX37 | 57647 | RNAseq | 0.1451 | 0.0068 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DHX37 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX37 | 57647 | 5 | 5 | 20 | |
| GSE20123 | DHX37 | 57647 | 5 | 5 | 20 | |
| GSE43470 | DHX37 | 57647 | 2 | 0 | 41 | |
| GSE46452 | DHX37 | 57647 | 9 | 1 | 49 | |
| GSE47630 | DHX37 | 57647 | 9 | 3 | 28 | |
| GSE54993 | DHX37 | 57647 | 0 | 5 | 65 | |
| GSE54994 | DHX37 | 57647 | 4 | 8 | 41 | |
| GSE60625 | DHX37 | 57647 | 0 | 0 | 11 | |
| GSE74703 | DHX37 | 57647 | 2 | 0 | 34 | |
| GSE74704 | DHX37 | 57647 | 3 | 3 | 14 | |
| TCGA | DHX37 | 57647 | 21 | 12 | 63 |
Total number of gains: 60; Total number of losses: 42; Total Number of normals: 386.
Somatic mutations of DHX37:
Generating mutation plots.
Highly correlated genes for DHX37:
Showing top 20/1371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX37 | ROMO1 | 0.853327 | 3 | 0 | 3 |
| DHX37 | U2SURP | 0.819294 | 4 | 0 | 4 |
| DHX37 | MRPS17 | 0.814311 | 3 | 0 | 3 |
| DHX37 | CCT6A | 0.8112 | 3 | 0 | 3 |
| DHX37 | NCAPG | 0.798246 | 4 | 0 | 4 |
| DHX37 | SLC39A3 | 0.795937 | 4 | 0 | 4 |
| DHX37 | CASK | 0.789448 | 3 | 0 | 3 |
| DHX37 | CDC25A | 0.781928 | 5 | 0 | 5 |
| DHX37 | EFTUD2 | 0.781259 | 6 | 0 | 6 |
| DHX37 | TBRG4 | 0.780142 | 3 | 0 | 3 |
| DHX37 | NOC2L | 0.773901 | 4 | 0 | 4 |
| DHX37 | NACC1 | 0.768072 | 4 | 0 | 4 |
| DHX37 | TFDP2 | 0.766991 | 3 | 0 | 3 |
| DHX37 | SLC52A1 | 0.766952 | 3 | 0 | 3 |
| DHX37 | PACS1 | 0.765221 | 3 | 0 | 3 |
| DHX37 | CCDC86 | 0.764796 | 4 | 0 | 4 |
| DHX37 | ORC2 | 0.763361 | 3 | 0 | 3 |
| DHX37 | GORAB | 0.762742 | 3 | 0 | 3 |
| DHX37 | ADRM1 | 0.760175 | 6 | 0 | 6 |
| DHX37 | GLI3 | 0.757283 | 3 | 0 | 3 |
For details and further investigation, click here
