CSRP2

 

Full name: cysteine and glycine rich protein 2 Alias Symbol: SmLIM|CRP2|LMO5
Type: protein-coding gene Cytoband: 12q21.2
Entrez ID: 1466 HGNC ID: HGNC:2470 Ensembl Gene: ENSG00000175183 OMIM ID: 601871
Drug and gene relationship at DGIdb

 

Expression of CSRP2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CSRP2 1466 207030_s_at -0.1350 0.8800
GSE20347 CSRP2 1466 207030_s_at -0.3244 0.1631
GSE23400 CSRP2 1466 207030_s_at -0.2982 0.0562
GSE26886 CSRP2 1466 207030_s_at -0.9941 0.0012
GSE29001 CSRP2 1466 207030_s_at 0.2968 0.6803
GSE38129 CSRP2 1466 207030_s_at -0.4228 0.0124
GSE45670 CSRP2 1466 207030_s_at -0.0156 0.9639
GSE53622 CSRP2 1466 122453 -0.3343 0.0057
GSE53624 CSRP2 1466 122453 -0.2327 0.0217
GSE63941 CSRP2 1466 207030_s_at -2.1155 0.0808
GSE77861 CSRP2 1466 207030_s_at -0.1210 0.7918
GSE97050 CSRP2 1466 A_23_P44724 -0.3790 0.2226
SRP007169 CSRP2 1466 RNAseq 0.3716 0.4102
SRP008496 CSRP2 1466 RNAseq 0.0527 0.8366
SRP064894 CSRP2 1466 RNAseq -0.6383 0.0021
SRP133303 CSRP2 1466 RNAseq -0.1747 0.6238
SRP159526 CSRP2 1466 RNAseq -0.3786 0.4123
SRP193095 CSRP2 1466 RNAseq -0.5634 0.0361
SRP219564 CSRP2 1466 RNAseq -0.9478 0.1277
TCGA CSRP2 1466 RNAseq 0.1391 0.2040

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by CSRP2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CSRP2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CSRP2 1466 3 4 23
GSE20123 CSRP2 1466 3 4 23
GSE43470 CSRP2 1466 3 1 39
GSE46452 CSRP2 1466 8 1 50
GSE47630 CSRP2 1466 10 1 29
GSE54993 CSRP2 1466 0 5 65
GSE54994 CSRP2 1466 6 1 46
GSE60625 CSRP2 1466 0 0 11
GSE74703 CSRP2 1466 3 1 32
GSE74704 CSRP2 1466 2 2 16
TCGA CSRP2 1466 14 15 67

Total number of gains: 52; Total number of losses: 35; Total Number of normals: 401.  


 

Somatic mutations of CSRP2:

 

Generating mutation plots.

 

Highly correlated genes for CSRP2:

 

Showing top 20/158 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CSRP2DPH50.732858303
CSRP2AGGF10.72603303
CSRP2KCTD210.721931303
CSRP2HNRNPA00.7205303
CSRP2KPNA30.698203303
CSRP2WDR370.693257303
CSRP2CHMP50.691283303
CSRP2SNW10.691125303
CSRP2ITFG20.69048303
CSRP2ZNF2560.688377303
CSRP2DEK0.683799303
CSRP2LIPA0.678969303
CSRP2BTN3A20.67731303
CSRP2ST3GAL60.676362303
CSRP2NPHP30.671208303
CSRP2SLC30A50.665728303
CSRP2MBLAC20.662778403
CSRP2ATP9A0.661706303
CSRP2ZNF5730.661671303
CSRP2GNAI10.660963504

For details and further investigation, click here