| Full name: ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | Alias Symbol: ST3GALVI | ||
| Type: protein-coding gene | Cytoband: 3q12.1 | ||
| Entrez ID: 10402 | HGNC ID: HGNC:18080 | Ensembl Gene: ENSG00000064225 | OMIM ID: 607156 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ST3GAL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST3GAL6 | 10402 | 213355_at | -0.3695 | 0.3817 | |
| GSE20347 | ST3GAL6 | 10402 | 213335_s_at | -0.0480 | 0.4974 | |
| GSE23400 | ST3GAL6 | 10402 | 210942_s_at | 0.0005 | 0.9910 | |
| GSE26886 | ST3GAL6 | 10402 | 213355_at | -0.9584 | 0.0030 | |
| GSE29001 | ST3GAL6 | 10402 | 213355_at | -0.3815 | 0.5624 | |
| GSE38129 | ST3GAL6 | 10402 | 213355_at | 0.0281 | 0.9088 | |
| GSE45670 | ST3GAL6 | 10402 | 213355_at | -0.0185 | 0.9643 | |
| GSE53622 | ST3GAL6 | 10402 | 7409 | 0.1299 | 0.3160 | |
| GSE53624 | ST3GAL6 | 10402 | 7409 | -0.0830 | 0.4638 | |
| GSE63941 | ST3GAL6 | 10402 | 210942_s_at | -1.1543 | 0.1839 | |
| GSE77861 | ST3GAL6 | 10402 | 213355_at | -0.1980 | 0.1281 | |
| GSE97050 | ST3GAL6 | 10402 | A_23_P250800 | 0.0295 | 0.9347 | |
| SRP007169 | ST3GAL6 | 10402 | RNAseq | -0.6359 | 0.2599 | |
| SRP008496 | ST3GAL6 | 10402 | RNAseq | -0.3659 | 0.3417 | |
| SRP064894 | ST3GAL6 | 10402 | RNAseq | 0.2808 | 0.1621 | |
| SRP133303 | ST3GAL6 | 10402 | RNAseq | 0.1187 | 0.4762 | |
| SRP193095 | ST3GAL6 | 10402 | RNAseq | 0.0210 | 0.9003 | |
| SRP219564 | ST3GAL6 | 10402 | RNAseq | 0.5709 | 0.0504 | |
| TCGA | ST3GAL6 | 10402 | RNAseq | -0.5328 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ST3GAL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST3GAL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST3GAL6 | 10402 | 20 | 1 | 9 | |
| GSE20123 | ST3GAL6 | 10402 | 19 | 1 | 10 | |
| GSE43470 | ST3GAL6 | 10402 | 18 | 1 | 24 | |
| GSE46452 | ST3GAL6 | 10402 | 12 | 6 | 41 | |
| GSE47630 | ST3GAL6 | 10402 | 16 | 6 | 18 | |
| GSE54993 | ST3GAL6 | 10402 | 2 | 5 | 63 | |
| GSE54994 | ST3GAL6 | 10402 | 27 | 5 | 21 | |
| GSE60625 | ST3GAL6 | 10402 | 0 | 6 | 5 | |
| GSE74703 | ST3GAL6 | 10402 | 14 | 1 | 21 | |
| GSE74704 | ST3GAL6 | 10402 | 14 | 1 | 5 | |
| TCGA | ST3GAL6 | 10402 | 49 | 10 | 37 |
Total number of gains: 191; Total number of losses: 43; Total Number of normals: 254.
Somatic mutations of ST3GAL6:
Generating mutation plots.
Highly correlated genes for ST3GAL6:
Showing top 20/327 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST3GAL6 | TMCC1 | 0.78739 | 3 | 0 | 3 |
| ST3GAL6 | GFPT1 | 0.756495 | 3 | 0 | 3 |
| ST3GAL6 | KCNAB1 | 0.737296 | 3 | 0 | 3 |
| ST3GAL6 | DEF8 | 0.736848 | 4 | 0 | 4 |
| ST3GAL6 | CD99 | 0.734501 | 3 | 0 | 3 |
| ST3GAL6 | TRIM6 | 0.729966 | 3 | 0 | 3 |
| ST3GAL6 | FAM47A | 0.72876 | 3 | 0 | 3 |
| ST3GAL6 | TBC1D20 | 0.717236 | 3 | 0 | 3 |
| ST3GAL6 | MACROD2 | 0.704452 | 4 | 0 | 4 |
| ST3GAL6 | TMEM218 | 0.703476 | 3 | 0 | 3 |
| ST3GAL6 | GPCPD1 | 0.693486 | 3 | 0 | 3 |
| ST3GAL6 | USP38 | 0.692964 | 3 | 0 | 3 |
| ST3GAL6 | UBE2E1 | 0.690462 | 4 | 0 | 4 |
| ST3GAL6 | FAM83D | 0.68265 | 3 | 0 | 3 |
| ST3GAL6 | E2F8 | 0.681763 | 4 | 0 | 4 |
| ST3GAL6 | OSBPL10 | 0.681471 | 3 | 0 | 3 |
| ST3GAL6 | ZMAT1 | 0.68135 | 3 | 0 | 3 |
| ST3GAL6 | SYTL4 | 0.679237 | 4 | 0 | 3 |
| ST3GAL6 | OSCAR | 0.67709 | 3 | 0 | 3 |
| ST3GAL6 | CSRP2 | 0.676362 | 3 | 0 | 3 |
For details and further investigation, click here
