| Full name: integrin alpha FG-GAP repeat containing 2 | Alias Symbol: MDS028 | ||
| Type: protein-coding gene | Cytoband: 12p13.33 | ||
| Entrez ID: 55846 | HGNC ID: HGNC:30879 | Ensembl Gene: ENSG00000111203 | OMIM ID: 617421 |
| Drug and gene relationship at DGIdb | |||
Expression of ITFG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ITFG2 | 55846 | 220590_at | -0.0526 | 0.8684 | |
| GSE20347 | ITFG2 | 55846 | 220590_at | -0.0875 | 0.4718 | |
| GSE23400 | ITFG2 | 55846 | 220590_at | -0.0459 | 0.1284 | |
| GSE26886 | ITFG2 | 55846 | 220590_at | -0.5649 | 0.0096 | |
| GSE29001 | ITFG2 | 55846 | 220590_at | 0.0920 | 0.6053 | |
| GSE38129 | ITFG2 | 55846 | 220590_at | -0.2152 | 0.1564 | |
| GSE45670 | ITFG2 | 55846 | 220590_at | 0.3104 | 0.0159 | |
| GSE53622 | ITFG2 | 55846 | 116008 | 0.1374 | 0.1131 | |
| GSE53624 | ITFG2 | 55846 | 116008 | 0.1815 | 0.0360 | |
| GSE63941 | ITFG2 | 55846 | 220590_at | 0.4132 | 0.1269 | |
| GSE77861 | ITFG2 | 55846 | 220590_at | -0.0932 | 0.5992 | |
| GSE97050 | ITFG2 | 55846 | A_23_P204417 | -0.1135 | 0.5506 | |
| SRP007169 | ITFG2 | 55846 | RNAseq | 0.3199 | 0.4952 | |
| SRP008496 | ITFG2 | 55846 | RNAseq | 0.4108 | 0.2575 | |
| SRP064894 | ITFG2 | 55846 | RNAseq | -0.1636 | 0.1644 | |
| SRP133303 | ITFG2 | 55846 | RNAseq | -0.0614 | 0.7425 | |
| SRP159526 | ITFG2 | 55846 | RNAseq | -0.1024 | 0.7257 | |
| SRP193095 | ITFG2 | 55846 | RNAseq | -0.1683 | 0.1626 | |
| SRP219564 | ITFG2 | 55846 | RNAseq | -0.1590 | 0.4929 | |
| TCGA | ITFG2 | 55846 | RNAseq | -0.1562 | 0.0172 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ITFG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ITFG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ITFG2 | 55846 | 6 | 4 | 20 | |
| GSE20123 | ITFG2 | 55846 | 6 | 4 | 20 | |
| GSE43470 | ITFG2 | 55846 | 11 | 4 | 28 | |
| GSE46452 | ITFG2 | 55846 | 10 | 1 | 48 | |
| GSE47630 | ITFG2 | 55846 | 12 | 2 | 26 | |
| GSE54993 | ITFG2 | 55846 | 1 | 10 | 59 | |
| GSE54994 | ITFG2 | 55846 | 9 | 2 | 42 | |
| GSE60625 | ITFG2 | 55846 | 0 | 1 | 10 | |
| GSE74703 | ITFG2 | 55846 | 11 | 2 | 23 | |
| GSE74704 | ITFG2 | 55846 | 4 | 2 | 14 | |
| TCGA | ITFG2 | 55846 | 40 | 6 | 50 |
Total number of gains: 110; Total number of losses: 38; Total Number of normals: 340.
Somatic mutations of ITFG2:
Generating mutation plots.
Highly correlated genes for ITFG2:
Showing top 20/111 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ITFG2 | TBRG1 | 0.77159 | 3 | 0 | 3 |
| ITFG2 | RASA2 | 0.717403 | 3 | 0 | 3 |
| ITFG2 | TAGAP | 0.717071 | 3 | 0 | 3 |
| ITFG2 | MRPL46 | 0.715552 | 3 | 0 | 3 |
| ITFG2 | OFD1 | 0.692908 | 4 | 0 | 4 |
| ITFG2 | CSRP2 | 0.69048 | 3 | 0 | 3 |
| ITFG2 | SYNE2 | 0.67719 | 3 | 0 | 3 |
| ITFG2 | PANK1 | 0.673335 | 3 | 0 | 3 |
| ITFG2 | CLN8 | 0.673177 | 3 | 0 | 3 |
| ITFG2 | PRPSAP1 | 0.671535 | 3 | 0 | 3 |
| ITFG2 | ANKRD36B | 0.663262 | 4 | 0 | 3 |
| ITFG2 | SERPINB9 | 0.662402 | 3 | 0 | 3 |
| ITFG2 | HADH | 0.657723 | 3 | 0 | 3 |
| ITFG2 | SNRNP200 | 0.655563 | 4 | 0 | 3 |
| ITFG2 | NOTCH2 | 0.651676 | 4 | 0 | 3 |
| ITFG2 | ZFP3 | 0.649547 | 4 | 0 | 4 |
| ITFG2 | CCZ1B | 0.646907 | 4 | 0 | 4 |
| ITFG2 | PKN2 | 0.646877 | 4 | 0 | 3 |
| ITFG2 | ZNF136 | 0.642198 | 4 | 0 | 4 |
| ITFG2 | POU2F2 | 0.641929 | 3 | 0 | 3 |
For details and further investigation, click here
