| Full name: CUE domain containing 2 | Alias Symbol: MGC2491 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 79004 | HGNC ID: HGNC:28352 | Ensembl Gene: ENSG00000107874 | OMIM ID: 614142 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CUEDC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CUEDC2 | 79004 | 218097_s_at | 0.1460 | 0.7747 | |
| GSE20347 | CUEDC2 | 79004 | 218097_s_at | 0.1394 | 0.3944 | |
| GSE23400 | CUEDC2 | 79004 | 218097_s_at | 0.1390 | 0.0159 | |
| GSE26886 | CUEDC2 | 79004 | 218097_s_at | 0.9726 | 0.0000 | |
| GSE29001 | CUEDC2 | 79004 | 218097_s_at | -0.0260 | 0.9552 | |
| GSE38129 | CUEDC2 | 79004 | 218097_s_at | -0.0148 | 0.9486 | |
| GSE45670 | CUEDC2 | 79004 | 218097_s_at | -0.2242 | 0.0931 | |
| GSE53622 | CUEDC2 | 79004 | 42563 | 0.1129 | 0.1472 | |
| GSE53624 | CUEDC2 | 79004 | 42563 | 0.2796 | 0.0000 | |
| GSE63941 | CUEDC2 | 79004 | 218097_s_at | -0.1857 | 0.6713 | |
| GSE77861 | CUEDC2 | 79004 | 218097_s_at | 0.1538 | 0.5819 | |
| GSE97050 | CUEDC2 | 79004 | A_23_P127088 | 0.0382 | 0.9006 | |
| SRP007169 | CUEDC2 | 79004 | RNAseq | -0.0759 | 0.8254 | |
| SRP008496 | CUEDC2 | 79004 | RNAseq | 0.1606 | 0.5312 | |
| SRP064894 | CUEDC2 | 79004 | RNAseq | 0.3454 | 0.2929 | |
| SRP133303 | CUEDC2 | 79004 | RNAseq | 0.0342 | 0.8002 | |
| SRP159526 | CUEDC2 | 79004 | RNAseq | 0.2849 | 0.1995 | |
| SRP193095 | CUEDC2 | 79004 | RNAseq | 0.2905 | 0.0054 | |
| SRP219564 | CUEDC2 | 79004 | RNAseq | 0.0714 | 0.8927 | |
| TCGA | CUEDC2 | 79004 | RNAseq | -0.0681 | 0.2482 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CUEDC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CUEDC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CUEDC2 | 79004 | 2 | 9 | 19 | |
| GSE20123 | CUEDC2 | 79004 | 2 | 8 | 20 | |
| GSE43470 | CUEDC2 | 79004 | 0 | 8 | 35 | |
| GSE46452 | CUEDC2 | 79004 | 0 | 11 | 48 | |
| GSE47630 | CUEDC2 | 79004 | 2 | 14 | 24 | |
| GSE54993 | CUEDC2 | 79004 | 8 | 0 | 62 | |
| GSE54994 | CUEDC2 | 79004 | 1 | 11 | 41 | |
| GSE60625 | CUEDC2 | 79004 | 0 | 0 | 11 | |
| GSE74703 | CUEDC2 | 79004 | 0 | 5 | 31 | |
| GSE74704 | CUEDC2 | 79004 | 1 | 4 | 15 | |
| TCGA | CUEDC2 | 79004 | 6 | 28 | 62 |
Total number of gains: 22; Total number of losses: 98; Total Number of normals: 368.
Somatic mutations of CUEDC2:
Generating mutation plots.
Highly correlated genes for CUEDC2:
Showing top 20/927 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CUEDC2 | PATZ1 | 0.728739 | 5 | 0 | 4 |
| CUEDC2 | SOX13 | 0.725468 | 3 | 0 | 3 |
| CUEDC2 | ZHX2 | 0.720986 | 3 | 0 | 3 |
| CUEDC2 | C15orf61 | 0.715021 | 4 | 0 | 4 |
| CUEDC2 | RAB34 | 0.712403 | 3 | 0 | 3 |
| CUEDC2 | ZSCAN21 | 0.709274 | 4 | 0 | 3 |
| CUEDC2 | CENPV | 0.707924 | 6 | 0 | 6 |
| CUEDC2 | CRLS1 | 0.7004 | 3 | 0 | 3 |
| CUEDC2 | SLC7A6 | 0.700193 | 3 | 0 | 3 |
| CUEDC2 | MRPL17 | 0.700175 | 3 | 0 | 3 |
| CUEDC2 | ZNF32 | 0.697263 | 10 | 0 | 9 |
| CUEDC2 | LSM10 | 0.693434 | 4 | 0 | 4 |
| CUEDC2 | ZNF703 | 0.692517 | 4 | 0 | 4 |
| CUEDC2 | CAMKK2 | 0.691143 | 3 | 0 | 3 |
| CUEDC2 | CDKN1C | 0.687542 | 4 | 0 | 4 |
| CUEDC2 | DENND1A | 0.686464 | 5 | 0 | 5 |
| CUEDC2 | LRRK1 | 0.685616 | 3 | 0 | 3 |
| CUEDC2 | ZNF418 | 0.685046 | 3 | 0 | 3 |
| CUEDC2 | PRR16 | 0.680545 | 3 | 0 | 3 |
| CUEDC2 | PELI3 | 0.676107 | 4 | 0 | 4 |
For details and further investigation, click here
